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DOI :
10.3791/53510-v
January 20th, 2016
Chapters
0:05
Title
0:48
Crosslinking in Live Cells
3:19
Isolation of Chromatin
5:14
Capture of Ligand-DNA Crosslinks and Isolation of Affinity-purified DNA
7:52
Results: COSMIC Indentifies Genome-wide Binding Events of Polyamides
9:21
Conclusion
게놈 대상 분자의 직접적인 목표를 확인하는 것은 중요한 과제로 남아. DNA 결합 분자 게놈 참여 방법을 이해하기 위해, 우리는 염색질을 분리하는 작은 분자의 가교에 의존하는 방법 (COSMIC)을 개발.
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