Name: somatosensory event-related potentials from orofacial skin stretch stimulation
Uploaded: 2015-12-18T14:00:00
Description: Watch this Scientific Journal Video about Somatosensory Event-related Potentials from Orofacial Skin Stretch Stimulation at JoVE.com

この作品は、難聴やその他のコミュニケーション障害補助金R21DC013915とR01DC012502、自然科学とカナダの工学研究評議会及び欧州共同体のセブンス枠組み計画（FP7 / 2007から2013グラント契約がない下での欧州研究評議会の国立研究所によってサポートされていました。339152 ）。

現在の実験プロトコルは、イェール大学人間調査委員会によると、倫理的な行動の指針に従っています。 1. Electroenchephalopgaphy（EEG）の準備<ol><li>適切な脳波キャップを決定するために、ヘッドサイズを測定します。 </li><li>測定テープでナジオンとイニオン間の中間点を見つけることによって、頂点の位置を特定します。 </li><li> Czにとして予め定められた頂点を使用して、頭の上に脳?...

<ol>
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ここで報告された研究では、顔の皮膚の変形によって生成され、正確に制御体性感覚刺激は、皮質のERPを誘発する証拠を提供します。皮膚求心性神経は、人間の四肢運動5,6と音声動き7,8,21における運動感覚情報3,4の豊富な供給源として知られています。話す時の実際の移動方向を反映した方法で、顔の皮膚をストレッチすると、対応する動きに似た運動感覚を誘発し?...

スピーチの生産は、聴覚と体性感覚情報の両方に依存しています。聴覚と体性感覚フィードバックは、幼児によって生成最古の発声からの組み合わせで発生し、両方のは、音声運動学習に関与しています。最近の結果は、体性感覚プロセスは知覚だけでなく、生産に寄与することを示唆しています。例えば、音声の識別は、参加者が聴覚刺激1に耳を傾けるように、ロボット装置は、顔の皮膚を伸ばしたときに変更されている鳴ります。聴覚音声刺激と一致頬に空気パフは、参加者の知覚判断を変える2。 これらの体性感覚の効果は、皮膚の変形に応じて皮膚の機械受容器の活性化を含みます。皮膚は、移動中に、様々な方法で変形され、そして皮膚の機械受容は力覚3,4に寄与することが知られています。皮膚の機械受容の運動感覚役割は悪魔であります運動に関連した皮膚の株が適切に皮膚ストレッチ6のパターンに応じて屈曲または延長の動きとして認識されている最近の知見5-7によりstrated。付随顔の皮膚の伸縮性のスピーチで、特定の発話の繰り返しである音声モーター訓練のコースで、調音パターンが適応的に変更する7。これらの研究は、動作中に、皮膚の伸張を調節する感覚系の運動感覚機能の皮膚求心性の寄与を評価するための方法を提供することを示しています。 口腔顔面皮膚の機械受容の運動感覚機能は、感覚神経9,10から再コーディング精神生理学的方法7,8および微小電極を用いて、主に研究されてきました。ここでは、現在のプロトコルは、顔の皮膚の変形や事象関連電位（ERP）記録に関連する口腔顔面体性感覚刺激の組み合わせに焦点を当てています。目ある手順では、コンピュータ制御のロボット装置を使用して、顔の皮膚の変形方向とタイミングを正確に実験的に制御することができます。これは、私たちは選択的かつ正確に音声運動学習と直接音声生成と知覚の両方の間の方向の広い範囲で顔の皮膚を変形させることにより音声生成と知覚の体性感覚の寄与についての特定の仮説をテストすることができます。 ERP記録を非侵襲的に口腔顔面行動上の体性感覚刺激の影響の時間的パターンおよびタイミングを評価するために使用されます。現在のプロトコルは、その後、運動感覚機能の神経相関を評価し、音声処理、音声生成と音声知覚の両方に体性感覚系の寄与を評価することができます。 ERP記録にスキンストレッチ刺激のアプリケーションの有用性を示すために、以下のプロトコルは、音声Pにおける体性感覚と聴覚入力の相互作用に焦点を当ててerception。結果は演説の中で体性感覚、聴覚の相互作用を評価するための潜在的な方法を強調表示します。

<table border="0" cellpadding="0" cellspacing="0" width="673">
	<tbody>
		<tr height="21">
			<td height="21" style="height:21px;width:216px;">EEG recording system</td>
			<td style="width:163px;">Biosemi</td>
			<td style="width:147px;">ActiveTwo</td>
			<td style="width:147px;"></td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:216px;">Robotic decice for skin stretch</td>
			<td style="width:163px;">Geomagic</td>
			<td style="width:147px;">Phantom Premium 1.0</td>
			<td></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:216px;">EEG-compatible earphones</td>
			<td style="width:163px;">Etymotic research</td>
			<td style="width:147px;">ER3A</td>
			<td></td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:216px;">Software for visual and auditory stimulation</td>
			<td style="width:163px;">Neurobehavioral Systems</td>
			<td style="width:147px;">Presentation</td>
			<td></td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:216px;">Electrode gel</td>
			<td style="width:163px;">Parker Laboratories, INC</td>
			<td style="width:147px;">Signa gel</td>
			<td></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:216px;">Double sided tape</td>
			<td style="width:163px;">3M</td>
			<td style="width:147px;">1522</td>
			<td></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:216px;">Disposable syringe</td>
			<td style="width:163px;">Monoject</td>
			<td style="width:147px;">412 Curved Tip</td>
			<td></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:216px;">Analog input device</td>
			<td style="width:163px;">National Instuments&#160;</td>
			<td style="width:147px;">PCI-6036E</td>
			<td></td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:216px;">Degital output device</td>
			<td style="width:163px;">Measurement computing</td>
			<td style="width:147px;">USB-1208FS</td>
			<td></td>
		</tr>
	</tbody>
</table>

somatosensory event-related potentials from orofacial skin stretch stimulation

Cortical processing associated with orofacial somatosensory function in speech has received limited experimental attention due to the difficulty of providing precise and controlled stimulation. This article introduces a technique for recording somatosensory event-related potentials (ERP) that uses a novel mechanical stimulation method involving skin deformation using a robotic device. Controlled deformation of the facial skin is used to modulate kinesthetic inputs through excitation of cutaneous mechanoreceptors. By combining somatosensory stimulation with electroencephalographic recording, somatosensory evoked responses can be successfully measured at the level of the cortex. Somatosensory stimulation can be combined with the stimulation of other sensory modalities to assess multisensory interactions. For speech, orofacial stimulation is combined with speech sound stimulation to assess the contribution of multi-sensory processing including the effects of timing differences. The ability to precisely control orofacial somatosensory stimulation during speech perception and speech production with ERP recording is an important tool that provides new insight into the neural organization and neural representations for speech.

このセクションでは、顔の皮膚の変形による体性感覚刺激に応答した代表的な事象関連電位を示しています。実験は、図1に示されている。正弦波刺激が（参考として、 図3Aを参照）経口角度に顔の皮膚の横に適用しました。百ストレッチ試験は合計でテスト12の参加者と参加者ごとに記録しました。水平方向および垂直方向の電気眼球運動記...

Watch this Scientific Journal Video about Somatosensory Event-related Potentials from Orofacial Skin Stretch Stimulation at JoVE.com

Somatosensory Event-related Potentials from Orofacial Skin Stretch Stimulation

This paper introduces a method for obtaining somatosensory event-related potentials following orofacial skin stretch stimulation. The current method can be used to evaluate the contribution of somatosensory afferents to both speech production and speech perception.

口腔顔面皮膚ストレッチ刺激から体性感覚事象関連電位

Cortical processing associated with orofacial somatosensory function in speech has received limited experimental attention due to the difficulty of ...

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Electrode Positioning and Montage in Transcranial Direct Current Stimulation

経頭蓋直流電流刺激で電極の位置とモンタージュ

Transcranial direct current stimulation (tDCS) is a technique that has been intensively investigated in the past decade as this method offers a ...

Applications of EEG Neuroimaging Data: Event-related Potentials, Spectral Power, and Multiscale Entropy

EEGニューロイメージングデータの応用：事象関連電位、スペクトルパワー、およびマルチスケールエントロピー

When considering human neuroimaging data, an appreciation of signal variability represents a fundamental innovation in the way we think about brain ...

Optogenetic Activation of Zebrafish Somatosensory Neurons using ChEF-tdTomato

CHEF-tdTomatoを使用してゼブラフィッシュ体性感覚ニューロンのOptogeneticアクティベーション

Larval  zebrafish are emerging as a model for describing the development and function  of simple neural circuits. Due to their  external fertilization, ...

Extracting Visual Evoked Potentials from EEG Data Recorded During fMRI-guided Transcranial Magnetic Stimulation

fMRIのガイド下経頭蓋磁気刺激中に記録された脳波データからの視覚誘発電位を抽出する

Transcranial Magnetic Stimulation (TMS) is an effective method for establishing a causal link between a cortical area and cognitive/neurophysiological ...

Recording Single Neurons' Action Potentials from Freely Moving Pigeons Across Three Stages of Learning

自由に学習の三つの段階を越えハトを移動する単一ニューロン」の活動電位を記録する

While the subject of learning has attracted immense interest from both behavioral and neural scientists, only relatively few investigators have observed ...

Analysis of Developing Tooth Germ Innervation Using Microfluidic Co-culture Devices

マイクロ流体共培養装置の使用歯胚神経支配の開発の分析

Innervation plays a key role in the development, homeostasis and regeneration of organs and tissues. However, the mechanisms underlying these phenomena ...

How to Find Effects of Stimulus Processing on Event Related Brain Potentials of Close Others when Hyperscanning Partners

検索効果の刺激の処理にイベント関連脳電位の近くに他の方法と Hyperscanning パートナー

The partners of each pair must be able to pass the McGill Friendship Questionnaire without communicating. Each partner is then seated in front of a screen ...

Simultaneous Recordings of Cortical Local Field Potentials, Electrocardiogram, Electromyogram, and Breathing Rhythm from a Freely Moving Rat

皮質局所電界電位、心電図、筋電図、呼吸リズム自由行動ラットからの同時録音

Monitoring the physiological dynamics of the brain and peripheral tissues is necessary for addressing a number of questions about how the brain controls ...