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DOI :
10.3791/53746-v
•
9:26 min
May 16th, 2016
Chapters
0:05
Title
1:07
Intra-articular Injection of Monoiodoacetate (MIA) in the Knee
3:57
Measurement of Mechanical Hypersensitivity (Allodynia)
6:00
Measurement of Weight Bearing Deficit
7:29
Results: Behavioral Changes after MIA Injection
8:22
Conclusion
骨关节炎(OA)或退行性关节病,是与该保持仅部分地由可用镇痛药控制疼痛有关的衰弱状态。动物模型正在开发以改善我们的OA相关的疼痛机制的理解。在这里,我们描述了用于办公自动化疼痛鼠标monoiodoacetate模型的方法。
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