Name: a high performance impedance-based platform for evaporation rate detection
Uploaded: 2016-10-17T15:00:00
Description: Watch this Scientific Journal Video about A High Performance Impedance-based Platform for Evaporation Rate Detection at JoVE.com

这项工作得到了科技部，台湾教育部科技部105-2627-B-005-002主办，在授予数量MOST 104-2221-E-241-001-MY3和。

1.实验芯片模块<ol><li> 制造的氧化铟锡（ITO）通过光刻和化学湿法蚀刻工艺电极片 <ol><li>商业获取ITO基板（370毫米×480毫米×0.5毫米（长x宽x高））与2,600 ITO层（见材料清单）。切片ITO基板以90mm的×90毫米×0.5毫米的玻璃切割器用于在4英寸对准ITO电极图案化工艺的尺寸。 </li><li>使用超声波清洗机清洗ITO玻璃用丙酮，然后用去离子水，每次15分钟。擦干ITO玻璃清洁干燥空气。 </li><li>分配...

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S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+real-time+impedance-sensing+chip+for+the+detection+of+emulsion+phase+separation.">A real-time impedance-sensing chip for the detection of emulsion phase separation.</a> Electrophoresis. 34 (12), 1743-1748 (2013).</li><li>Lin, Y. S., Chen, C. Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+novel+evaporation+detection+system+using+an+impedance+sensing+chip.">A novel evaporation detection system using an impedance sensing chip.</a> Analyst. 139 (22), 5781-5784 (2014).</li><li>Tseng, S. 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蒸发测量在这个基于阻抗的检测关键步骤是测试的解决方案的制备。去离子水不能由于其巨大的阻抗被使用。相反，使用含有导电离子的自来水制备用于实验透明质酸溶液。但是，自来水的电性能不是使用恒定的。因此，归一化，如相对蒸发速率，以水在这项研究中，获得通过作为蒸发的替代指标。该技术的限制是，测试的解决方案必须有电化学表征导电离子。 <p class="jov...

蒸发是一种液体汽化并沿水集体体的气 - 液界面发生。表面附近的水分子，由于水分子的碰撞成为能够从液体中逸出。蒸发速度蒸发的过程中，一个重要的关键因素。一般地，平衡或体积管1-3被广泛使用的，以检测溶液的蒸发。然而，它需要很长的时间来测量的蒸发速率由于平衡或体积管的精度的限制。出于这个原因，一个响应和高灵敏度的仪器必须开发探入蒸发过程的细节。 电化学阻抗谱（EIS）是一个快速响应，在原位阻抗检测电化学系统表征4方面敏感和有效的实验手段。因此，交流阻抗可以以各种呸施加LDS， 如最近对细胞行为5项研究，生物分析检测6-7，电解8，导电聚合物9和电化学提取10。尽管EIS系统已成功应用于多种学科的应用，存在其应用蒸发研究的一个非常小的数字出版物。 透明质酸，高分子量的多糖具有较强的水结合的潜力，是用于化妆品应用公知的保湿剂。一个透明质酸分子可绑定多达500个水分子11和达到1000倍原来体积12。透明质酸的极少量可具有保湿功能13-14。由于高的保湿性，透明质酸已经成为化妆品的保湿剂的产品与世界各地的15个高的商业价值的重要组成部分。 ŧ他的研究提出了基于阻抗新颖装置具有高速检测，小体积的样品的要求，和多个样品测量16-19的方法。它是为重点的解决方案，以此来验证比传统的称重方式创新的检测机制的优越性之间的相对蒸发速率比较。

<table border="0" cellpadding="0" cellspacing="0" width="848">
	<tbody>
		<tr height="28">
			<td height="28" style="height:28px;width:143px;">95 % ethanol</td>
			<td style="width:292px;">Echo Chemical Co., Ltd., Miaoli, Taiwan</td>
			<td style="width:155px;">484000001103C-00EC</td>
			<td style="width:259px;"></td>
		</tr>
		<tr height="45">
			<td height="45" style="height:45px;width:143px;">Acetone</td>
			<td style="width:292px;">Avantor Performance Materials Inc., Center Valley, PA, USA</td>
			<td style="width:155px;">JTB-9005-68</td>
			<td></td>
		</tr>
		<tr height="30">
			<td height="30" style="height:30px;width:143px;">Development solution</td>
			<td style="width:292px;">Kemitek Industrial Crop., Hsinchu, Taiwan</td>
			<td style="width:155px;">12F01031</td>
			<td style="width:259px;">KTD-1</td>
		</tr>
		<tr height="30">
			<td height="30" style="height:30px;width:143px;">Etching solution</td>
			<td style="width:292px;">eSolv Technology Co., Taipei, Taiwan</td>
			<td style="width:155px;"></td>
			<td style="width:259px;">EG-462</td>
		</tr>
		<tr height="45">
			<td height="45" style="height:45px;width:143px;">Hyaluronic acid</td>
			<td style="width:292px;">Shandong Freda Biopharm Co., Ltd., Jinan, China</td>
			<td style="width:155px;">1010212</td>
			<td>Molecular weight 980k, Cosmetic Grade</td>
		</tr>
		<tr height="45">
			<td height="45" style="height:45px;width:143px;">Photoresist solution</td>
			<td style="width:292px;">AZ Electronic Materials Taiwan Co., Ltd., Hsinchu, Taiwan</td>
			<td style="width:155px;">65101M19</td>
			<td style="width:259px;">AZ6112</td>
		</tr>
		<tr height="47">
			<td height="47" style="height:47px;width:143px;">8-well silicone array</td>
			<td style="width:292px;">Greiner bio-one Inc., Frickenhausen, Baden-W&#252;rttemberg, Germany</td>
			<td style="width:155px;">FlexiPERM</td>
			<td></td>
		</tr>
		<tr height="45">
			<td height="45" style="height:45px;width:143px;">ITO glass</td>
			<td style="width:292px;">GemTech Optoelectronics Co., Taoyuan, Taiwan</td>
			<td style="width:155px;"></td>
			<td></td>
		</tr>
		<tr height="43">
			<td height="43" style="height:43px;width:143px;">Vial&#160;</td>
			<td style="width:292px;">Sigma-Aldrich Co. LLC., St. Louis, MO, USA</td>
			<td style="width:155px;">854190</td>
			<td></td>
		</tr>
		<tr height="28">
			<td height="28" style="height:28px;width:143px;">Film photomask</td>
			<td style="width:292px;">Taiwan Mesh Co., Ltd, Taoyuan, Taiwan</td>
			<td style="width:155px;"></td>
			<td></td>
		</tr>
		<tr height="46">
			<td height="46" style="height:46px;width:143px;">Lock-in amplifier</td>
			<td style="width:292px;">Stanford Research Systems, Inc., Palo Alto, CA, USA</td>
			<td style="width:155px;">SR830</td>
			<td></td>
		</tr>
		<tr height="66">
			<td height="66" style="height:66px;width:143px;">Switch relay</td>
			<td style="width:292px;">Instrument Technology Research Center, National Applied Research Laboratories, Hsinchu, Taiwan</td>
			<td style="width:155px;"></td>
			<td></td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:143px;">Electronic balance machine</td>
			<td style="width:292px;">Precisa Co., Dietikon, Switzerland</td>
			<td>XS225A</td>
			<td></td>
		</tr>
	</tbody>
</table>

a high performance impedance-based platform for evaporation rate detection

本文描述了用于在检测到的蒸发速率的新颖的基于阻抗的平台的方法。该模型复合透明质酸这里用于演示的目的。以具有各种浓度的溶液的湿润剂的模型化合物的多个蒸发试验为比较目的进行的。常规的减肥方法被称为蒸发率检测的最简单的，但费时，测量技术。然而，一个明显的缺点是，大量的样品需要和多个样本测试不能在同一时间进行。在文献首次电阻抗传感芯片被成功地应用到在时间共享，连续和自动地实时蒸发调查。而且，试验样品的少0.5毫升需要在此基于阻抗的装置，和一个大的阻抗变化显示各稀soluti之间附件。所提出的高灵敏度和快速响应阻抗传感系统发现超越蒸发率检测方面的传统的减肥方法。

在蒸发过程中，在测试溶液中的导电离子成为浓的减少溶液体积，以及该溶液的阻抗降低。测定重量损失，并在每个测试溶液的蒸发进展阻抗降低的速率。为了比较的目的，在体重损失和阻抗降低的速率的数据标准化为水，然后在图5中绘制在一起。如在图5中所示，重量损失表明了相同的倾向的阻抗，并表明，该相对蒸发速率到水蒸发与透明质酸浓度降低。然而，大量的?...

Watch this Scientific Journal Video about A High Performance Impedance-based Platform for Evaporation Rate Detection at JoVE.com

A High Performance Impedance-based Platform for Evaporation Rate Detection

本文提出了蒸发率检测解决方案的基于阻抗的设备。它提供了明显的优势比传统的减肥方法：快速响应，高灵敏度的检测，一个小样本的要求，多样品测量，并便于拆卸清洗和再利用的目的。

蒸发速率检测一种基于阻抗高性能平台

This paper describes the method of a novel impedance-based platform for the detection of the evaporation rate. The model compound hyaluronic acid was ...

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