Name: palladium n-heterocyclic carbene complexes: synthesis from benzimidazolium salts and catalytic activity in carbon-carbon bond-forming reactions
Uploaded: 2017-07-30T14:00:00
Description: Watch this Scientific Journal Video about Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions at JoVE.com

Nous reconnaissons le soutien financier de la Faculté de pharmacie (Université de Sydney), du Fonds de recherche de l&#39;Université Erciyes et de TUBITAK (1059B141400496). Nous remercions Tim Harland (The University of Sydney) d&#39;avoir édité la vidéo.

Attention: De nombreux solvants volatils sont utilisés dans le cadre des protocoles détaillés ci-dessous, afin d&#39;effectuer toutes les expériences dans une hotte de travail. Portez un équipement de protection individuelle approprié tout au long de la procédure et consultez la fiche signalétique de chaque réactif avant utilisation; Dans le présent document, de brèves informations ont été fournies sur les réactifs et les étapes dangereux. 1. Synthèse et purifi...

<ol>
	<li>Akkoc, S., Gok, Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Synthesis+and+characterization+of+1-phenyl-3-alkylbenzimidazol-2-ylidene+salts+and+their+catalytic+activities+in+the+Heck+and+Suzuki+cross-coupling+reactions.">Synthesis and characterization of 1-phenyl-3-alkylbenzimidazol-2-ylidene salts and their catalytic activities in the Heck and Suzuki cross-coupling reactions.</a> J. Coord. Chem. 66 (8), 1396-1404 (2013).</li><li>Aktas, A., Akkoc, S., Gok, Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Palladium+catalyzed+Mizoroki-Heck+and+Suzuki-Miyaura+reactions+using+naphthalenomethyl-substituted+imidazolidin-2-ylidene+ligands+in+aqueous+media.">Palladium catalyzed Mizoroki-Heck and Suzuki-Miyaura reactions using naphthalenomethyl-substituted imidazolidin-2-ylidene ligands in aqueous media.</a> J. Coord. Chem. 66 (16), 2901-2909 (2013).</li><li>Cetinkaya, B., Alici, B., Ozdemir, I., Bruneau, C., Dixneuf, P. H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=2-imidazoline+and+1,4,5,6-tetrahydropyrimidine-ruthenium(II)+complexes+and+catalytic+synthesis+of+furan.">2-imidazoline and 1,4,5,6-tetrahydropyrimidine-ruthenium(II) complexes and catalytic synthesis of furan.</a> J. Organomet. Chem. 575 (2), 187-192 (1999).</li><li>Chouthaiwale, P. V., Rawat, V., Sudalai, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Pd-catalyzed+selective+hydrosilylation+of+aryl+ketones+and+aldehydes.">Pd-catalyzed selective hydrosilylation of aryl ketones and aldehydes.</a> Tetrahedron Lett. 53 (2), 148-150 (2012).</li><li>Herrmann, W. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=N-heterocyclic+carbenes:+A+new+concept+in+organometallic+catalysis.">N-heterocyclic carbenes: A new concept in organometallic catalysis.</a> Angew. Chem. Int. Ed. 41 (8), 1290-1309 (2002).</li><li>Jensen, T. R., Schaller, C. P., Hillmyer, M. A., Tolman, W. 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D., Plenio, H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+hexahydro-s-indacene+based+NHC+ligand+for+olefin+metathesis+catalysts.">A hexahydro-s-indacene based NHC ligand for olefin metathesis catalysts.</a> J. Organomet. Chem. 710, 68-74 (2012).</li><li>Yigit, M., Yigit, B., Gok, Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Synthesis+of+novel+palladium(II)+N-heterocyclic+carbene+complexes+and+their+catalytic+activities+in+the+direct+C5+arylation+reactions.">Synthesis of novel palladium(II) N-heterocyclic carbene complexes and their catalytic activities in the direct C5 arylation reactions.</a> Inorg. Chim. Acta. 453, 23-28 (2016).</li><li>Yasar, S., Sahin, C., Arslan, M., Ozdemir, I. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Synthesis,+characterization+and+the+Suzuki-Miyaura+coupling+reactions+of+N-heterocyclic+carbene-Pd(II)-pyridine+(PEPPSI)+complexes.">Synthesis, characterization and the Suzuki-Miyaura coupling reactions of N-heterocyclic carbene-Pd(II)-pyridine (PEPPSI) complexes.</a> J. Organomet. Chem. 776, 107-112 (2015).</li><li>Ozdemir, I., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=N-Heterocyclic+carbenes:+Useful+ligands+for+the+palladium-catalysed+direct+C5+arylation+of+heteroaromatics+with+aryl+bromides+or+electron-deficient+aryl+chlorides.">N-Heterocyclic carbenes: Useful ligands for the palladium-catalysed direct C5 arylation of heteroaromatics with aryl bromides or electron-deficient aryl chlorides.</a> Eur. J. Inorg. Chem. 12 (12), 1798-1805 (2010).</li><li>Clavier, H., Nolan, S. P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=N-heterocyclic+carbene+and+phosphine+ruthenium+indenylidene+precatalysts:+A+comparative+study+in+Olefin+metathesis.">N-heterocyclic carbene and phosphine ruthenium indenylidene precatalysts: A comparative study in Olefin metathesis.</a> Chem. Eur. J. 13 (28), 8029-8036 (2007).</li><li>Johnson, J. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Catalyzed+reactions+of+acyl+anion+equivalents.">Catalyzed reactions of acyl anion equivalents.</a> Angew. Chem. Int. Ed. 43 (11), 1326-1328 (2004).</li><li>Marion, N., Diez-Gonzalez, S., Nolan, S. P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=N-heterocyclic+carbenes+as+organocatalysts.">N-heterocyclic carbenes as organocatalysts.</a> Angew. Chem. Int. Ed. 46 (17), 2988-3000 (2007).</li><li>Perry, M. C., Burgess, K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Chiral+N-heterocyclic+carbene-transition+metal+complexes+in+asymmetric+catalysis.">Chiral N-heterocyclic carbene-transition metal complexes in asymmetric catalysis.</a> Tetrahedron: Asymmetry. 14 (8), 951-961 (2003).</li><li>Zeitler, K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Extending+mechanistic+routes+in+heterazolium+catalysis-promising+concepts+for+versatile+synthetic+methods.">Extending mechanistic routes in heterazolium catalysis-promising concepts for versatile synthetic methods.</a> Angew. Chem. Int. Ed. 44 (46), 7506-7510 (2005).</li><li>Schwarz, J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=N-Heterocyclic+carbenes,+part+25+-+Polymer-supported+carbene+complexes+of+palladium:+Well-defined,+air-stable,+recyclable+catalysts+for+the+Heck+reaction.">N-Heterocyclic carbenes, part 25 - Polymer-supported carbene complexes of palladium: Well-defined, air-stable, recyclable catalysts for the Heck reaction.</a> Chem. Eur. J. 6 (10), 1773-1780 (2000).</li><li>Akkoc, S., Gok, Y., Ilhan, I. O., Kayser, V. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=N-Methylphthalimide-substituted+benzimidazolium+salts+and+PEPPSI+Pd-NHC+complexes:+synthesis,+characterization+and+catalytic+activity+in+carbon-carbon+bond-forming+reactions.">N-Methylphthalimide-substituted benzimidazolium salts and PEPPSI Pd-NHC complexes: synthesis, characterization and catalytic activity in carbon-carbon bond-forming reactions.</a> Beilstein J. Org. Chem. 12, 81-88 (2016).</li><li>Karaca, E. O., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Palladium+complexes+with+tetrahydropyrimidin-2-ylidene+ligands:+Catalytic+activity+for+the+direct+arylation+of+furan,+thiophene,+and+thiazole+derivatives.">Palladium complexes with tetrahydropyrimidin-2-ylidene ligands: Catalytic activity for the direct arylation of furan, thiophene, and thiazole derivatives.</a> Organometallics. 34 (11), 2487-2493 (2015).</li><li>Ozdemir, I., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=N-Heterocyclic+carbene-palladium+catalysts+for+the+direct+arylation+of+pyrrole+derivatives+with+aryl+chlorides.">N-Heterocyclic carbene-palladium catalysts for the direct arylation of pyrrole derivatives with aryl chlorides.</a> Beilstein J. Org. Chem. 9, 303-312 (2013).</li><li>Senocak, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Synthesis,+crystal+structures,+magnetic+properties+and+Suzuki+and+Heck+coupling+catalytic+activities+of+new+coordination+polymers+containing+tetracyanopalladate(II)+anions.">Synthesis, crystal structures, magnetic properties and Suzuki and Heck coupling catalytic activities of new coordination polymers containing tetracyanopalladate(II) anions.</a> Polyhedron. 49 (1), 50-60 (2013).</li><li>Akkoc, S., Gok, Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Dichlorido(3-chloropyridine-N)+1,3-dialkylbenzimidazol-2-ylidene+palladium(II)+complexes:+Synthesis,+characterization+and+catalytic+activity+in+the+arylation+reaction.">Dichlorido(3-chloropyridine-N) 1,3-dialkylbenzimidazol-2-ylidene palladium(II) complexes: Synthesis, characterization and catalytic activity in the arylation reaction.</a> Inorg. Chim. Acta. 429, 34-38 (2015).</li><li>Akkoc, S., Gok, Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Catalytic+activities+in+direct+arylation+of+novel+palladium+N-heterocyclic+carbene+complexes.">Catalytic activities in direct arylation of novel palladium N-heterocyclic carbene complexes.</a> Appl. Organomet. Chem. 28 (12), 854-860 (2014).</li><li>Akkoc, S., Gok, Y., Ilhan, I. O., Kayser, V. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=In+situ+Generation+of+Efficient+Palladium+N-heterocyclic+Carbene+Catalysts+Using+Benzimidazolium+Salts+for+the+Suzuki-Miyaura+Cross-coupling+Reaction.">In situ Generation of Efficient Palladium N-heterocyclic Carbene Catalysts Using Benzimidazolium Salts for the Suzuki-Miyaura Cross-coupling Reaction.</a> Curr. Org. Synth. 13 (5), 761-766 (2016).</li></ol>

Les protocoles pour la synthèse et la purification de quatre sels de benzimidazolium et par la suite leurs complexes de NHC palladium ont été présentés délibérément dans le plus grand détail pour aider les jeunes scientifiques ou les nouveaux à maîtriser. Compte tenu de ce même objectif, les protocoles pour tester l&#39;activité catalytique des quatre complexes dans l&#39;arylation et les réactions de Suzuki-Miyaura ont également été présentés dans le plus grand détail. En outre, nous avons tenté de...

Les carbènes N- hétérocycliques (NHC) ont attiré beaucoup d&#39;attention, en particulier pour leur capacité à catalyser diverses réactions importantes telles que la métathèse, la création de furane, la polymérisation, l&#39;hydrosilylation, l&#39;hydrogénation, l&#39;arylation, le couplage croisé Suzuki-Miyaura et le couplage croisé Mizoroki-Heck 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 . Les NHC peuvent être couplés avec des métaux; De tels complexes métal-NHC ont été largement utilisés dans les réactions catalysées par des métaux de transition comme ligands auxiliaires et organocatalyseurs 12 , 13 , 14 , </Sup&gt; 15 , 16 . Généralement, ils sont extraordinairement stables contre l&#39;air, l&#39;humidité et la chaleur en conséquence des énergies de dissociation élevées des liaisons de coordination métal-carbone 17 . Ici, les protocoles pour la synthèse et la purification de quatre sels de benzimidazolium (composés 1 à 4 ) précédemment représentés et leurs complexes de NHC palladium (composés 5 à 8 respectivement) sont détaillés 18 . Les sels et les complexes ont été précédemment caractérisés en utilisant diverses techniques 18 . Étant donné que des composés similaires sont utilisés pour la catalyse de l&#39;arylation et des réactions de couplage croisé Suzuki-Miyaura 9 , 10 , 11 , les protocoles pour tester l&#39;activité catalytique des complexes dans l&#39;arylation et les réactions Suzuki-Miyaura sontLso détaillé. Il est important de noter que les protocoles de synthèse, de purification et de test de l&#39;activité catalytique des complexes sont suffisamment généraux pour permettre une adaptation facile aux nouveaux complexes NHC palladium.

<table border="1" fo:keep-together.within-page="1" fo:keep-with-next.within-page="always">
	<tbody>
		<tr>
			<td>1-chloro-4-nitrobenzene</td>
			<td>Sigma-Aldrich (Interlab A.S., USA)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>2,5-dimethoxyphenylboronic acid</td>
			<td>Sigma-Aldrich (Interlab A.S., USA)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>2-n-butylfuran</td>
			<td>Sigma-Aldrich (Interlab A.S., USA)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>2-n-butylthiophene</td>
			<td>Sigma-Aldrich (Interlab A.S., USA)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>3-chloropyridine</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>4-bromoacetophenone</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>4-bromoanisole</td>
			<td>Sigma-Aldrich (Interlab A.S., USA)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>4-chlorotoluene</td>
			<td>Sigma-Aldrich (Interlab A.S., USA)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>4-methoxy-1-chlorobenzene</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>4-tert-butylphenylboronic acid</td>
			<td>Sigma-Aldrich (Interlab A.S., USA)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Benzimidazole</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Bromobenzene</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Celite</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Dichloromethane</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Diethyl ether</td>
			<td>Sigma-Aldrich (Interlab A.S., USA)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Ethyl acetate</td>
			<td>Sigma-Aldrich (Interlab A.S., USA)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Ethyl alcohol</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Hexane</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Magnesium sulfate</td>
			<td>Scharlau (Barcelona, Spain)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>N,N-dimethylacetamide</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>N,N-dimethylformamide</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Palladium chloride</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Phenylboronic acid</td>
			<td>Sigma-Aldrich (Interlab A.S., USA)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Potassium acetate</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Potassium carbonate</td>
			<td>Scharlau (Barcelona, Spain)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Potassium hydroxide</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Silica gel</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Sodium tert-butoxide</td>
			<td>Merck (Darmstadt, Germany)</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Thianaphthene-2-boronic acid</td>
			<td>Sigma-Aldrich (Interlab A.S., USA)</td>
			<td></td>
			<td></td>
		</tr>
	</tbody>
</table>

palladium n-heterocyclic carbene complexes: synthesis from benzimidazolium salts and catalytic activity in carbon-carbon bond-forming reactions

Des protocoles détaillés et généralisés sont présentés pour la synthèse et la purification subséquente de quatre complexes de carbène N- hétérocyclique au palladium à partir de sels de benzimidazolium. Des protocoles détaillés et généralisés sont également présentés pour tester l&#39;activité catalytique de tels complexes dans l&#39;arylation et les réactions de couplage croisé de Suzuki-Miyaura. Des résultats représentatifs sont montrés pour l&#39;activité catalytique des quatre complexes dans l&#39;arylation et les réactions de type Suzuki-Miyaura. Pour chacune des réactions étudiées, au moins un des quatre complexes a réussi à catalyser la réaction, les qualifiant de candidats prometteurs pour la catalyse de nombreuses réactions de formation de liaison carbone-carbone. Les protocoles présentés sont assez généraux pour être adaptés pour la synthèse, la purification et l&#39;essai d&#39;activité catalytique de nouveaux complexes de carbène N- heterocycliques au palladium.

Les sels de benzimidazolium ( 1 à 4 ) ( figure 1 ) ont été synthétisés dans du DMF anhydre en utilisant des N- alkylbenzimidazoles et divers halogénures d&#39;alkyle, puis purifiés et caractérisés comme indiqué avant 18 , 24 . Ils étaient des matières solides blanches ou colorées et avaient des rendements allant de 62% à 97%. On a ensuite synth...

Watch this Scientific Journal Video about Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions at JoVE.com

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions

Des protocoles détaillés et généralisés sont présentés pour la synthèse et la purification subséquente de quatre complexes de carbène N- hétérocyclique au palladium à partir de sels de benzimidazolium. Les complexes ont été testés pour l&#39;activité catalytique dans l&#39;arylation et les réactions de Suzuki-Miyaura. Pour chaque réaction étudiée, au moins un des quatre complexes a catalysé avec succès la réaction.

Palladium<em&gt; N</em&gt; - Complexes de carbène hétérocyclique: synthèse des sels de benzimidazolium et activité catalytique dans les réactions de formation de liaison carbone-carbone

Detailed and generalized protocols are presented for the synthesis and subsequent purification of four palladium N-heterocyclic carbene complexes from ...

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Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions

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Titanium (IV) and vanadium (V) complexes are highly potent anticancer agents. A challenge in their synthesis refers to their hydrolytic instability; ...

Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols

Retropinacol / Croix-pinacol réactions de couplage - Un accès catalytique de 1,2-diols asymétriques

Unsymmetrical 1,2-diols are hardly accessible by reductive pinacol coupling processes. A successful execution of such a transformation is bound to a clear ...

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions

Mizoroki-Heck réactions de couplage croisé catalysées par Dichloro {bis [1,1 &#39;, 1&#39;&#39; - (phosphinetriyl) tripiperidine]} palladium Sous légère réaction Conditions

Dichloro-bis(aminophosphine) complexes of palladium with the general formula of [(P{(NC5H10)3-n(C6H11)n})2Pd(Cl)2] (where n = 0-2), belong to a new family ...

Synthesis and Catalytic Performance of Gold Intercalated in the Walls of Mesoporous Silica

Synthèse et performance catalytique de l&#39;or intercalé dans les murs de silice mésoporeuse

As a promising catalytically active nano reactor, gold nanoparticles intercalated in mesoporous silica (GMS) were successfully synthesized and properties ...

Metal-free Synthesis of Ynones from Acyl Chlorides and Potassium Alkynyltrifluoroborate Salts

Synthèse sans métal de Ynones de Acyl chlorures et du potassium Alkynyltrifluoroborate Sels

Ynones are a valuable functional group and building block in organic synthesis. Ynones serve as a precursor to many important organic functional groups ...

The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes

The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes

La synthèse, la caractérisation et la réactivité d&#39;une série de ruthénium<em&gt; N</em&gt; -triphos<sup&gt; Ph</sup&gt; Complexes

Herein we report the synthesis of a tridentate phosphine ligand N(CH2PPh2)3 (N-triphosPh) (1) via a phosphorus based Mannich reaction of the ...

Laboratory Production of Biofuels and Biochemicals from a Rapeseed Oil through Catalytic Cracking Conversion

Laboratoire de production de biocarburants et produits biochimiques à partir d&#39;une huile de colza par Catalytic Cracking Conversion

The work is based on a reported study which investigates the processability of canola oil (bio-feed) in the presence of bitumen-derived heavy gas oil ...

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine

Réactions de Cascade enzymatique pour la synthèse des aminoalcools chiraux de L-lysine

Amino alcohols are versatile compounds with a wide range of applications. For instance, they have been used as chiral scaffolds in organic synthesis. ...

Chemical Precipitation Method for the Synthesis of Nb2O5 Modified Bulk Nickel Catalysts with High Specific Surface Area

Chemical Precipitation Method for the Synthesis of Nb2O5 Modified Bulk Nickel Catalysts with High Specific Surface Area

Méthode de précipitation chimique pour la synthèse de Nb2O5 modifiée catalyseurs Nickel en vrac avec le haute surface spécifique

We demonstrate a method for the synthesis of NixNb1-xO catalysts with sponge-like and fold-like nanostructures. By varying the Nb:Ni ratio, a series of ...