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DOI :
10.3791/55724-v
•
6:51 min
August 10th, 2018
Chapters
0:04
Title
0:48
Tail Vein Injection of AAV-miRNA Plasmid
2:14
Behavioral Assays: Hanging Wire and Foot Print Assay
3:30
Tissue Harvest
4:27
Results: Treatment of SBMA Mice with miRNA
5:59
Conclusion
在这里, 我们描述了 microRNA 使用重组腺相关病毒9型在小鼠神经肌肉疾病模型中的交付。小鼠的单个外围管理导致肌肉和运动神经元的持续 miRNA 过度表达, 为研究 miRNA 功能和体内的治疗潜力提供了机会。
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