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DOI :
10.3791/55803-v
July 21st, 2017
Chapters
0:05
Title
0:56
Formulation of siRNA Nanocarriers
11:07
Conclusion
9:35
Results: Prediction and Spatiotemporal Control of Gene Silencing
2:09
Measuring siRNA Release Using Gell Electrophoresis
4:57
Measuring siRNA Release Using Fluorescence Correlation Spectroscopy (FCS)
6:12
Cell Culture and In Vitro siRNA Delivery
8:15
Controlling Gene Silencing in a Spatiotemporal Manner
本発明者らは、検出可能なオフターゲット効果なしに遺伝子サイレンシングのより効率的な時空間制御のために光反応性ブロックコポリマーを使用する新規な方法を提示する。さらに、遺伝子発現の変化は、単純なsiRNA放出アッセイおよび単純な運動モデルを用いて予測することができる。
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