Name: ultrasound cyclo plasty in eyes with glaucoma
Uploaded: 2018-01-26T12:30:00
Description: Watch this Scientific Journal Video about Ultrasound Cyclo Plasty in Eyes with Glaucoma at JoVE.com

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Alle deltagere der både mundtlig og skriftlig informeret samtykke før nogen studere procedure. Protokollen af undersøgelsen blev gennemført i overensstemmelse med Helsinki-erklæringen og blev godkendt af det etiske udvalg for human forskning af S.Orsola-Malpighi Universitetshospital.
1. Præoperative procedurer og oftalmologisk vurderingen
<ol><li>Test afstand og nær bedste korrigerede synsstyrke (BCVA).</li>
	<li>Evaluere den forreste segment af øjet ved hjælp af en spaltede lampe b...

<ol>
	<li>Congdon, N., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Causes+and+prevalence+of+visual+impairment+among+adults+in+the+United+States.">Causes and prevalence of visual impairment among adults in the United States.</a> Arch Ophthalmol. 122 (4), 477-485 (2004).</li><li>Floriani, I., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Health-related+quality+of+life+in+patients+with+primary+open-angle+glaucoma.+An+Italian+multicentre+observational+study.">Health-related quality of life in patients with primary open-angle glaucoma. An Italian multicentre observational study.</a> Acta Ophthalmol. , (2015).</li><li>Traverso, C. E., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Direct+costs+of+glaucoma+and+severity+of+the+disease:+a+multinational+long+term+study+of+resource+utilisation+in+Europe.">Direct costs of glaucoma and severity of the disease: a multinational long term study of resource utilisation in Europe.</a> Br J Ophthalmol. 89 (10), 1245-1249 (2005).</li><li>European Glaucoma Society. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Terminology+and+guidelines+for+glaucoma.">Terminology and guidelines for glaucoma.</a> EGS Guidelines. , (2014).</li><li>De Roetth, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Cryosurgery+for+the+treatment+of+glaucoma.">Cryosurgery for the treatment of glaucoma.</a> Trans Am Ophthalmol Soc. 63, 189-204 (1965).</li><li>Maus, M., Katz, L. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Choroidal+detachment,+flat+anterior+chamber,+and+hypotony+as+complications+of+neodymium:+YAG+laser+cyclophotocoagulation.">Choroidal detachment, flat anterior chamber, and hypotony as complications of neodymium: YAG laser cyclophotocoagulation.</a> Ophthalmology. 97 (1), 69-72 (1990).</li><li>Uram, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Ophthalmic+laser+microendoscope+ciliary+process+ablation+in+the+management+of+neovascular+glaucoma.">Ophthalmic laser microendoscope ciliary process ablation in the management of neovascular glaucoma.</a> Ophthalmology. 99 (12), 1823-1828 (1992).</li><li>al-Ghamdi, S., al-Obeidan, S., Tomey, K. F., al-Jadaan, I. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Transscleral+neodymium:YAG+laser+cyclophotocoagulation+for+end-stage+glaucoma,+refractory+glaucoma,+and+painful+blind+eyes.">Transscleral neodymium:YAG laser cyclophotocoagulation for end-stage glaucoma, refractory glaucoma, and painful blind eyes.</a> Ophthalmic Surg. 24 (8), 526-529 (1993).</li><li>Kosoko, O., Gaasterland, D. E., Pollack, I. P., Enger, C. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Long-term+outcome+of+initial+ciliary+ablation+with+contact+diode+laser+transscleral+cyclophotocoagulation+for+severe+glaucoma.+The+Diode+Laser+Ciliary+Ablation+Study+Group.">Long-term outcome of initial ciliary ablation with contact diode laser transscleral cyclophotocoagulation for severe glaucoma. The Diode Laser Ciliary Ablation Study Group.</a> Ophthalmology. 103 (8), 1294-1302 (1996).</li><li>Hamard, P., Gayraud, J. M., Kopel, J., Valtot, F., Quesnot, S., Hamard, H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Treatment+of+refractory+glaucomas+by+transscleral+cyclophotocoagulation+using+semiconductor+diode+laser.+Analysis+of+50+patients+followed-up+over+19+months.">Treatment of refractory glaucomas by transscleral cyclophotocoagulation using semiconductor diode laser. Analysis of 50 patients followed-up over 19 months.</a> J Fr Ophthalmol. 20 (2), 125-133 (1997).</li><li>Sabri, K., Vernon, S. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Scleral+perforation+following+trans-scleral+cyclodiode.">Scleral perforation following trans-scleral cyclodiode.</a> Br J Ophthalmol. 83 (4), 502-503 (1999).</li><li>Vernon, S. A., Koppens, J. M., Menon, G. J., Negi, A. K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Diode+laser+cycloablation+in+adult+glaucoma:+long-term+results+of+a+standard+protocol+and+review+of+current+literature.">Diode laser cycloablation in adult glaucoma: long-term results of a standard protocol and review of current literature.</a> Clin Experiment Ophthalmol. 34 (5), 411-420 (2006).</li><li>Aptel, F., Charrel, T., Palazzi, X., Chapelon, J. Y., Denis, P., Lafon, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Histologic+effects+of+a+new+device+for+high-intensity+focused+ultrasound+cyclocoagulation.">Histologic effects of a new device for high-intensity focused ultrasound cyclocoagulation.</a> Invest Ophthalmol Vis Sci. 51 (10), 5092-5098 (2010).</li><li>Aptel, F., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Miniaturized+high-intensity+focused+ultrasound+device+in+patients+with+glaucoma:+a+clinical+pilot+study.">Miniaturized high-intensity focused ultrasound device in patients with glaucoma: a clinical pilot study.</a> Invest Ophthalmol Vis Sci. 52 (12), 8747-8753 (2011).</li><li>Aptel, F., Dupuy, C., Rouland, J. F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Treatment+of+refractory+open-angle+glaucoma+using+ultrasonic+circular+cyclocoagulation:+a+prospective+case+series.">Treatment of refractory open-angle glaucoma using ultrasonic circular cyclocoagulation: a prospective case series.</a> Curr Med Res Opin. 30 (8), 1599-1605 (2014).</li><li>Aptel, F., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Short-+and+long-term+effects+on+the+ciliary+body+and+the+aqueous+outflow+pathways+of+high-intensity+focused+ultrasound+cyclocoagulation.">Short- and long-term effects on the ciliary body and the aqueous outflow pathways of high-intensity focused ultrasound cyclocoagulation.</a> Ultrasound Med Biol. 40 (9), 2096-2106 (2014).</li><li>Charrel, T., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Development+of+a+miniaturized+HIFU+device+for+glaucoma+treatment+with+conformal+coagulation+of+the+ciliary+bodies.">Development of a miniaturized HIFU device for glaucoma treatment with conformal coagulation of the ciliary bodies.</a> Ultrasound Med Biol. 37 (5), 742-754 (2011).</li><li>Aptel, F., Lafon, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Therapeutic+applications+of+ultrasound+in+ophthalmology.">Therapeutic applications of ultrasound in ophthalmology.</a> Int J Hyperthermia. 28 (4), 405-418 (2012).</li><li>Denis, P., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Cyclocoagulation+of+the+ciliary+bodies+by+high-intensity+focused+ultrasound:+a+12-month+multicenter+study.">Cyclocoagulation of the ciliary bodies by high-intensity focused ultrasound: a 12-month multicenter study.</a> Invest Ophthalmol Vis Sci. 56 (2), 1089-1096 (2015).</li><li>Aptel, F., Lafon, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Treatment+of+glaucoma+with+high+intensity+focused+ultrasound.">Treatment of glaucoma with high intensity focused ultrasound.</a> Int J Hyperthermia. 31 (3), 292-301 (2015).</li><li>Giannaccare, G., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=High-intensity+focused+ultrasound+treatment+in+patients+with+refractory+glaucoma.">High-intensity focused ultrasound treatment in patients with refractory glaucoma.</a> Graefes Arch Clin Exp Ophthalmol. 255 (3), 599-605 (2017).</li><li>Mastropasqua, R., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Uveo-scleral+outflow+pathways+after+ultrasonic+cyclocoagulation+in+refractory+glaucoma:+an+anterior+segment+optical+coherence+tomography+and+in+vivo+confocal+study.">Uveo-scleral outflow pathways after ultrasonic cyclocoagulation in refractory glaucoma: an anterior segment optical coherence tomography and in vivo confocal study.</a> Br J Ophthalmol. 100 (12), 1668-1675 (2016).</li><li>Melamed, S., Goldenfeld, M., Cotlear, D., Skaat, A., Moroz, I. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=High-intensity+focused+ultrasound+treatment+in+refractory+glaucoma+patients:+results+at+1+year+of+prospective+clinical+study.">High-intensity focused ultrasound treatment in refractory glaucoma patients: results at 1 year of prospective clinical study.</a> Eur J Ophthalmol. 25 (6), 483-489 (2015).</li><li>Aptel, F., Denis, P., Rouland, J. F., Renard, J. P., Bron, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Multicenter+clinical+trial+of+high-intensity+focused+ultrasound+treatment+in+glaucoma+patients+without+previous+filtering+surgery.">Multicenter clinical trial of high-intensity focused ultrasound treatment in glaucoma patients without previous filtering surgery.</a> Acta Ophthalmol. 94 (5), e268-e277 (2016).</li><li>Coleman, D. J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Therapeutic+ultrasound+in+the+treatment+of+glaucoma.+II.+Clinical+applications.">Therapeutic ultrasound in the treatment of glaucoma. II. Clinical applications.</a> Ophthalmology. 92 (3), 347-353 (1985).</li><li>Valtot, F., Kopel, J., Haut, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Treatment+of+glaucoma+with+high+intensity+focused+ultrasound.">Treatment of glaucoma with high intensity focused ultrasound.</a> Int Ophthalmol. 13 (1-2), 167-170 (1989).</li><li>Burgess, S. E., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Treatment+of+glaucoma+with+high-intensity+focused+ultrasound.">Treatment of glaucoma with high-intensity focused ultrasound.</a> Ophthalmology. 93 (6), 831-838 (1986).</li><li>Chen, J., Cohn, R. A., Lin, S. C., Cortes, A. E., Alvarado, J. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Endoscopic+photocoagulation+of+the+ciliary+body+for+treatment+of+refractory+glaucomas.">Endoscopic photocoagulation of the ciliary body for treatment of refractory glaucomas.</a> Am J Ophthalmol. 124 (6), 787-796 (1997).</li><li>Iliev, M. E., Gerber, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Long-term+outcome+of+trans-scleral+diode+laser+cyclo-photocoagulation+in+refractory+glaucoma.">Long-term outcome of trans-scleral diode laser cyclo-photocoagulation in refractory glaucoma.</a> Br J Ophthalmol. 91 (12), 1631-1635 (2007).</li></ol>

Glaukom er en kronisk fremadskridende sygdom, der påvirker synsnerven som nye effektive behandlinger er nødvendige for at forbedre langsigtet prognose. Reduktion af IOP er stadig betragtes som den eneste effektive terapi for at forhindre eller forsinke visuelle felt tab, i øjnene både med og uden forhøjet IOP3.
UCP er en ny ikke-incisional cyclodestructive procedure, der kan sænke IOP, optræder på to forskellige måder: det reducerer den vandige humor indstrømn...

Glaukom repræsenterer en af de største årsager til blindhed globalt, der berører omkring 100 millioner mennesker1. Det er en optisk neuropati genereret af den progressive degeneration af nerve fibre, der konvergerer på synsnerven, funktionelt medførende et fald af synsfeltet, der kan udvikle sig til synshandicap og til sidst blindhed uden tilstrækkelig behandling2.
Forhøjede IOP er stadig betragtes som den vigtigste risikofaktor for grøn stær debut og progression, og i øjeblikket parameteren kun behandles at reducere visuelle felt tab3. IOP reduktion kan opnås ved både at reducere produktionen af kammervæske og/eller øge sit udløb gennem trabekelværket ved brug af aktuelle eller systemiske lægemidler, laser eller kirurgi3,4. Mange fysiske processer har allerede indført for at fremkalde koagulation nekrose af ciliare efter opvarmning eller frysning5,6,7,8,9, 10,11,12. Imidlertid manglen på selektivitet for målvæv og uforudsigelige dosis / effekt-forholdet at reducere IOP begrænser deres brug kun til øjne med glaukom resistente over for konventionelle medicinske og kirurgiske behandlinger4.
I de sidste år, en ny indretning, benævnt UCP, der beskæftiger højintensive fokuseret ultralyd (HIFU) er udviklet med henblik på at overvinde begrænsningerne af traditionel cyclodestructive teknikker ved at opnå en mere selektiv koagulation af den corpus ciliare og undgå eventuelle skader på de tilstødende okulær strukturer13,14,15,16,17,18,19, 20 , 21. Desuden stimulering af supra choroidal og trans-scleral dele af uveo-scleral udstrømning pathway har for nylig foreslået som en mulig tillægsbehandling mekanisme af proceduren for at reducere IOP22. Til dato, er syv større kliniske undersøgelser blevet gennemført ved hjælp af UCP enhed i forskellige typer og sværhedsgraden kvaliteter af glaukom, demonstrere effektiviteten og sikkerheden af denne ikke-incisional procedure14,15, 19,20,21,22,23,24.
Formålet med denne undersøgelse er at beskrive de ovennævnte procedure i detaljer, for at udbrede kendskabet til sin introduktion til det videnskabelige medicinske samfund og give nyttige tips og tricks til kirurger, der ønsker at nærme sig dette nye felt.

<table>
	<tbody>
		<tr>
			<td>BM 900 Slit Lamp Biomioscropy</td>
			<td>Haag-Streit, Koeniz, Switzerland</td>
			<td>BM 900</td>
			<td>Slit Lamp Biomiscroscopy</td>
		</tr>
		<tr>
			<td>G-4 Four-Mirror Glass Gonio Lens</td>
			<td>Volk Optical Inc., Mentor, OH, USA</td>
			<td>#VG4</td>
			<td>Contact lens for gonioscopy</td>
		</tr>
		<tr>
			<td>78D Non Contact Slit Lamp Lens</td>
			<td>Volk Optical Inc., Mentor, OH, USA</td>
			<td>#V78C</td>
			<td>Non contact slit lamp lens</td>
		</tr>
		<tr>
			<td>HospiFluo strips</td>
			<td>AIESI Hospital Service S.a.s., Napoli, Italy</td>
			<td>AHS129</td>
			<td>Fluorescein sterile disposable strips</td>
		</tr>
		<tr>
			<td>AT 900 Goldmann Applanation Tonometer</td>
			<td>Haag-Streit, Koeniz, Switzerland</td>
			<td>AT 900</td>
			<td>Goldmann applanation tonometer</td>
		</tr>
		<tr>
			<td>Lenstar LS900</td>
			<td>Haag-Streit, Koeniz, Switzerland</td>
			<td>LS900</td>
			<td>Optical biometer</td>
		</tr>
		<tr>
			<td>Pilocarpina 2% eye drops</td>
			<td>Farmigea, Pisa, Italy</td>
			<td>S01EB01</td>
			<td>Miotic eye drops</td>
		</tr>
		<tr>
			<td>Mepivacaina 20mg/ml injectable solution</td>
			<td>Angelini, Roma, Italy</td>
			<td>N01BB03</td>
			<td>Local anesthetic for injection</td>
		</tr>
		<tr>
			<td>Naropina 10mg/ml injectable solution</td>
			<td>AstraZeneca, Milano, Italy</td>
			<td>N01BB09</td>
			<td>Local anesthetic for injection</td>
		</tr>
		<tr>
			<td>Oftasteril 5% eye drops</td>
			<td>Alfa Intes, Napoli, Italy</td>
			<td>S01AX18</td>
			<td>5% povidone-iodine eye drops</td>
		</tr>
		<tr>
			<td>EyeOP1</td>
			<td>Eye Tech Care, Rillieux-la-Pape, France</td>
			<td></td>
			<td>UCP device</td>
		</tr>
		<tr>
			<td>BSS (balanced salt solution)</td>
			<td>Alcon Inc., Forth Worth, TX, USA</td>
			<td>0065-1795-04</td>
			<td>Sterile irrigating solution</td>
		</tr>
		<tr>
			<td>Tobradex eye drops</td>
			<td>Alcon Italia Spa, Milano, Italy</td>
			<td>S01CA01</td>
			<td>Antibiotic and steroid eye drops</td>
		</tr>
	</tbody>
</table>

ultrasound cyclo plasty in eyes with glaucoma

Glaukom er en kronisk sygdom forårsaget af den progressive degeneration af de optiske nerve fibre, hvilket resulterer i nedsat synsfelt, der kan føre til svære synshandicap, og til sidst blindhed. Dette manuskript beskriver en simpel, kirurg-venlige, ikke-incisional teknik, opkaldt ultralyd Cyclo plastik (UCP), for at reducere intraokulært tryk (IOP) i grøn stær patienter. Teknikken, der bestemmer en selektiv koagulation nekrose af ciliare; Derudover er stimulation af supra choroidal og trans-scleral dele af uveo-scleral udstrømning pathway foreslået for nylig. UCP viser flere tekniske forbedringer i ultralyd teknologi sammenlignet med tidligere teknikker, give mere præcis fokusering på pulszonen. Proceduren udføres i operationsstuen under peribulbar anæstesi. Kort, kobling kegle er sat i kontakt med øjet og ring sonde, der indeholder seks piezoelektriske transducere, som producerer ultralyd bjælker, indsættes inde i den. Deres korrekt centrering over okulær overflade er et afgørende skridt for den korrekte målretning af ciliare. Sterile afbalanceret saltopløsning bruges til at udfylde de tomme pladser for at sikre ultralyd akustiske formering. Kirurgiske behandling består i sekventiel automatisk aktivering af hver af seks transducere, for en samlet varighed på mindre end 3 min. Patienten forlader sygehuset 1 h efter proceduren med den behandlede øje lappet. I den foreliggende undersøgelse, 10 patienter med åbenvinklet glaukom blev fulgt op i mindst 12 måneder efter indgrebet. IOP blev reduceret med hvert interval i forhold til præoperativ, samt antallet af hypotensive medicin. Tyve procent af patienterne reagerer ikke på behandling, og behov for efterfølgende kirurgi til bedre at styre IOP. Behandling tolerabilitet var god, med ingen tilfælde af hypotony eller phthisis. UCP-proceduren er enklere, hurtigere, mere sikker og mindre indgribende end traditionelle cyclodestructive procedurer med lignende resultater i at reducere IOP.

Ti øjne af 10 patienter (6 mænd og 4 kvinder, mener alder 64.9 ± 13,7 år, vifte 39-80 år) ramt af åben-vinkel glaukom blev behandlet med UCP enhed ifølge den teknik beskrevet ovenfor. Behandling eksponeringstid blev 4 s for 2 patienter, 6 Sørensen for 4 patienter, og 8 s for 4 patienter. Før operationen, betyder IOP var 24,8 ± 9.6 mmHg (gennemsnit ± standardafvigelse), mens det gennemsnitlige antal daglige hypotensive dråber var 3,9 ± 1,0 og det gennemsnitlige antal daglige a...

Watch this Scientific Journal Video about Ultrasound Cyclo Plasty in Eyes with Glaucoma at JoVE.com

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Glaukom er en kronisk sygdom med progressive degeneration af optiske nervefibre resulterer i nedsat synsfelt. Forhøjet intraokulært tryk betragtes som det vigtigste og den kun behandlelige risikofaktor. Dette manuskript beskriver en simpel, kirurg-venlige, ikke-incisional teknik, opkaldt ultralyd Cyclo plastik, til reduktion af intraokulært tryk i grøn stær patienter.

Ultralyd Cyclo plastik i øjnene med glaukom

Glaucoma is a chronic disease caused by the progressive degeneration of the optical nerve fibers, resulting in decreased visual field that can lead to ...

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Performing Behavioral Tasks in Subjects with Intracranial Electrodes

Udførelse Adfærdsmæssige opgaver hos forsøgspersoner med Intrakranielle elektroder

Patients having stereo-electroencephalography (SEEG) electrode, subdural grid or depth electrode implants have a multitude of electrodes implanted in ...

How to Study Placebo Responses in Motion Sickness with a Rotation Chair Paradigm in Healthy Participants

Sådan Undersøgelse Placebo Svar i Motion Sickness med Rotation Chair Paradigm Hos raske deltagere

Placebo responses occur in every medical intervention when patients or participants expect to receive an effective treatment to relieve symptoms. However, ...

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Test Sensorisk og multisensoriske funktion hos børn med autismespektrumforstyrrelser

In addition to impairments in social communication and the presence of restricted interests and repetitive behaviors, deficits in sensory processing are ...

Ultrasound Images of the Tongue: A Tutorial for Assessment and Remediation of Speech Sound Errors

Ultralyd Billeder af Tongue: En Tutorial for Evaluering og oprydning af Speech Sound fejl

Diagnostic ultrasound imaging has been a common tool in medical practice for several decades. It provides a safe and effective method for imaging ...

Profiling Anti-Neu5Gc IgG in Human Sera with a Sialoglycan Microarray Assay

Profilering Anti-Neu5Gc IgG i humant serum med en Sialoglycan Microarray Assay

Cells are covered with a cloak of carbohydrate chains (glycans) that is commonly altered in cancer and that includes variations in sialic acid (Sia) ...