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DOI :
10.3791/56401-v
December 20th, 2017
Chapters
0:05
Title
0:56
Overlapping Peptide (OLP) Library Generation and T Cell Priming with OLP Pool-pulsed Dendritic Cells (DCs) Protocol
3:43
Re-stimulation of OLP Pool-primed CD8+ T Cells Using Macrophages Pulsed with the OLP Pool
6:19
Results: Identification of a 9-mer Qa-1 Epitope in Myelin Oligodendrocyte Glycoprotein (MOG)
7:32
Conclusion
Qa-1 (HLA) 属于一组经典主要组织相容性复杂的1b 分子。免疫 Qa-1-binding 表位已表明, 以加强组织特异性免疫调节和改善一些自身免疫性疾病。在此, 我们描述一个重叠的肽库策略, 以确定 Qa-1 表位的蛋白质。
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