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DOI :
10.3791/56795-v
January 25th, 2018
Chapters
0:05
Title
1:17
Measurement of Luciferase Reporter Signals, which Correspond to γ-Secretase Cleavage of APP-C99 (CG cells) or NΔE (NG cells)
3:42
Quantification of γ-Secretase Activity
4:40
Results: Treatments with CL-387, 785 can Differentially Promote the Processing of APP-C99 by γ-Secretase without Affecting Notch Cleavage
6:05
Conclusion
我々 は正常に 2 つの基質特異的 γ-セクレターゼ アッセイを生成されます。ここに提示両方のセルベースのアッセイは、ホタル ルシフェラーゼ レポーターのアウトプットを介して γ セクレターゼ酵素を定量化する設計されています。
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