心筋細胞のシステム生物学における細胞構造の役割を研究する心筋細胞の構造的に現実的な有限要素の幾何学的なモデルを作成します。
April 18th, 2018
•Vijay Rajagopal1,2,3, Gregory Bass2,3, Shouryadipta Ghosh1,2,3, Hilary Hunt2,4, Cameron Walker5, Eric Hanssen6, Edmund Crampin2,3,4,7,8, Christian Soeller9
1Cell Structure and Mechanobiology Group, University of Melbourne, 2Systems Biology Laboratory, Melbourne School of Engineering, University of Melbourne, 3Department of Biomedical Engineering, University of Melbourne, 4School of Mathematics and Statistics, Faculty of Science, University of Melbourne, 5Department of Engineering Science, University of Auckland, 6Advanced Microscopy Facility, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 7ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, University of Melbourne, 8School of Medicine, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, 9Living Systems Institute, University of Exeter
このプロトコルでは、電子顕微鏡や共焦点顕微鏡画像から心筋細胞の細胞内構造の空間的有限要素モデルを作成する手法について説明します。カルシウム シグナルと生体エネルギー転換の事例を使用してこの空間詳細モデルの力を発揮します。
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