Name: application of end-to-end anastomosis in robotic central pancreatectomy
Uploaded: 2018-06-02T13:30:00
Description: Watch this Scientific Journal Video about Application of End-to-end Anastomosis in Robotic Central Pancreatectomy at JoVE.com

Los autores no tienen ninguna agradecimientos.

Consentimiento informado escrito fue obtenido del paciente para la publicación de este informe y los videos y las imágenes que acompaña.
1. preoperatorio preparación
<ol><li>Evaluar cuidadosamente las imágenes preoperatorias de CT o MRI para la ubicación exacta del tumor y su relación con los tejidos circundantes.</li>
	<li>Dar al paciente una dieta blanda un día antes de la operación y comenzar el ayuno a la medianoche antes de la operación.</li>
	<li>Colocar al paciente en la mes...

<ol>
	<li>Goudard, Y., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Reappraisal+of+central+pancreatectomy+a+12-year+single-center+experience.">Reappraisal of central pancreatectomy a 12-year single-center experience.</a> JAMA Surg. 149 (4), 356-363 (2014).</li><li>Iacono, C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Systematic+review+of+central+pancreatectomy+and+meta-analysis+of+central+versus+distal+pancreatectomy.">Systematic review of central pancreatectomy and meta-analysis of central versus distal pancreatectomy.</a> Br J Surg. 100 (7), 873-885 (2013).</li><li>Sperti, C., Beltrame, V., Milanetto, A. C., Moro, M., Pedrazzoli, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Parenchyma-sparing+pancreatectomies+for+benign+or+border-line+tumors+of+the+pancreas.">Parenchyma-sparing pancreatectomies for benign or border-line tumors of the pancreas.</a> World Journal of Gastrointestinal Oncology. 2 (6), 272-281 (2010).</li><li>Kim, D. H., Kang, C. M., Lee, W. J., Chi, H. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Robotic+central+pancreatectomy+with+pancreaticogastrostomy+(transgastric+approach)+in+a+solid+pseudopapillary+tumor+of+the+pancreas.">Robotic central pancreatectomy with pancreaticogastrostomy (transgastric approach) in a solid pseudopapillary tumor of the pancreas.</a> Hepato-gastroenterology. 58 (110-111), 1805-1808 (2011).</li><li>Addeo, P., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Robotic+central+pancreatectomy+with+stented+pancreaticogastrostomy:+operative+details.">Robotic central pancreatectomy with stented pancreaticogastrostomy: operative details.</a> The international journal of medical robotics + computer assisted surgery: MRCAS. 7 (3), 293-297 (2011).</li><li>Abood, G. J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Robotic-assisted+minimally+invasive+central+pancreatectomy:+technique+and+outcomes.">Robotic-assisted minimally invasive central pancreatectomy: technique and outcomes.</a> J Gastrointest Surg. 17 (5), 1002-1008 (2013).</li><li>Schwarz, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Total+Laparoscopic+Central+Pancreatectomy+with+Pancreaticogastrostomy+for+High-Risk+Cystic+Neoplasm.">Total Laparoscopic Central Pancreatectomy with Pancreaticogastrostomy for High-Risk Cystic Neoplasm.</a> Annals of surgical oncology. 23 (3), 1035 (2016).</li><li>Topal, B., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Pancreaticojejunostomy+versus+pancreaticogastrostomy+reconstruction+after+pancreaticoduodenectomy+for+pancreatic+or+periampullary+tumours:+a+multicentre+randomised+trial.">Pancreaticojejunostomy versus pancreaticogastrostomy reconstruction after pancreaticoduodenectomy for pancreatic or periampullary tumours: a multicentre randomised trial.</a> The Lancet Oncology. 14 (7), 655-662 (2013).</li><li>Lemaire, E., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Functional+and+morphological+changes+in+the+pancreatic+remnant+following+pancreaticoduodenectomy+with+pancreaticogastric+anastomosis.">Functional and morphological changes in the pancreatic remnant following pancreaticoduodenectomy with pancreaticogastric anastomosis.</a> Br J Surg. 87 (4), 434-438 (2000).</li><li>Rault, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Pancreaticojejunal+Anastomosis+Is+Preferable+to+Pancreaticogastrostomy+after+Pancreaticoduodenectomy+for+Longterm+Outcomes+of+Pancreatic+Exocrine+Function.">Pancreaticojejunal Anastomosis Is Preferable to Pancreaticogastrostomy after Pancreaticoduodenectomy for Longterm Outcomes of Pancreatic Exocrine Function.</a> Journal of the American College of Surgeons. 201 (2), 239-244 (2005).</li><li>Lai, E. C., Tang, C. N. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Robotic+distal+pancreatectomy+versus+conventional+laparoscopic+distal+pancreatectomy:+a+comparative+study+for+short-term+outcomes.">Robotic distal pancreatectomy versus conventional laparoscopic distal pancreatectomy: a comparative study for short-term outcomes.</a> Frontiers of medicine. 9 (3), 356-360 (2015).</li><li>Konstantinidis, I. T., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Robotic+total+pancreatectomy+with+splenectomy:+technique+and+outcomes.">Robotic total pancreatectomy with splenectomy: technique and outcomes.</a> Surg Endosc. , (2017).</li><li>Liu, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+surgical+outcomes+of+robot-assisted+laparoscopic+pancreaticoduodenectomy+versus+laparoscopic+pancreaticoduodenectomy+for+periampullary+neoplasms:+a+comparative+study+of+a+single+center.">The surgical outcomes of robot-assisted laparoscopic pancreaticoduodenectomy versus laparoscopic pancreaticoduodenectomy for periampullary neoplasms: a comparative study of a single center.</a> Surg Endosc. 31 (6), 2380-2386 (2017).</li><li>Lui, R., Zhao, G., Yin, Z., Zhao, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Robotic+enucleation+for+pancreatic+neoplasm+with+interposition+repair+of+the+main+pancreatic+duct:+a+case+report.">Robotic enucleation for pancreatic neoplasm with interposition repair of the main pancreatic duct: a case report.</a> Chinese Journal of Laparoscopic Surgery. 9 (6), 373-374 (2016).</li><li>Ehrhardt, O. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Ueber+Resektionen+am+Pankreas1.">Ueber Resektionen am Pankreas1.</a> DMW-Deutsche Medizinische Wochenschrift. 34, 595-597 (1908).</li><li>Wolk, S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Evaluation+of+central+pancreatectomy+and+pancreatic+enucleation+as+pancreatic+resections--A+comparison.">Evaluation of central pancreatectomy and pancreatic enucleation as pancreatic resections--A comparison.</a> Int J Surg. 22, 118-124 (2015).</li><li>Ishii, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Remnant+pancreas+reconstruction+with+duct-to-duct+anastomosis+after+middle+pancreatectomy:+a+report+of+two+cases.">Remnant pancreas reconstruction with duct-to-duct anastomosis after middle pancreatectomy: a report of two cases.</a> Hepato-gastroenterology. 62 (137), 190-194 (2015).</li><li>Di Benedetto, F., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Meso-pancreatectomy:+new+surgical+technique+for+Wirsung+reconstruction.">Meso-pancreatectomy: new surgical technique for Wirsung reconstruction.</a> J Am Coll Surg. 214 (2), 1-4 (2012).</li><li>Oida, Y., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=End-to-end+anastomosis+after+medial+pancreatectomy+for+tumor.">End-to-end anastomosis after medial pancreatectomy for tumor.</a> Hepato-gastroenterology. 54 (76), 1266-1268 (2007).</li><li>Ramesh, H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=End-to-end+anastomosis+of+pancreas.">End-to-end anastomosis of pancreas.</a> Surgery. 131 (6), 691-693 (2002).</li><li>Kang, C. 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Tumores malignos en el cuello del páncreas y la parte proximal del cuerpo pancreático son a menudo tratados con pancreaticoduodenectomy o Pancreatectomía distal. Sin embargo, para los tumores potenciales malos benignos o baja en esos sitios, la pancreatoduodenectomía estándar o Pancreatectomía distal retirará excesiva tejidos normales y lesiones excesivas. Por lo tanto, la Pancreatectomía central o enucleación pancreática, conocido como "conservadora de parénquima Pancreatectomía", se convierte en una opción...

Pancreatectomía central cada vez más se realiza para el tratamiento de tumores potenciales benignos o malignos bajo situado en el cuello pancreático o la parte proximal del cuerpo pancreático1. En comparación con la Pancreaticoduodenectomía o Pancreatectomía distal, Pancreatectomía central reseca menos los tejidos y conserva más pancreáticas parénquima y función. Actualmente, los principales enfoques para la reconstrucción de páncreas son exceso de coser el muñón pancreático cefálico y realizando un pancreaticojejunostomy o pancreaticogastrostomy en el tocón distal2,3. Estos dos enfoques son ampliamente utilizados en el pancreatectomies central abierta, laparoscópica y robótica4,5,6,7. Sin embargo, los enfoques de dos reconstrucción mencionadas rompen la continuidad anatómica del tracto digestivo y la vía para la excreción de líquido pancreático. El contacto directamente del muñón pancreático con jugo intestinal puede aumentar la posibilidad de hemorragia y la fístula8. Aunque el jugo gástrico podría inactivadas enzimas pancreáticas para evitar la erosión de la anastomosis, puede conducir a insuficiencia pancreática exocrina y en el largo plazo ponen en peligro estado nutricional9,10 del paciente.
Con el desarrollo de la cirugía mínimamente invasiva, cirugía robótica ha demostrado grandes ventajas en su vista 3-d aumento, estabilidad y flexibilidad de movimientos, etc., que proporciona mayor disección y sutura capacidad para anastomosis y hemostasia de11,12. Basándonos en nuestra experiencia en robótica pancreatectomy y reparación de conducto pancreático lesionado13,14, hemos realizado una serie de robótica Pancreatectomía central con anastomosis de punta a punta y visto resultados favorables. En comparación con pancreaticojejunostomy o pancreaticogastrostomy, anastomosis de páncreas end-to-end evita el daño al tracto digestivo; reduciendo teóricamente la posibilidad de fístula pancreaticoenteric. Pero por otro lado, la anastomosis de páncreas end-to-end presenta mayores dificultades técnicas. Como una actualización de Pancreatectomía central convencional, los candidatos a convencional Pancreatectomía central también son elegibles para esta cirugía. Aquí, presentamos técnicas operativas para robótica Pancreatectomía central con anastomosis de punta a punta en un centro terciario hepatopancreatobiliary en este video presentación del caso.
Indicaciones:
Benigno (1) y baja malignos potenciales tumores localizados en el cuello pancreático y cuerpo proximal son adecuados para esta operación. (2) el defecto del conducto pancreático principal debe ser menos de 5 cm después de la Pancreatectomía central y el tamaño del tumor no es la preocupación principal para la reconstrucción.
Presentación del caso:
El paciente es un hombre de 31 años de edad. Una lesión en el cuello pancreático fue encontrada accidentalmente en un examen médico hace 2 años. Él experimentó la revisión regular y la lesión fue encontrada para ser asintomáticamente agrandado recientemente. Él no tenía ninguna historia de cirugía abdominal previa. En la examinación física, no existió ningún signo positivo. El páncreas MRI demostrado una lesión casi circular de aproximadamente 14mm en el cuello pancreático; Esto se presume como un tumor neuroendocrino. En T1 y de T2-weighted imaging, la lesión demostrada hipointensa hiperintensa señal, respectivamente. En proyección de imagen difusión-cargada, la lesión demostró señales del hyperintense. La lesión fue ligeramente mayor en la fase arterial y demostró un patrón de mejora progresiva en la fase de parénquima y la fase de retardo (figura 1). Hígado graso severo también fue diagnosticado por MRI. No hay dilatación o estenosis fue detectada en el conducto pancreático. Examen de sangre rutinario, IgG isoforma prueba, biomarcadores tumorales, electrocardiograma y radiografía de tórax eran normales. La prueba bioquímica mostró levemente elevada ALT (alanina aminotransferasa) en 147.3 U/L y AST (aspartato aminotransferasa) en 53.9U / L, que puede ser causada por el hígado graso.

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			<td height="42" style="height:42px;width:205px;">da Vinci Robotic Surgical System</td>
			<td style="width:296px;">Intuitive&#160;Surgical, USA</td>
			<td style="width:113px;">Si</td>
			<td style="width:159px;"></td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">EndoWrist Permanent Cautery Hook</td>
			<td>Intuitive&#160;Surgical, USA</td>
			<td style="width:113px;">420183</td>
			<td></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:205px;">Harmonic Ace Curved Shears</td>
			<td>Ethicon, USA</td>
			<td style="width:113px;">420275</td>
			<td></td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">EndoWrist Large needle Driver</td>
			<td>Intuitive&#160;Surgical, USA</td>
			<td style="width:113px;">420006</td>
			<td></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:205px;">EndoWrist Cadiere Forceps</td>
			<td>Intuitive&#160;Surgical, USA</td>
			<td style="width:113px;">420049</td>
			<td></td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">EndoWrist Black Diamond Micro Forceps</td>
			<td>Intuitive&#160;Surgical, USA</td>
			<td style="width:113px;">420033</td>
			<td></td>
		</tr>
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			<td height="42" style="height:42px;width:205px;">Lapro-Clip 8 mm Absorbable Clips</td>
			<td>Covidien&#160; , USA</td>
			<td style="width:113px;">8886848882</td>
			<td></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:205px;">5-0 non-absorbable suture</td>
			<td>Ethicon, USA</td>
			<td style="width:113px;">M8717</td>
			<td></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:205px;">4-0 non-absorbable suture</td>
			<td>Ethicon, USA</td>
			<td style="width:113px;">D9775</td>
			<td></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:205px;">5-0 absorbable suture</td>
			<td>Ethicon, USA</td>
			<td style="width:113px;">D9943</td>
			<td></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:205px;">Absorbable hemostas</td>
			<td>Ethicon, USA</td>
			<td style="width:113px;">W1912</td>
			<td></td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Laparoscopic Ultrasound Probe</td>
			<td>BK Ultrasound, Denmark</td>
			<td style="width:113px;">8666-RF</td>
			<td>transducer contact surface: 30*5mm; Frequence: 4.3-10 MHz</td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:205px;">Pancreatic stent</td>
			<td>Yaxin Medical, Suzhou, China</td>
			<td style="width:113px;">1.2 mm&#160;</td>
			<td></td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Antibiotics&#160;(ceftriaxone sodium for injection)</td>
			<td style="width:296px;">Roche, Shanghai, China</td>
			<td style="width:113px;">H10983036</td>
			<td>ceftriaxone sodium (2g) adding to normal saline (100ml), once per day.</td>
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		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Proton pump inhibitors (lansoprazole injection)&#160;</td>
			<td style="width:296px;">Luoxin Pharmaceutical, Linyi, China</td>
			<td style="width:113px;">H20055118</td>
			<td>lansoprazole injection (30 mg) adding to normal saline (100ml), twice per day.</td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Somatostatin (Somatostatin for injection)</td>
			<td style="width:296px;">Merck Serono, Germany</td>
			<td style="width:113px;">H20090929</td>
			<td>Somatostatin for injection (6000ug) adding to nornal saline to a total of 48ml, 2 ml/h</td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:205px;">Analgesic</td>
			<td style="width:296px;"></td>
			<td style="width:113px;"></td>
			<td></td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Analgesic (sufentanil Citrate injection)</td>
			<td style="width:296px;">Humanwell Healthcare, Fuzhou, China</td>
			<td style="width:113px;">H20054171</td>
			<td>sufentanil Citrate (200ug),&#160; Ondansetron hyrochloride (20mg), adding to normal saline to a total of 80 ml, 1 ml/h</td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Analgesic (Ondansetron hyrochloride injection)</td>
			<td style="width:296px;">Qilu Pharmaceutical, Hainan, China</td>
			<td style="width:113px;">H10970065</td>
			<td>sufentanil Citrate (200ug),&#160; Ondansetron hyrochloride (20mg), adding to normal saline to a total of 80 ml, 2 ml/h</td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:205px;">Parenteral nutrition&#160;</td>
			<td style="width:296px;"></td>
			<td style="width:113px;"></td>
			<td></td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Parenteral nutrition(10% glucose injection)</td>
			<td style="width:296px;">Shijiazhuang No.4 Pharmaceutical&#65292;Shijiazhuang, China</td>
			<td style="width:113px;">H20133313</td>
			<td>1000 ml</td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Parenteral nutrition(5% glucose&#160; injection)</td>
			<td style="width:296px;">Shijiazhuang No.4 Pharmaceutical&#65292;Shijiazhuang, China</td>
			<td style="width:113px;">H13022474</td>
			<td style="width:159px;">250 ml</td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Parenteral nutrition(Compond vitamin injection)</td>
			<td style="width:296px;">Pude Pharmaceutical, Datong, China</td>
			<td style="width:113px;">H20093720</td>
			<td style="width:159px;">1 piece</td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Parenteral nutrition(Compond amino acid injection)</td>
			<td style="width:296px;">Kelun Pharmaceutical, Chengdu, China</td>
			<td style="width:113px;">H20066058</td>
			<td style="width:159px;">500 ml</td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Parenteral nutritionz(Fat emulsion injection)</td>
			<td style="width:296px;">Fresenius Kabi AB, Sweden</td>
			<td style="width:113px;">H20160019</td>
			<td style="width:159px;">250 ml</td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Parenteral nutrition(10%KCl injection)</td>
			<td style="width:296px;">Jinyao Pharmaceutical, Tianjin, China</td>
			<td style="width:113px;">H12020518</td>
			<td style="width:159px;">50 ml</td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Parenteral nutrition(10%NaCl injection)</td>
			<td style="width:296px;">CR, Double-Crane, Beijing, China</td>
			<td style="width:113px;">H11020865</td>
			<td style="width:159px;">50 ml</td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:205px;">Parenteral nutrition(Insulin injection)</td>
			<td style="width:296px;">No.1 biochemical and pharmaceutical, Shanghai, China</td>
			<td style="width:113px;">H31020519</td>
			<td style="width:159px;">28 Unit</td>
		</tr>
	</tbody>
</table>

application of end-to-end anastomosis in robotic central pancreatectomy

Pancreatectomía central se lleva a cabo para el tratamiento de tumores potenciales benignos o malignos bajo situado en el cuello pancreático o la parte proximal del cuerpo pancreático. Con desarrollo tecnológico, el sistema quirúrgico robótico ha demostrado sus ventajas en la cirugía mínimamente invasiva y cada vez más aplicado en Pancreatectomía central. Sin embargo, la reconstrucción de la continuidad del páncreas con end-to-end anastomosis después de la Pancreatectomía central robótico no se ha aplicado. En este estudio, divulgamos las técnicas quirúrgicas para robótica Pancreatectomía central con anastomosis de punta a punta. El páncreas es reconstruido por anastomosis del conducto a conducto del conducto pancreático con un stent pancreático en los dos muñones del conducto pancreático y por end-to-end anastomosis del parénquima pancreático. Comparado con el tradicional Pancreatectomía central con anastomosis pancreaticoenteric, este enfoque disminuye el daño quirúrgico al paciente y también conserva la integridad y la continuidad del conducto pancreático y tracto digestivo. El sistema quirúrgico robótico integrado con varios instrumentos con movimiento flexible y preciso es particularmente conveniente para la disección y la reconstrucción del conducto pancreático. Se encontró que la Pancreatectomía central robótico con end-to-end anastomosis es seguro y factible, y necesitamos más experiencia para evaluar sus mejores indicaciones y resultados a largo plazo.

El proceso de la operación era liso. El tiempo quirúrgico fue de 141 minutos y la pérdida de sangre intraoperatoria fue de aproximadamente 50 mL. El tamaño del páncreas resecado fue de 5,5 × 2,5 × 2,5 cm (figura 4). El paciente se recuperó sin problemas después de la cirugía y dados de alta enel día postoperatorio 6 . Cuando el paciente fue dado de alta, él tenía una dieta normal y la defecación normal y no tenía no fiebre, dolor abd...

Watch this Scientific Journal Video about Application of End-to-end Anastomosis in Robotic Central Pancreatectomy at JoVE.com

Application of End-to-end Anastomosis in Robotic Central Pancreatectomy

Aplicación de End-to-end Anastomosis en robótica Pancreatectomía Central

La Pancreatectomía central robótico con end-to-end anastomosis es factible y seguro para el tumor en el cuello pancreático y porción proximal del cuerpo pancreático. Se presentan las técnicas operativas de esta operación.

Central pancreatectomy is carried out for the treatment of benign or low-malignant potential tumors located in the pancreatic neck or proximal part of ...

This method can help answer key question about how to perform the robotic central pancreatectomy with an end-to-end anastomosis. The main advantages of this technique are that it simplifies the reconstruction approach after robotic central pancreatectomy, avoids pancreaticoenterostomy, and allows conservation of this anatomic continuity of the gastrointestinal tract. Demonstrating the procedure with me will be Gao Yuan-Xing and Xu Yong, associate senior doctors from my department.Before beginning the procedure, place the patient supine at a 20-degree reverse Trendelenburg position with the legs split, and drap the patient in the standard sterile fashion for upper abdominal surgery. Position the surgeon console in the operating room, the patient cart over the patient's head and vision cart to the right of the patient. Then direct the assistant surgeon to stand between the patient's legs with the back table for the instruments and supplies at the left rear of the assistant.When everything is in position, use a scalpel to make a one centimeter incision three centimeters inferior and right lateral to the umbilicus, and insert a veress needle through the incision into the abdominal cavity. Use the automatical insufflation instrument to establish a carbon dioxide pneumoperitoneum of 14 millimeters of mercury, and replace the veress needle with a 12 millimeter trocar as the camera port. Insert the robotic endoscope into the trocar, and perform a diagnostic laparascopy to confirm the abdominal adhesion status and operative feasibility.Under the view of the endoscope, place an 8 millimeter trocar in the left anterior axillary line at the level of the umbilicus for the first robotic arm, and place a 12 millimeter trocar 2 centimeter inferior and left lateral to the umbilicus as the assistant port. Place a 12 millimeter trocar in the right mid-clavicular line at the level of the umbilicus, and insert an 8 millimeter trocar into the right mid-clavicular 12 millimeter trocar in a trocar in trocar fashion for the second robotic arm. Then, place an 8 millimeter trocar under the costal margin in the right middle axillary line for the third robotic arm.Dock the robotic arm, and dock the robotic endoscope in the camera arm. To mobilize the pancreas neck and body, use the forceps on the third robotic arm to grasp and elevate the anterior wall of the the stomach to expose the gastrocolic ligament. Have the assistant apply tension in the gastrocolic ligament using the grasping forceps coupled with the bipolar forceps and the second robotic arm.Divide the gastrocolic ligament to enter the lesser sac, and use the laparoscopic ultrasonic scalpel on the first robotic arm to expose the anterior surface of the pancreas. Then, use the bipolar forceps on the second robotic arm to perform hemostasis until the level of the right gastroepiploic vein is reached. Using the cautery hook, carefully dissect the pancreatic neck from the inferior to superior direction, dividing the posterior wall of the pancreatic neck from the portal superior mesenteric, inferior mesenteric, and splenic veins.When the tissues have been divided, create a tunnel between the veins and the posterior wall of the pancreatic neck. Then use the cautery hook and ultrasonic scalpel to dissect the pancreatic body from the splenic vessels and connective tissues toward the pancreatic tail. To transect the pancreatic parenchyma, insert the laparoscopic ultrasound probe through the assistant trocar and perform ultrasonography on the pancreas to reconfirm the location and size of the lesion.According to the results of the ultrasonography, use the cautery hook to mark two transection lines on the pancreatic surface about one centimeter away from the lesion. Insert the fenestrated bipolar forceps through the inferior margin of the pancreas to lift the pancreatic body and further detach the proximal part of pancreatic body from the splenic vessels and connective tissues. Then mobilize the pancreatic neck and proximal pancreatic body from the posterior vessels and tissues.Using the ultrasonic scalpel, incise the pancreas parenchyma along the distal and proximal transection line and expose the pancreatic duct. Transect the pancreatic parenchyma around the pancreatic duct, and carefully protect and mobilize the pancreatic duct from the transected pancreatic parenchyma. Then use laparoscopic scissors from the assistant port to sharply transect the pancreatic duct about one centimeter away from the stump.To reduce the tension of the anastomosis, use the cautery hook and bipolor forceps to further mobilize the pancreatic stump from the posterior vessels and connective tissues. Implant the stent into the abdominal cavity through the assistant port and use microforceps to hold the sidewall of pancreatic duct stump within the pancreatic body. Gently insert the stent into the distal pancreatic duct stump, and use 5-0 absorbable sutures to suture the pancreatic duct with the stent so that the stent is closely encircled by the duct.Using a similar approach without a suture, insert the other end of the stent into the proximal pancreatic duct stump, followed by placement of a 4-0 nonabsorbable horizontal mattress suture around the proximal and distal pancreatic stumps. While pulling the two pancreatic stumps closer, continue to insert the proximal end of the stent into the proximal pancreatic duct stump. Next, perform an end-to-end anastomis of the pancreatic duct stumps using a 5-0 nonabsorbable suture with an interrupted stitch, and knot the remaining ties on the pancreatic stumps.Then use a 4-0 nonabsorbable suture to make a continuous stitch to suture the anterior portion of the pancreatic stumps. When the stumps have been secured, carefully check for bleeding, and conduct a thorough hemostasis, encircling the anastomosis site with absorbable hemostatic gauze as necessary. Place the resected specimen into a plastic sample bag, and remove the bag through the enlarged incision of the camera port.Place two drains along the superior and inferior borders of the anastomosis site, and extract the drains from the port for the third robotic arm. Then give the patient intravenous antibiotics, parenteral nutrition, analgesia, somatostatin, proton pump inhibitors, and other appropriate treatment according to conventional central pancreatectomy protocols. In this representative procedure, the resected pancreas was about 5.5 by 2.5 by 2.5 centimeters.After a smooth discharge and recovery, the postoperative CT scan revealed a slight exudation around the pancreas with no dilation or stricture in the pancreatic duct. While attempting this procedure, it is important to remember to transect the pancreatic duct sharply, and to fully mobilize the pancreatic stumps, particularly the distal pancreatic stump, prior to the end-to-end anastomosis to achieve the tension-free"anastomosis. After its development, this technique paved the way for researchers in the field of minimally invasive HPB surgery to explore the optimization of the reconstruction approaches for pancreatic duct and parenchyma after pancreatectomy.After watching the video, you should have to good understanding of how to use a robotic surgical system to perform the central pancreatectomy and to reconstruct the anatomic continuity of the pancreas by end-to-end anastomosis.

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