Dextran Sulfate Sodium (DSS) Colitis Induction and Evaluation
2:49
Histological Assessement
4:48
Immunohistochemistry and Gene Expression Assessment
7:19
Results: Representative Effects of Taste Signaling Protein Ablation on Gut Inflammation in DSS-induced Mice
8:23
Conclusion
Transcript
This method can help answer key questions in the inflammatory biodisease field about ulcerative colitis and Crohn's disease. The main advantage of this technique is that it can be used to evaluate first anti and proinfammatory effects of signaling
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Here we present a protocol to investigate the effect of the nullification of gustation-related genes on immune responses in a dextran sulfate sodium (DSS)-induced inflammatory bowel disease (IBD) mouse model.