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DOI :
10.3791/58672-v
•
10:44 min
August 9th, 2019
Chapters
0:04
Title
0:57
Preparation of OP9/DLL1 Cells for Co-culture with iPSC
2:08
In Vitro Differentiation of iPSC into Immature T Cells
5:00
3D Thymic Organ Culture to Generate iTE
8:00
Results: Generation of Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants
9:46
Conclusion
本文介绍了一种通过三维(3D)胸腺培养系统生成肿瘤抗原特异性诱导多能干细胞衍生胸腺(iTE)的新方法。iTE 是 T 细胞的同质子集,与天真的 T 细胞密切相关,具有增殖、记忆形成和肿瘤抑制的能力。
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