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DOI :
10.3791/58672-v
•
10:44 min
August 9th, 2019
Chapters
0:04
Title
0:57
Preparation of OP9/DLL1 Cells for Co-culture with iPSC
2:08
In Vitro Differentiation of iPSC into Immature T Cells
5:00
3D Thymic Organ Culture to Generate iTE
8:00
Results: Generation of Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants
9:46
Conclusion
本論文では、三次元(3D)胸腺培養系により腫瘍抗原特異的誘導多能性幹細胞由来の甲状腺系(iTE)を生成する新しい方法について説明する。iTEは、増殖、記憶形成、腫瘍抑制の能力を有するナイーブT細胞と密接に関連するT細胞の均質なサブセットである。
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