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DOI :
10.3791/59220-v
April 9th, 2019
Chapters
0:04
Title
0:36
Human Cerebral Microvascular Endothelial Cell (hCMEC)/D3 Insert Coating and Blood Brain Barrier (BBB) Preparation
2:48
BBB-Minibrain Endothelial Permeability Validation
3:38
BBB Crossing and Multiplication of Yellow Fever Viruses in the Minibrain and Biomolecule BBB Crossing and Brain Cell Targeting
5:22
Results: Representative BBB-Minibrain Testing of Neuroinvasive Variants and Biomolecule Properties
7:19
Conclusion
在这里, 我们提出了一个协议, 描述了设置在纤维素 BBB (血脑屏障)-minibrain 聚酯多孔膜培养插入系统, 以评估生物分子或传染因子在人类 BBB 的运输和对邻近脑细胞的生理影响。
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