Name: an ivor lewis esophagectomy designed to minimize anastomotic complications and optimize conduit function
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This study was approved by Indiana University-Purdue University in Indianapolis institutional review board (1109006832). This procedure was performed on all patients requiring resection and resection of the distal intrathoracic esophagus for malignant or benign diseases since 2009 at Indiana University Hospital.
1. Pre-anesthesia phase
<ol>
	<li>Place an epidural catheter.</li>
	<li>Obtain standard central venous and radial arterial access.</li>
	<li>Anesthetize and intubate using a double lumen left-sided endobronchial tube for selective lung ventilation during the thoracic phase of the operation.</li>
</ol>
2. Initial laparotomy phase
<ol>
	<li>Perform an upper midline laparotomy including excision of the zyphoid process with electrocautery. Place a self-retaining abdominal wall retractor for peritoneal cavity exposure.</li>
	<li>Perform a wide Kocher maneuver, which mobilizes the entire duodenum from the retroperitoneum. This maneuver not only straightens the gastric conduit, but also allows well-vascularized portions of the stomach conduit to be advanced above the azygos arch.</li>
	<li>Temporarily place a standard size laparotomy sponge under the duodenum to elevate the conduit, which is removed in the final laparotomy phase.</li>
	<li>Divide the gastrocolic ligament by cauterizing and dividing the omental blood vessels with a standard energy device. Avoid manipulation of the right gastroepiploic vessels by placing a nasogastric tube along the greater curvature, which is used as a &#8220;handle&#8221; retracting the stomach upward.</li>
	<li>Score the peritoneum circumferentially around the diaphragmatic crus with electrocautery and temporarily place a Penrose drain around the intraabdominal esophagus.</li>
	<li>Ligate the left gastroepiploic and short gastric vessels with a combination of suture and surgical clips. Then divide.</li>
	<li>In cases of malignancy, mobilize the celiac lymph bearing tissues from the superior aspect of the pancreas, which includes ligation and division of both left gastric artery and vein.</li>
	<li>Clear the lesser gastric curve of fat and blood vessels typically 3 to 5 cm distal to the gastroesophageal junction with vascular endostaplers. In cases of malignancy, plan the operations to achieve tumor free 3 to 5 cm distal stomach and 5 to 7 cm proximal esophageal surgical margins. As tumor locations range from the mid-esophagus to the gastric cardia, achieving adequate distal stomach and proximal esophageal margins results in conduits of varying lengths and associated lower or higher intrathoracic esophagogastric anastomoses. The specific site of the lesser curve clearing is therefore somewhat variable and dependent on exact tumor location.</li>
	<li>Cleave the upper gastric fundus and cardia from the remainder of the stomach typically using anywhere from 3 to 5 60 mm endoscopic staplers beginning from the greater gastric curve into the cleared area on the lesser gastric curve.</li>
	<li>Gastric conduit creation
	<ol>
		<li>Debulk lesser omental fat around the right gastric vessels, which allows the conduit to be straightened as well as lengthened. Division of right gastric vessels as they insert onto the lesser curve at the incisura will provide further lengthening.</li>
		<li>Secure the stomach at three points and provide outward retraction (Figure 1).</li>
		<li>Create a narrow uniform diameter conduit (average 7-8 cm) with an initial fire of the 100 mm stapler, which delivers two rows of 4.8 mm staples aiming just beneath the previous staple line. Completion of the conduit construction usually requires 2 or 3 additional fires of the 60 mm endoscopic tri-stapler into the cleared area on the lesser gastric curve. In cases of malignancy, send the stomach defect as the &#8220;distal stomach margin&#8221; for frozen section pathologic analysis.</li>
		<li>Inspect the tip of the conduit. Within 3 to 5 min, punctate bright red bleeding is usually seen through the lesser curve staple line representing good conduit perfusion. If no punctate bright red oozing is present, slightly trim the conduit tip with another 100 mm stapler until punctate bleeding is seen. Tri-staplers are not used for conduit trimming as cutting through and restapling the conduit tip during the intrathoracic anastomosis may be difficult.</li>
		<li>Perform a standard Heineke-Mikulicz pyloroplasty in order to assure good conduit emptying.</li>
		<li>Initially estimate how high in the chest the conduit will reach by comfortably stretching the conduit towards the neck without undue tension.</li>
		<li>Open the right pleura through the diaphragmatic crus. Place the conduit tip into the right chest keeping the lesser curve staple line facing rightward.</li>
		<li>Temporarily close the abdomen with a few interrupted fascial sutures and skin staples.</li>
	</ol>
	</li>
</ol>
3. Thoracic phase
<ol>
	<li>Place the patient in the left lateral decubitus position.</li>
	<li>Perform a serratus muscle sparing right thoracotomy through the 5th intercostal space. Divide the intercostal muscle underneath the incision within 3 to 5 cm of the vertebral body posteriorly and the sternum anteriorly, allowing additional movement of the 5th and 6th ribs with minimal risk of fracture or bruising.</li>
	<li>Excise the arch of the azygos vein and divide the inferior pulmonary ligament. In cases of malignancy, perform en bloc dissection by mobilizing the distal two-thirds of the intrathoracic esophagus with all surrounding soft tissues from the pericardium anteriorly to the aorta posteriorly esophageal blood vessels. Carefully occlude lymphatics with surgical clips before division during this dissection.</li>
	<li>Deliver the conduit into the right chest until there is no redundancy, limiting tension on the right gastric and right gastroepiploic vascular pedicles to determine the superior extent of esophageal dissection needed.</li>
	<li>At the level of the tracheal carina, dissect the esophageal wall from surrounding mediastinal soft tissues superiorly to a level where the tip of the conduit reaches without tension, which is usually 3 to 5 cm superior to the carina. Again however, given varying locations of tumors and length of stomach conduits created during the abdominal phase, establish anastomoses lower near the carina for gastric cardia tumors and higher at the thoracic inlet for tumors involving the middle intrathoracic esophagus.</li>
	<li>Creation of the esophagogastric anastomosis
	<ol>
		<li>Align the mid left lateral aspect of the upper third of the intrathoracic esophagus over the lesser curve staple line.</li>
		<li>Place four tacking sutures approximately 2 to 3 cm apart in order to maintain alignment (Figure 2).</li>
		<li>Transect the esophagus 1 cm distal to the inferior set of tacking sutures. In cases of malignancy, send a ring of esophagus at this level as the &#8220;proximal esophageal margin&#8221; for frozen section pathologic examination prior to proceeding.</li>
		<li>Create a corresponding 1 to 2 cm opening in the conduit across the lesser curve staple line.</li>
		<li>Place interrupted sutures within the common lumen, incorporating the adjacent conduit and esophageal walls beginning in the middle through the lesser curve staple line and progressing to either side (Figure 3).</li>
		<li>Place the narrow anvil of a 45 mm endoscopic stapler with a 4.1 mm staple height in the esophageal lumen and the large anvil in the conduit. To optimize the length of the side-to-side communication between the esophagus and the conduit, trim 5 mm from distal plastic tip of stapler cartridge with an oscillating saw.</li>
		<li>Fire the stapler, which cuts through and restaples the lesser curve staple line (Figure 4). The length of the cut end of the esophagus is usually somewhat longer than the edge of the gastric conduit, so remove an ellipse of the conduit over the lesser curve staple line rather than extending the rent laterally, preserving collateral blood supply (Figure 4 inset).</li>
		<li>Close the open common lumen in two layers of sutures beginning with an inner layer of inverted interrupted 3-0 polyglactin suture followed by a second layer of interrupted 3-0 silk using a Lembert technique (Figure 5).</li>
		<li>Over sew the upper aspect of the lesser curve conduit staple line with interrupted 3-0 silk sutures in a Lembert fashion extending inferiorly, until the right gastric vessels are encountered.</li>
		<li>Have the anesthesiologist place a nasogastric tube into the conduit to the level of the crus by palpation.</li>
		<li>For anastomoses created near the thoracic inlet, use a pleural flap to seal the anastomosis in the posterior mediastinum. For anastomoses in the middle aspect of the posterior mediastinum, mobilize a pericardial fat pat from anterior mediastinum and loosely wrapped to cover esophagogastric anastomosis (Figure 6 and Figure 7).</li>
		<li>Insert and position two 28-French chest tubes within the right hemithorax, one anterior and the other posterior, next to, but not abutting the conduit. Close the thoracotomy incision.</li>
	</ol>
	</li>
</ol>
4. Re-laparotomy: &#8220;double flip&#8221; phase
<ol>
	<li>Return patient to the supine position and reopen the midline laparotomy incision.</li>
	<li>Inspect the right gastroepiploic fat and carefully push any excess fat upwards through the left diaphragm crus into the chest.</li>
	<li>Secure the right gastroepiploic fat and conduit to the diaphragmatic crus with interrupted 2-0 silk sutures (Figure 8). Place a feeding jejunostomy tube in select patients, primarily in elderly patients or patients with preoperative nutritional deficits.</li>
	<li>Formally close the midline laparotomy incision.</li>
	<li>Keep patients intubated the evening of surgery with extubation planned the following morning.</li>
	<li>Provide pain control with epidural catheters placed just prior to anesthetic induction for the first 3 to 4 days, which is supplemented by intravenous narcotics.</li>
	<li>Obtain contrast upper gastrointestinal series 5 to 7 days postoperatively to assess for anastomotic integrity.</li>
	<li>If no anastomotic leak is identified, remove the nasogastric tube.</li>
	<li>Instruct patients to advance to a regular diet in 2 to 3 weeks after discharge as tolerated.</li>
</ol>

<ol>
	<li>Cassivi, S. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Leaks,+strictures,+and+necrosis:+a+review+of+anastomotic+complications+following+esophagectomy.">Leaks, strictures, and necrosis: a review of anastomotic complications following esophagectomy.</a> Seminars in Thoracic and Cardiovascular Surgery. 16, 124-132 (2004).</li><li>Low, D. E., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=International+consensus+on+standardization+of+data+collection+for+complications+associated+with+esophagectomy:+Esophagectomy+complication+consensus+group+(ECCG).">International consensus on standardization of data collection for complications associated with esophagectomy: Esophagectomy complication consensus group (ECCG).</a> Annals of Surgery. 262, 286-294 (2015).</li><li>Derogar, M., Orsini, N., Sadr-Azodi, O., Langergren, P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Influence+of+major+postoperative+complications+on+health-related+quality+of+life+among+long-term+survivors+of+esophageal+cancer+surgery.">Influence of major postoperative complications on health-related quality of life among long-term survivors of esophageal cancer surgery.</a> Journal of Clinical Oncology. 30, 1615-1619 (2012).</li><li>Kofoed, S. C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intrathoracic+anastomotic+leakage+after+gastroesophageal+cancer+resection+is+associated+with+increased+risk+of+recurrence.">Intrathoracic anastomotic leakage after gastroesophageal cancer resection is associated with increased risk of recurrence.</a> Journal of Thoracic and Cardiovascular Surgery. 150, 42-48 (2015).</li><li>Price, T. N., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+comprehensive+review+of+anastomotic+technique+in+432+Esophagectomies.">A comprehensive review of anastomotic technique in 432 Esophagectomies.</a> Annals of Thoracic Surgery. 95, 1154-1160 (2013).</li><li>Kassis, E. S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Predictors+of+anastomotic+leak+after+esophagectomy:+an+analysis+of+the+Society+of+Thoracic+Surgeons+General+Thoracic+Database.">Predictors of anastomotic leak after esophagectomy: an analysis of the Society of Thoracic Surgeons General Thoracic Database.</a> Annals of Thoracic Surgery. 96, 1919-1926 (2013).</li><li>Yuan, Y., Wang, K. N., Chen, L. Q. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Esophageal+anastomosis.">Esophageal anastomosis.</a> Diseases of the Esophagus. 28, 127-137 (2015).</li><li>Collard, J. M., Romagnoli, R., Goncette, L., Otte, J. B., Kestens, P. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Terminalized+semimechanical+side-to-side+suture+technique+for+cervical+esophagogastrostomy.">Terminalized semimechanical side-to-side suture technique for cervical esophagogastrostomy.</a> Annals of Thoracic Surgery. 65, 814-817 (1998).</li><li>Orringer, M. B., Marshall, B., Iannectoni, M. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Eliminated+the+cervical+esophagogastric+anastomotic+leak+with+a+side-to-side+stapled+anastomosis.">Eliminated the cervical esophagogastric anastomotic leak with a side-to-side stapled anastomosis.</a> Journal of Thoracic and Cardiovascular Surgery. 119, 277-288 (2000).</li><li>Wang, W. P., Gao, Q., Wang, K. N., Shi, H., Chen, L. Q. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+prospective+randomized+controlled+trial+of+semi-mechanical+versus+hand-sewn+or+circular+stapled+esophagogastrostomy+for+prevention+of+anastomotic+stricture.">A prospective randomized controlled trial of semi-mechanical versus hand-sewn or circular stapled esophagogastrostomy for prevention of anastomotic stricture.</a> World Journal of Surgery. 37, 1043-1050 (2013).</li><li>Kesler, K. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Outcomes+of+a+novel+intrathoracic+esophagogastric+anastomotic+technique.">Outcomes of a novel intrathoracic esophagogastric anastomotic technique.</a> The Journal of Thoracic and Cardiovascular Surgery. 156 (4), 1739-1745 (2018).</li></ol>

The authors have no disclosures.

Esophagectomy represents a very extensive surgical procedure. Adverse long-term quality of life has been linked to patients experiencing postoperative complications including anastomotic leaks3. Risk factors for an anastomotic leak primarily include creation of an anastomosis with poor blood supply. An anastomotic leak not only represents a significant source of postoperative morbidity, but also can commonly result in stricture. A stricture can also be a result of technical issues including performing a small diameter anastomosis. Besides impacting quality of life, strictures add to overall medical costs when dilatation is needed5. Accurately performing several steps is of utmost importance to minimize complications as well as achieve good oncologic and upper gastrointestinal tract functional outcomes.
Esophagogastric anastomosis can be accomplished by several methods, including hand sewn, EEA, and linear stapler techniques representing the majority. A report from the Society of Thoracic Surgeons General Thoracic Database cited an overall leak rate of 9.3% in patients undergoing intrathoracic esophagogastric anastomoses6. While postoperative mortality due to anastomotic leak seems to be decreasing, subsequent stricture rates remain high, ranging between 10 and 56%7. Collard and Orringer described a linear stapler technique to create a side-to-side cervical esophagogastric anastomosis8,9. The posterior triangulated opening formed by the linear stapler was demonstrated to result in a low leak rate as well as resistance to stricture. A retrospective study from Mayo Clinic reported a 5.6% incident of intrathoracic anastomotic leak in 177 patients where a linear stapled technique was used versus an 8.3% leak rate in 48 patients who underwent an EEA stapled anastomosis. While this difference did not reach statistical difference, the one-year probability for stricture was 32% after EEA anastomosis as compared to only 8.6% with linear stapled techniques, which was significant5. Wang and colleagues performed a prospective clinical trial involving 155 patients who were randomized into one of three esophagogastric anastomotic methods10. Impressively, no postoperative strictures developed in patients undergoing a linear stapler technique as compared to 9.6% and 19.1% in the hand sewn and circular stapled cases respectively, which was statistically significant. Prior studies involving linear stapler anastomoses have utilized the anterior wall of the stomach conduit for the anastomotic site. This approach may lead to an ischemic strip of conduit between the lesser curve staple line and the anastomosis predisposing to leak. Novel to our technique, collateral blood supply to the stomach conduit tip is preserved by cutting through and restapling the lesser curve staple line.
There are limitations to the study. First, this represents a retrospective analysis. Despite the retrospective nature however, we utilized this STS approach uniformly in all patients undergoing surgery for mid-esophageal to proximal stomach pathology over the study interval as an &#8220;intent to treat&#8221; including stable patients who sustained esophageal perforations during dilatation for stricture where repair was not possible. Common to any intrathoracic side-to-side anastomotic technique is the need to dissect an additional 3 to 4 cm of proximal esophagus, potentially decreasing the length of surgical esophageal margin in cases of malignancy and also potentially resulting in some degree of esophageal devascularization. To avoid devascularization, a critical point is not to dissect the intrathoracic esophagus any further superiorly toward the neck than the tip of the stomach conduit will reach without tension.We speculate the higher leak rate observed using this technique for patients with end-stage achalasia may be related to further devascularization of a thicken esophageal wall after mobilization to perform an STS anastomosis where the preexisting blood supply may be poor. Esophageal dilatation frequently seen in achalasia cases makes hand sewing the open common lumen very difficult, which may also be a factor.Based on this experience, we now believe that achalasia is a contraindication to perform STS intrathoracic anastomoses.Of note, for long or more central cancers where an esophagogastric anastomosis needs to be created near the thoracic inlet to achieve an adequate proximal esophageal margin, we have utilized a somewhat shorter initial side-to-side communication not utilizing the entire length of the 45 mm GIA which however has potential to be more prone to stricture formation.
Unlike the esophagus, the stomach is a passive conduit, gravity dependent for drainage. Several variables including conduit diameter and length as well as conduit orientation can, therefore, significantly impact upper gastrointestinal tract function. Ingested food has the potential to hang up in three locations: the esophagogastric anastomosis, the stomach body, and gastric outlet. Poor conduit function can be a result of technical issues in any of these three areas. Poor conduit emptying paradoxically can cause more &#8220;reflux,&#8221; not only negatively impacting quality of life but also occasionally resulting in aspiration. &#8220;Minimally invasive&#8221; (laparoscopic/thoracoscopic) approaches, which utilize an EEA stapler for esophagogastric anastomoses, although still representing the minority of esophagectomy cases performed, have become increasingly popular. We believe however our open technique as described not only allows creations of precise STS esophagogastric anastomosis to reduce the stricture rates but additionally optimizes conduit construction and orientation with a straight non-redundant stomach conduit including pyloroplasty with minimal tendency for ingested food materials to hang up in these areas as compared to thoracoscopic approaches. The measured contrast transit times from mouth to small bowel on routine postoperative studies would support excellent conduit function with our technique, however comparative studies using other techniques are needed. Our observations would support minimal and self-limiting &#8220;dumping&#8221; symptoms in the vast majority of STS patients however specific quality of life assessments are currently underway. Finally, with the thoracotomy approach described, we have observed little difference with respect to acute and long-term postoperative discomfort as compared to patients undergoing a thoracoscopic approach at our institution.
In summary, we believe this novel STS technique can significantly reduce the morbidity and occasional mortality of esophagogastric anastomotic complications following esophagectomy. Conduit construction and orientation as described additionally optimizes upper gastrointestinal tract function. Finally, this technique is easily adapted and reproducible.

Esophagogastric anastomotic leaks represent a not uncommon complication after esophagectomy1. Additionally, an anastomotic leak has been associated to unfavorable longer-term outcomes including hospital readmission, early mortality, and occasionally poor quality of life2,3,4. An anastomotic stricture represents a long-term complication, which can also be a consequence of an anastomotic leak5. Anastomotic strictures both negatively impact quality of life as well as escalate the cost of care.
As more esophageal cancer patients are living longer as a result of endoscopic detection of early stage adenocarcinoma and induction chemoradiation therapy for more locally advanced cancers, optimizing stomach conduit function also becomes important. Gastric conduit &#8220;function&#8221; mainly, however, relies on gravity for drainage. Gastric conduit construction and orientation can affect upper gastrointestinal tract function and therefore poor conduit &#34;function&#34;&#160;can be a result of technical issues.
We have used a novel &#34;side-to-side: staple line-on-staple line&#34;&#160;(STS) technique for intrathoracic esophagogastric anastomosis since 2009. This technique is designed to create a larger diameter anastomosis as compared to anastomoses made with end-to-end staplers (EEA) while simultaneously maintaining conduit blood supply to reduce the incidence of anastomotic leaks and strictures. We describe this novel anastomotic technique and additionally described gastric conduit construction and orientation to optimize function. We compared the results of this STS technique to anastomoses performed with EEA staplers over an 8-year time interval at our institution.

<table><tbody><tr><td>100 mm Linear Stapler (ILA Autosuture, &amp;ldquo;green&amp;rdquo; cartridge, 4.8 mm staple height)</td><td>Covidien</td><td>3973</td><td>Surgical Stapler</td></tr><tr><td>3-0 silk (Perma hand black, 8x18&quot;, SH needle, 1/2 circle 26 mm, C013)</td><td>Ethicon</td><td>C013D</td><td>Suture Material</td></tr><tr><td>3-0 silk (Perma hand black, 8x30&quot;, SH needle, 1/2 circle 26 mm, C017)</td><td>Ethicon</td><td>C017D</td><td>Suture Material</td></tr><tr><td>3-0 vicryl (Coated vicryl violet, 8x18&quot;, SH needle, 1/2 circle 26 mm, J774)</td><td>Ethicon</td><td>VCP774D</td><td>Suture Material</td></tr><tr><td>3-0 vicryl (Coated vicryl violet, 8x27&quot;, SH needle, 1/2 circle 26 mm, J784)</td><td>Ethicon</td><td>VCP784D</td><td>Suture Material</td></tr><tr><td>45 mm Endoscopic Stapler (Flex &amp;ldquo;green&amp;rdquo; cartridge, 4.1 mm staple height)</td><td>Ethicon</td><td>SC45A</td><td>Surgical Stapler</td></tr><tr><td>60 mm Endoscopic Tristapler</td><td>Ethicon</td><td>SC60A</td><td>Surgical Stapler</td></tr><tr><td>Flex &amp;ldquo;green&amp;rdquo; cartridge, 4.1 mm staple height</td><td>Ethicon</td><td>GST45G</td><td>Surgical Stapler</td></tr><tr><td>Flex 60, &amp;ldquo;black&amp;rdquo; cartridge (for 60 mm Endoscopic Tristapler)</td><td>Ethicon</td><td>GST60T</td><td>Surgical Stapler</td></tr><tr><td>Foceps Debakey 7.75 inch</td><td>Jarit</td><td>320-101</td><td>Surgical Instrument</td></tr><tr><td>Forceps Debakey 12 inch</td><td>Jarit</td><td>320-103</td><td>Surgical Instrument</td></tr><tr><td>Forceps Debakey 9.5 inch</td><td>Jarit</td><td>320-102</td><td>Surgical Instrument</td></tr><tr><td>Needle Holder Mayo-Hegar 10 inch</td><td>Codman</td><td>36-2019</td><td>Surgical Instrument</td></tr><tr><td>Needle Holder Mayo-Hegar 7 inch</td><td>Codman</td><td>36-2017</td><td>Surgical Instrument</td></tr><tr><td>Needle Holder Mayo-Hegar 8 inch</td><td>Codman</td><td>36-2018</td><td>Surgical Instrument</td></tr><tr><td>Needle Holder Ryder 10 inch</td><td>Codman</td><td>36-3005</td><td>Surgical Instrument</td></tr><tr><td>Needle Holder Ryder 9 inch</td><td>Jarit</td><td>121-164</td><td>Surgical Instrument</td></tr></tbody></table>

an ivor lewis esophagectomy designed to minimize anastomotic complications and optimize conduit function

We describe a novel esophagogastric anastomotic technique (&ldquo;side-to-side: staple line-on-staple line&rdquo;, STS) for intrathoracic anastomoses designed to create a large diameter anastomosis while simultaneously maintaining conduit blood supply. This technique aims to minimize the incidence of anastomotic leaks and strictures, which is a frequent source of morbidity and occasional mortality after esophagectomy. We analyze the results of this STS technique on 368 patients and compared outcomes to 112 patients who underwent esophagogastric anastomoses using an end-to-end stapler (EEA) over an 8-year time interval at our institution.
The STS technique involves aligning the remaining intrathoracic esophagus over the tip of the lesser curve staple line of a stomach tube, created as a replacement conduit for the esophagus. A linear stapling device cuts through and restaples the conduit staple line to the lateral wall of the esophagus in a side-to-side fashion. The open common lumen is then closed in two layers of sutures.
There was a total of 12 (3.8%) anastomotic leaks in patients who underwent STS esophagogastric anastomosis. Two of eight patients (25%) had anastomotic leaks after esophagectomy for end-stage achalasia as compared to a 2.8% leak rate (10/336) after esophagectomy for other conditions. Eighteen (5.2%) patients required a median of 2 dilatations for anastomotic stricture after STS anastomosis. Supplemental jejunostomy feedings were required in only 11.1% of patients undergoing STS anastomoses following hospital discharge. In contrast, patients undergoing EEA anastomoses demonstrated anastomotic leak and stricture rates of 16.1% and 14.3% respectively (p&lt;0.01). Time analysis of postoperative contrast studies following the STS technique typically demonstrated a straight/uniform diameter conduit with essentially complete contrast emptying into the small bowel within 3 minutes in 88.4% of patients.
The incidence of esophagogastric anastomotic leaks and strictures were extremely low using this novel anastomotic technique. Additionally we believe that based on time and qualitative analyses of postoperative contrast studies, this technique appears to optimize postoperative upper gastrointestinal tract function; however, further comparative studies are needed.

From 2009 to 2017, a total of 368 patients were identified who underwent an STS intrathoracic esophagogastric anastomosis and of these 12 (3.8%) had anastomotic leaks. Five of these patients demonstrated grade I/II leaks and required no intervention. Six patients and one patient respectively experienced grade III and grade IV leaks requiring endoscopic stenting and/or surgical intervention2. A leak rate of 25% (2/8) was observed after esophagectomy for end-stage achalasia as compared to a 2.8% leak rate (10/336) where esophagectomy was performed for other conditions. There were 4 (1.1%) patient who died postoperatively, none of which had an anastomotic complication. Of STS patients, 18 (5.0%) required a median of 2 dilatations for symptomatic anastomotic strictures. Supplemental jejunostomy feedings were required in only 11.1% of these patients following hospital discharge. In contrast, of the 112 patients identified who underwent thoracoscopic end-to-end mechanical stapler (EEA) anastomosis over this same time interval, 16.1% and 14.3% demonstrated anastomotic leaks and symptomatic strictures respectively (p&lt;0.01) despite all (100%) of these patients being maintained on a limited diet with supplemental jejunostomy tube feedings for at least one month following surgery (Table 1). Demographic and comorbidities of both STS and EEA groups were statistically similar; however, there was a trend towards more cardiac disease in the STS cohort (Table 2). Time analysis of postoperative contrast studies in first 208 patients who underwent an STS anastomosis typically demonstrated a straight/uniform diameter conduit with essentially complete (&gt;95%) contrast emptying into the small bowel within 3 min in 184 (88.4%) patients. The remaining 11.6% of patients studied, had near complete (&gt;95%) contrast emptying into the small bowel within 5 minutes. No patient studied had contrast transit time in excess of 5 minutes.
<img alt="Surgical technique, gastric bypass diagram, laparoscopic stapler, anatomical illustration." class="xfigimg" src="/files/ftp_upload/59255/59255fig01.jpg" data-altupdatedat="1747911167000" data-alt="Figure 1"> 
Figure 1: Creation of the stomach conduit. The stomach is secured at three points, which are retracted outward. A relatively uniform diameter conduit is created with staplers aiming just inferior to the previous staple line on the lesser curve. (Taken from with permission11.) <a href="https://www.jove.com/files/ftp_upload/59255/59255fig01large.jpg" target="_blank">Please click here to view a larger version of this figure.</a>
<img alt="Surgical incision diagram; depicts muscle layers and retraction for procedural clarity." class="xfigimg" src="/files/ftp_upload/59255/59255fig02.jpg" data-altupdatedat="1747911167000" data-alt="Figure 2"> 
Figure 2: Alignment of the esophagus over the stomach conduit. The mid left lateral aspect of the upper third of the intrathoracic esophagus is aligned over the lesser curve staple line at the tip of the conduit with 4 initial tacking sutures approximately 2 to 3 cm apart. (Taken from with permission11.) <a href="https://www.jove.com/files/ftp_upload/59255/59255fig02large.jpg" target="_blank">Please click here to view a larger version of this figure.</a>
<img alt="Surgical anastomosis diagram; vascular connection technique for blood flow restoration." class="xfigimg" src="/files/ftp_upload/59255/59255fig03.jpg" data-altupdatedat="1747911167000" data-alt="Figure 3"> 
Figure 3: Preparation for a side-to-side communication between the esophagus and stomach conduit. A 1 to 2 cm rent is made in the stomach conduit across the lesser curve staple line. Tacking sutures are placed between the adjacent conduit and esophageal walls beginning in the middle through the lesser curve staple line then two sutures on either side. (Taken from with permission11.) <a href="https://www.jove.com/files/ftp_upload/59255/59255fig03large.jpg" target="_blank">Please click here to view a larger version of this figure.</a>
<img alt="Surgical anastomosis diagram showing vessel connection with stapler method for tissue joining." class="xfigimg" src="/files/ftp_upload/59255/59255fig04.jpg" data-altupdatedat="1747911167000" data-alt="Figure 4"> 
Figure 4: Creation of a side-to-side communication between the esophagus and stomach conduit. A 45 mm endoscopic stapler is fired cutting through and restapling the lesser curve staple line. Typically only 2/3rds of the stapler length is used. An ellipse of conduit is removed over the lesser curve staple line (dotted line) rather than extending the rent laterally to equalize the length of the cut end of the esophagus and gastrotomy. (inset) (Taken from with permission11.) <a href="https://www.jove.com/files/ftp_upload/59255/59255fig04large.jpg" target="_blank">Please click here to view a larger version of this figure.</a>
<img alt="Surgical vascular anastomosis diagram with suturing technique and clamp placement." class="xfigimg" src="/files/ftp_upload/59255/59255fig05.jpg" data-altupdatedat="1747911167000" data-alt="Figure 5"> 
Figure 5: Closure of the open common lumen. The open common lumen is hand-closed in two layers of sutures beginning with inverted interrupted absorbable sutures. The first suture layer is imbricated by a second layer of Lembert silk sutures placing the stomach suture a few mm inferior to the first layer of sutures. (inset) (Taken from with permission11.) <a href="https://www.jove.com/files/ftp_upload/59255/59255fig05large.jpg" target="_blank">Please click here to view a larger version of this figure.</a>
<img alt="Breast surgical procedure diagram showing incision and sutures in anatomical context." class="xfigimg" src="/files/ftp_upload/59255/59255fig06.jpg" data-altupdatedat="1747911167000" data-alt="Figure 6"> 
Figure 6: Over sew of the lesser curve staple line and pleural buttress of the anastomosis. The superior aspect of the lesser curve conduit staple line can be over sewn at this point with interrupted silk sutures inferiorly until the right gastric vessels are encountered. For anastomoses established in near the thoracic inlet, a flap of mobilized pleura is tacked to the stomach conduit to contain small anastomotic leaks. (Taken from with permission11.) <a href="https://www.jove.com/files/ftp_upload/59255/59255fig06large.jpg" target="_blank">Please click here to view a larger version of this figure.</a>
<img alt="Surgical procedure diagram, hernia repair with mesh placement, anatomy and medical illustration." class="xfigimg" src="/files/ftp_upload/59255/59255fig07.jpg" data-altupdatedat="1747911167000" data-alt="Figure 7"> 
Figure 7: Vascularized soft tissue buttress of the anastomosis. Pericardial fat is loosely wrapped around anastomoses created in the middle aspect of the posterior mediastinum to contain any small areas of anastomotic dehiscence. <a href="https://www.jove.com/files/ftp_upload/59255/59255fig07large.jpg" target="_blank">Please click here to view a larger version of this figure.</a>
<img alt="Esophagectomy diagram showing reconstructed digestive pathway after esophagus removal surgery." class="xfigimg" src="/files/ftp_upload/59255/59255fig08.jpg" data-altupdatedat="1747911167000" data-alt="Figure 8"> 
Figure 8: Final (“double flip”) laparotomy phase. The laparotomy incision is reopened. The right gastroepiploic fat and conduit carefully tacked to the crus with 2-0 silk sutures. (Taken from with permission11.) <a href="https://www.jove.com/files/ftp_upload/59255/59255fig08large.jpg" target="_blank">Please click here to view a larger version of this figure.</a>
<table border="1" fo:keep-together.within-page="1" fo:keep-with-next.within-page="always">
	<tbody>
		<tr>
			<td></td>
			<td>STS (N=368)</td>
			<td>EEA (N=112)</td>
		</tr>
		<tr>
			<td>Anastomotic Leaks</td>
			<td>3.8%*</td>
			<td>16.1%</td>
		</tr>
		<tr>
			<td>Anastomotic Stricture</td>
			<td>5.2%*</td>
			<td>14.3%</td>
		</tr>
		<tr>
			<td>Post Op J-Tube Usage</td>
			<td>11.0%*</td>
			<td>100.0%</td>
		</tr>
	</tbody>
</table>
Table 1. Anastomotic leaks/strictures and use of postoperative feeding jejunostomy (Post Op J-Tube Usage) following hospital discharge comparing patients undergoing open STS and thoracoscopic EEA esophagogastric anastomoses using an Ivor Lewis approach performed at Indiana University Simon Cancer Center from 2009 to 2017. (*p value &lt; 0.01, chi-square)
<table border="1" fo:keep-together.within-page="1" fo:keep-with-next.within-page="always">
	<tbody>
		<tr>
			<td></td>
			<td>STS (n=278)</td>
			<td>EEA (n=82)</td>
			<td>P-Value</td>
		</tr>
		<tr>
			<td>Age at Diagnosis (yrs)</td>
			<td>60.3 ± 11.4 (23-84)</td>
			<td>60.6 ± 9.0 (38-80)</td>
			<td>0.80</td>
		</tr>
		<tr>
			<td colspan="4">Gender</td>
		</tr>
		<tr>
			<td>Male</td>
			<td>228 (82.0%)</td>
			<td>69 (84.1%)</td>
			<td>0.66</td>
		</tr>
		<tr>
			<td>Female</td>
			<td>50 (18.0%)</td>
			<td>13 (15.9%)</td>
			<td></td>
		</tr>
		<tr>
			<td colspan="4">Cormorbidity</td>
		</tr>
		<tr>
			<td>Cardiac</td>
			<td>114 (41.0%)</td>
			<td>24 (29.3%)</td>
			<td>0.06</td>
		</tr>
		<tr>
			<td>Diabetes Mellitus</td>
			<td>70 (25.2%)</td>
			<td>19 (23.2%)</td>
			<td>0.71</td>
		</tr>
		<tr>
			<td>COPD</td>
			<td>32 (11.5%)</td>
			<td>12 (14.6%</td>
			<td>0.45</td>
		</tr>
		<tr>
			<td colspan="4">Histology</td>
		</tr>
		<tr>
			<td>Adenocarcinoma</td>
			<td>237 (85.3%)</td>
			<td>74 (90.2%)</td>
			<td>0.25</td>
		</tr>
		<tr>
			<td>Other Diagnoses</td>
			<td>41 (14.7%)</td>
			<td>8 (9.8%)</td>
			<td></td>
		</tr>
		<tr>
			<td>Neoadjuvant Therapy</td>
			<td>200 (71.9%)</td>
			<td>59 (71.9%)</td>
			<td>0.99</td>
		</tr>
	</tbody>
</table>
Table 2: Demographic and comorbidity comparison open STS and thoracoscopic EEA anastomoses using an Ivor Lewis approach performed at Indiana University Simon Cancer Center from 2009 to 2015. Mean and standard deviation with range given for continuous variables. P values for continuous variables generated by Student’s t-test and chi-square for discrete variables.

Watch this Scientific Journal Video about An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function at JoVE.com

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function

We describe a novel intrathoracic esophagogastric anastomotic technique designed to create a large diameter anastomosis while simultaneously maintaining conduit blood supply to minimize the incidence of anastomotic leaks and strictures. Construction and orientation of the stomach conduit designed to optimize upper gastrointestinal tract function is also described.

We describe a novel esophagogastric anastomotic technique (&ldquo;side-to-side: staple line-on-staple line&rdquo;, STS) for intrathoracic anastomoses ...

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13.3K Views.  Indiana University Melvin and Bren Simon Cancer Center. We describe a novel intrathoracic esophagogastric anastomotic technique designed to create a large diameter anastomosis while simultaneously maintaining conduit blood supply to minimize the incidence of anastomotic leaks and strictures. Construction and orientation of the stomach conduit designed to optimize upper gastrointestinal tract function is also described.

Video: An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats

The use of biocompatible materials for circumferential esophageal reconstruction is a technically challenging task in rats and requires an optimal implant technique with nutritional support. Recently, there have been many attempts at esophageal tissue engineering, but the success rate has been limited due to difficulty in early epithelization in the special environment of peristalsis. Here, we developed an artificial esophagus that can improve the regeneration of the esophageal mucosa and muscle layers through a two-layered tubular scaffold, a mesenchymal stem cell-based bioreactor system, and a bypass feeding technique with modified gastrostomy. The scaffold is made of polyurethane (PU) nanofibers in a cylindrical shape with a three-dimensional (3D) printed polycaprolactone strand wrapped around the outer wall. Prior to transplantation, human-derived mesenchymal stem cells were seeded into the lumen of the scaffold, and bioreactor cultivation was performed to enhance cellular reactivity. We improved the graft survival rate by applying surgical anastomosis and covering the implanted prosthesis with a thyroid gland flap, followed by temporary nonoral gastrostomy feeding. These grafts were able to recapitulate the findings of initial epithelialization and muscle regeneration around the implanted sites, as demonstrated by histological analysis. In addition, increased elastin fibers and neovascularization were observed in the periphery of the graft. Therefore, this model presents a potential new technique for circumferential esophageal reconstruction.

Esophageal reconstruction is a challenging procedure, and development of a tissue-engineered esophagus that enables regeneration of esophageal mucosa and muscle and that can be implanted as an artificial graft is necessary. Here, we present our protocol to generate an artificial esophagus, including scaffold manufacturing, bioreactor cultivation, and various surgical techniques.

The use of biocompatible materials for circumferential esophageal reconstruction is a technically challenging task in rats and requires an optimal implant ...

Bioengineering

Laparoscopic Repair of Para-Esophageal Hernia Using Absorbable Biosynthetic Mesh

Para-esophageal hernia repairs are challenging procedures and there is no consensus on the optimal approach to repair. Mesh reinforcement has been associated with lesser hernia recurrence when compared to the primary suture repair. The type of mesh that is most appropriate is still debatable. Synthetic and biosynthetic materials have been studied in the literature. It is well documented that a synthetic mesh is associated with esophageal erosion and migration into the stomach. Though there are limited long-term data on biosynthetic mesh, the short-term results are excellent and promising.
This paper illustrates how a biosynthetic prosthesis can be safely used with fibrin glue fixation and anterior Dor fundoplication to repair any para-esophageal defect. The absorbable biosynthetic mesh has been shown to produce good long-term patient satisfaction outcomes and low recurrence rates compared to conventional methods including repair with synthetic mesh. This technique also avoids the risk of esophageal erosion whilst strengthening the repair. Tacks that are still widely used to secure the mesh can be abandoned due to the associated risk of developing cardiac tamponade, or other disastrous consequences. This repair method, also, highlights how the prosthesis can be fashioned into a V-shape and easily placed in an onlay fashion behind the esophagus. The protocol demonstrates an alternative and safer method for mesh fixation using fibrin glue.

Presented here is a protocol of para-esophageal hernia repair. Use of absorbable biosynthetic mesh avoids the risk of erosion through the esophagus whilst reinforcing the repair. Glue fixation is preferred to avoid the risk of trauma such as bleeding or cardiac tamponade, which are associated with stitches or tacks.

Para-esophageal hernia repairs are challenging procedures and there is no consensus on the optimal approach to repair. Mesh reinforcement has been ...

Medicine

Robotic Radical Cystectomy, Pelvic Lymph Node Dissection, and Intracorporeal Ileal Conduit Urinary Diversion

The robotic approach to radical cystectomy is compelling because of its oncologic equivalence to open radical cystectomy (ORC), its association with lower surgical blood loss, its potential association with shorter hospital stay after surgery. These factors suggest that the robotic approach to radical cystectomy may be an important component of enhanced recovery programs aimed at reducing surgical morbidity. This paper describes the importance of the cranial placement of robotic trocars, the use of Cadiere forceps for atraumatic bowel grasping, pelvic lymph node dissection (PLND), and utero-enteric anastomoses. Also discussed are steps that are critical for the successful outcome of RARC. In spite of the increased operating times and associated costs and the costs of robotic surgical platforms and equipment, adoption of the robotic technique by bladder cancer surgeons has increased. This paper describes a systematic and reproducible method that details robotic extended pelvic lymph node dissection, cystectomy/cystoprostatectomy, and intracorporeal ileal conduit urinary diversion.

This paper describes robotic radical cystectomy, pelvic lymph node dissection, and intracorporeal ileal conduit urinary diversion.

The robotic approach to radical cystectomy is compelling because of its oncologic equivalence to open radical cystectomy (ORC), its association with lower ...

Low-Cost Single-Port (LoCoSP) Device for a Transcervical Approach in Minimally Invasive Transhiatal Esophagectomy

Esophagectomy remains the preferred option to achieve curative treatment in advanced esophageal cancer, but the choice of surgical approach remains controversial. A transthoracic approach may improve lymph node dissection, but it has considerable morbidity and respiratory complications. Transhiatal access has been demonstrated as an efficient means of minimizing post-operative complications. Minimally invasive transhiatal esophagectomy may reduce operative trauma and morbidity as well as enhance postoperative recovery with no compromise in cancer recurrence or survival. Nevertheless, it has a technical limitation in terms of cervical esophagus dissection. Thus, a low-cost single-port device was developed to complete upper mediastinal dissection by a transcervical approach during minimally invasive transhiatal esophagectomy. This device uses a nasogastric tube, a number-eight sterile glove, a sterile sponge, and 3 permanent 5-mm trocars. The step-by-step process of transhiatal esophagectomy and the development of this device are described. This technique allows for the dissection of the upper mediastinum, as well as the esophagus over the aortic arch and behind the superior portion of the trachea. The harvesting of lymph nodes along the left recurrent laryngeal nerve and paratracheals was improved.

Low-Cost Single-Port LoCoSP Device for a Transcervical Approach in Minimally Invasive Transhiatal Esophagectomy

Here, we describe a step-by-step description of transhiatal esophagectomy and the development of a low-cost single-port device for a transcervical approach in a minimally invasive transhiatal esophagectomy.

Esophagectomy remains the preferred option to achieve curative treatment in advanced esophageal cancer, but the choice of surgical approach remains ...

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Reduced-port laparoscopic surgery (RPLS) has been widely used for the radical resection of gastrointestinal tumors. Single-surgeon, three-port, laparoscopic radical resection for sigmoid colon or high rectal cancer with natural orifice specimen extraction surgery (NOSES) has the advantage of a small incision, quick postoperative recovery, and short hospital stay. Yet, there are still only a few reports on NOSES. This paper describes the indications, preoperative preparations, surgical steps, and precautions for single-surgeon, three-port, laparoscopic radical resection of the sigmoid colon and high rectal cancer, and intraoperative specimen collection through the natural orifice. 
The protocol focuses on the steps of radical dissection and the main technical points of resection and reconstruction. At the same time, a procedure for fixing an anvil seat by self-traction of extracorporeal silk thread, used for purse-string suture fixation after the proximal anvil was placed in the abdominal cavity, was creatively improved. This operation could effectively avoid problems such as an insufficient proximal intestinal tube, shaking off the anvil seat, and weak purse-string suture during a single operation. The surgical care had less variability and was easy to perform, effectively avoiding postoperative anastomotic leakage and bleeding due to excessive intraoperative anastomotic tissue. This surgery could be widely promoted in primary hospitals.

Here, we present a protocol to successfully perform single-surgeon, three-port, laparoscopic resection for colorectal cancer with natural orifice specimen extraction.

Reduced-port laparoscopic surgery (RPLS) has been widely used for the radical resection of gastrointestinal tumors. Single-surgeon, three-port, ...

Robotic Myotomy and Partial Fundoplication for Achalasia

Laparoscopic Heller myotomy is currently considered the standard definitive treatment of achalasia. With the advancements in technology, robotic Heller myotomy has emerged as an alternative approach to traditional laparoscopy due to three-dimensional (3D) visualization, fine motor control, and improved ergonomics provided by the robot. 
Although there is a lack of randomized controlled trials, robotic-assisted Heller myotomy seems to be associated with lower rates of intraoperative perforations compared to the laparoscopic approach. A robotic approach may also improve surgical outcomes by providing a more complete myotomy. 
Here, we describe the detailed steps of robotic myotomy and partial fundoplication for achalasia.

Surgical myotomy with a partial fundoplication may be used in selected patients as a definitive treatment for achalasia. This article provides a step-by-step description of a robotic myotomy and partial fundoplication in a 32-year-old patient with megaesophagus.

Laparoscopic Heller myotomy is currently considered the standard definitive treatment of achalasia. With the advancements in technology, robotic Heller ...

Reoperative Hiatal Hernia Repair

Technical Considerations and Approach to Redo Foregut Surgery

Foregut surgical techniques have advanced significantly over the years and have become increasingly popular. However, new challenges and technical considerations have arisen when dealing with reoperation for complications or surgical failure. This study focuses on the technical considerations and approach when dealing with reoperative foregut surgery, particularly redo&#160;hiatal hernia repair. We describe our approach starting from the preoperative workup to the procedural steps of the surgery. The present study describes the main steps for robotic reoperative hiatal hernia repair in a patient who had previously undergone laparoscopic hiatal hernia repair with Nissen fundoplication but did not present a recurrence of reflux and dysphagia symptoms. The patient is positioned supine with arms out and a footboard for steep Trendelenburg. We place six trocars, including an assistant port and a liver retractor port,&#160;to facilitate visualization and retraction. After docking the robot, we use a combination of electrocautery and sharp dissection&#160;to free the hernia sac and reduce the hiatal hernia. The previous fundoplication is then taken down carefully and the esophagus is mobilized through a transhiatal approach with a combination of blunt and sharp dissection until at least 3 cm of intra-abdominal esophageal length is achieved, after which a leak test is performed. We then perform a crural repair to reapproximate the hiatus with two posterior stitches and one anterior stitch. Lastly, a redo Nissen fundoplication is performed over a bougie, and endoscopy is used to confirm a loose stack-of-coin appearance. By emphasizing the crucial steps of redo hiatal hernia repair, including preoperative evaluation, our goal is to provide an approach for the foregut surgeon to maximize patient outcomes.

Author Spotlight: Recent Advancements in Reoperative Foregut Surgery

Redo foregut surgery is associated with increased patient morbidity and presents a technical challenge for the surgeon. We describe our approach and considerations when performing a redo hiatal hernia repair to provide a guide for other surgeons and improve patient outcomes.

Foregut surgical techniques have advanced significantly over the years and have become increasingly popular. However, new challenges and technical ...

Treatment of Achalasia by Robot-Assisted Heller Myotomy

Robotic Heller Myotomy for Advancements in Surgical Management of Achalasia

Achalasia is an esophageal motility disorder. It occurs due to the destruction of nerves in the lower esophageal sphincter (LES), which leads to the failure of the LES to relax. Patients typically complain of dysphagia, chest pain, and regurgitation. They often report drinking liquids with solids intake to help propel food boluses into the stomach. The diagnosis of achalasia is typically confirmed with an esophagogram and a motility study (esophageal manometry). An esophagogram classically shows the bird beak sign with tapering in the distal esophagus. The treatment for achalasia includes both surgical and non-surgical options. Surgical treatment is associated with a lower rate of recurrences, high clinical success rate, and durability of symptom relief. The current gold standard of surgical technique is myotomy, or the dividing of the muscle fibers of the distal esophagus. Surgical myotomy can be accomplished via a laparoscopic or robotic technique; per-oral endoscopic myotomy is a new alternative intervention. Due to the theoretical risk of gastroesophageal reflux following a myotomy, an antireflux procedure is sometimes performed. We reviewed the approach to a robotic heller myotomy for the treatment of achalasia.

Author Spotlight: Cutting-Edge Robotic Heller Myotomy Protocol for Treatment of Achalasia

The protocol presents a robotic approach to Heller myotomy for the treatment of achalasia.

Achalasia is an esophageal motility disorder. It occurs due to the destruction of nerves in the lower esophageal sphincter (LES), which leads to the ...

Surgical Management of Persistent or New Symptoms After Hiatal Hernia Repair

Following a hiatal hernia repair, patients can present with recurrent or new symptoms. Symptoms can occur anywhere from weeks to years after surgery. These may include recurrent reflux, dysphagia, regurgitation, weight loss, or deteriorating quality of life. While nonoperative management can be pursued in some patients, reoperation may be the only option in select patients. A thorough preoperative workup, including a repeat esophagram, upper endoscopy, +/- chest computed tomography (CT) scan, manometry, pH probe, and/or gastric emptying study, is warranted to better understand the pathophysiology of the presenting symptoms. If a recurrent hernia, slipped, or migrated wrap is identified, surgery is considered. Pseudoachalasia must also be ruled out if obstructive symptoms are observed at the hiatus. Such an exhaustive workup is indeed necessary to ensure accurate diagnosis and optimal outcome. In addition, an understanding of the factors that may have led to the recurrence will increase the chances of a successful reoperation. Although a technically demanding procedure, redo hiatal hernia repair utilizing a minimally invasive approach is increasingly being employed with promising outcomes. Herein, the steps of a redo hiatal hernia repair via a minimally invasive approach will be outlined and detailed.

Redo foregut surgery is challenging in today's clinical practice and is fraught with increased morbidity and reportedly a lower 'success' rate than the index procedure. Here, we present a protocol for a redo hiatal hernia repair via a minimally invasive approach.

Following a hiatal hernia repair, patients can present with recurrent or new symptoms. Symptoms can occur anywhere from weeks to years after surgery. ...

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment

Single-incision plus one-port laparoscopic proximal gastrectomy with double-channel anastomosis (SILT-DT) is a minimally invasive surgical approach for treating proximal gastric cancer. This technique includes comprehensive laparoscopic resection of the proximal stomach, lymph node dissection, and double-tract anastomosis. By integrating single-port laparoscopic surgery with an auxiliary operating hole, SILT-DT reduces procedural difficulty while facilitating the placement of an abdominal drainage tube. Compared to the traditional five-port laparoscopic gastrectomy, SILT-DT requires fewer ports and results in shorter incision lengths, contributing to reduced postoperative pain and faster recovery. A thorough preoperative evaluation was conducted to ensure procedural success, with factors such as tumor size, stage, location, and patient BMI carefully considered. This comprehensive assessment allowed for optimal patient selection and surgical planning. Postoperative follow-up demonstrated no significant complications, underscoring the safety and efficacy of SILT-DT. This innovative technique offers a promising minimally invasive alternative for managing proximal gastric cancer while maintaining excellent clinical outcomes.

The single-incision plus one-port laparoscopic proximal gastrectomy with double-channel anastomosis was initially employed for the radical resection of proximal gastric cancer. This study demonstrated the feasibility of the procedure and laid a foundation for further research.

Single-incision plus one-port laparoscopic proximal gastrectomy with double-channel anastomosis (SILT-DT) is a minimally invasive surgical approach for ...

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function

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