Ocular Hypertension Induction by Intracameral Injection of Silicone Oil
2:33
Intracameral Silicon Oil Injection for One Eye
4:30
Silicone Oil Removal
5:59
IOP (Intraocular Pressure) Measurement Once a Week
7:02
Results: Quantification of Silicon Oil-Induced Ocular Hypertension and Degeneration in Mice
8:19
Conclusion
Transcript
Glaucoma is the leading cause of irreversible blindness, characterized by retinal ganglion cell death and the opto-neurodegeneration. Elevation of intraocular pressure, also called ocular hypertension, is the most recognized risk factor for glauco
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Here, we present a protocol to induce ocular hypertension and glaucomatous neurodegeneration in mouse eyes by intracameral injection of silicone oil and the procedure for silicone oil removal from the anterior chamber to return elevated intraocular pressure to normal.