En rotte halspulsåren Tryk-kontrolleret segmental ballon skade med Periadventitial Terapeutisk Application
July 9th, 2020
•1Department of Surgery, Division of Vascular Surgery, University of North Carolina at Chapel Hill, 2Center for Nanotechnology in Drug Delivery, University of North Carolina at Chapel Hill, 3Curriculum in Toxicology & Environmental Medicine, University of North Carolina at Chapel Hill, 4Department of Cell Biology & Physiology, University of North Carolina at Chapel Hill, 5McAllister Heart Institute, University of North Carolina at Chapel Hill
Den rotte halspulsåren ballon skade efterligner den kliniske angioplastik procedure, der udføres for at genoprette blodgennemstrømningen i aterosklerotiske fartøjer. Denne model fremkalder arteriel skade respons ved distending arteriel væg, og benægte intimal lag af endotelceller, i sidste ende forårsager remodeling og en intimal hyperplastisk reaktion.
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