Sign In

Enhanced Viability for Ex vivo 3D Hydrogel Cultures of Patient-Derived Xenografts in a Perfused Microfluidic Platform

5.9K Views

•

12:12 min

•

December 5th, 2020

DOI :

10.3791/60872-v

December 5th, 2020

•

5,905 Views

Lindsey K. Sablatura¹, Kristin M. Bircsak², Peter Shepherd³, Karla Queiroz⁴, Mary C. Farach-Carson^1,5,6, Pamela E. Constantinou^1,7, Anthony Saleh², Nora Navone³, Daniel A. Harrington^1,5,6

¹Department of BioSciences, Rice University, ²Mimetas US Inc, ³Department of Genitourinary Medical Oncology Research, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, ⁴Mimetas B.V., ⁵Department of Bioengineering, Rice University, ⁶Department of Diagnostic and Biomedical Sciences, The University of Texas Health Science Center, ⁷Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center

Chapters

Transcript

Summary

Explore More Videos

Keywords Patient derived Xenografts

3D Hydrogel Cultures

Microfluidic Platform

Ex Vivo Culture

Heterogeneous Systems

Tumor Architecture

Tumor Dissociation

Copyright © 2024 MyJoVE Corporation. All rights reserved