뮤린 정밀 절단 간 슬라이스 간 생물학의 Ex Vivo 모델로
March 14th, 2020
•Michael A. Pearen1*, Hong Kiat Lim1*, Francis D. Gratte2,3, Manuel A. Fernandez-Rojo1,4,5, Sujeevi K. Nawaratna6, Geoffrey N. Gobert7, John K. Olynyk8,9, Janina E. E. Tirnitz-Parker2,10, Grant A. Ramm1,4
1Hepatic Fibrosis Group, QIMR Berghofer Medical Research Institute, 2School of Pharmacy and Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University, 3School of Veterinary and Life Sciences, Murdoch University, 4School of Medicine, The University of Queensland, 5Madrid Institute for Advanced Studies (IMDEA) in Food, CEI UAM+CSIC, 6School of Medicine, Griffith University, 7School of Biological Sciences, Queen's University Belfast, 8Department of Gastroenterology & Hepatology, Fiona Stanley and Fremantle Hospital Group, 9School of Medical and Health Sciences, Edith Cowan University, 10Centre for Cell Therapy and Regenerative Medicine, School of Biomedical Sciences, University of Western Australia
이 프로토콜은 마우스에서 가능한 정밀 절단 간 조각의 생산을위한 간단하고 신뢰할 수있는 방법을 제공합니다. ex vivo 조직 샘플은 여러 날 동안 실험실 조직 배양 조건 하에서 유지될 수 있으며, 간 병리학을 검사하는 유연한 모델을 제공합니다.
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