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DOI :
10.3791/61139-v
June 23rd, 2020
Chapters
0:04
Introduction
0:34
Double-Carboxyl Polyethylene Glycol (CT-PEG) Synthesis
2:15
Poly(ethylenimine) Grafted with Polyethylene Glycol (PEI-g-PEG ) Copolymer Synthesis
4:03
PEI-g-PEG Coated Gold Nanoparticles (@AuNPs) Synthesis
5:05
DOX-g-PEI-g-PEG@AuNP Synthesis
6:11
AS1411-g-DOX-g-PEI-g-PEG@AuNP Synthesis
7:13
Results: Representative AuNP Characterization
8:33
Conclusion
このプロトコルでは、ドキソルビシンを装填したAS1411-g-PEI-g-PEG変性金ナノ粒子は、3段階のアミド反応を介して合成される。次いで、ドキソルビシンをロードし、癌治療のために標的癌細胞に送達する。
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