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DOI :
10.3791/61372-v
July 18th, 2020
Chapters
0:04
Introduction
0:34
Microbubble Quality Control
2:11
Fluorescent Antibody Labeling
2:46
Focused Scanning Ultrasound Setup (SUS)
4:29
Ultrasound Preparation
4:52
SUS Treatment
6:12
Results: Representative SUS Antibody Delivery Evaluation
6:48
Conclusion
여기에 제시된 프로토콜은 대소 또는 마우스 뇌 전체에 걸쳐 혈액-뇌 장벽 (BBB)을 일시적으로 열어 형광 표지 항체를 전달하고 미세 아교세포를 활성화시키는 프로토콜입니다. 또한 조직학에 의한 항체 전달 및 미세아교세포 활성화를 검출하는 방법이 제시된다.
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