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DOI :
10.3791/61469-v
July 25th, 2020
Chapters
0:04
Introduction
1:22
Fabrication of Dry Powder Insufflator and Loading of Dry Powder
2:36
Intubation
4:17
Powder Administration
5:25
Results: Optimization of Intratracheal Administration of mRNA Formulation
7:23
Conclusion
吸入用の乾燥粉末製剤は、呼吸器疾患の治療に大きな可能性を秘めています。ヒト研究に入る前に、前臨床試験における乾燥粉末製剤の有効性を評価する必要がある。気管内経路を介したマウスにおける乾燥粉末の投与の簡便かつ非侵襲的な方法が提示される。
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