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Single Myofiber Isolation og kultur fra en Murine Model af Emery-Dreifuss muskelsvind i tidlig postnatal udvikling

DOI :

10.3791/61516-v

8:07 min

July 1st, 2020

July 1st, 2020

7,043 Views

1Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi", 2IRCCS Santa Lucia Foundation, 3Department of Biology and Biotechnology, "C. Darwin" Sapienza University, CNR - IBPM, 4CNR – Institute of Biomedical Technologies (ITB)

Her foreslår vi en metode til effektivt at opnå enkelte muskelfibre i de tidlige postnatale udviklingsstadier fra homozygot mutant Lamin Δ8-11 musemodel, en meget alvorlig model for Emery-Dreifuss muskelsvind (EDMD).

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