Stretching Device Operation, Stretching and Imaging
5:42
Results: Representative Gel Strain Stretching and Gel Fiber Alignment Analysis
7:02
Conclusion
Transcript
Biological tissues grow in three-dimensional soft environments through which cells are exposed to various mechanical cues. Our method allows the stretching of hydrogels in a three-dimensional manner for the investigation of biomechanical responses
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Den presenterade metoden innebär enaxial sträckning av 3D mjuka hydrogeler inbäddade i silikongummi samtidigt som levande konfokal mikroskopi tillåts. Karakterisering av de yttre och inre hydrogelstammarna samt fiberjustering demonstreras. Enheten och protokollet som utvecklats kan bedöma cellernas reaktion på olika stamregimer.