Overvåking av Neutrophil Elastase og Cathepsin G Aktivitet i humane sputumprøver
May 21st, 2021
•1Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), 2Dept. of Translational Pulmonology, University of Heidelberg, 3Molecular Medicine Partnership Unit (MMPU), European Molecular Biology Laboratory (EMBL), University of Heidelberg, 4Faculty of Biosciences, Collaboration for Joint Ph.D. Degree between EMBL and Heidelberg University, University of Heidelberg, 5Dept. of Pediatric Pulmonology, Immunology and Critical Care Medicine, Charité – Universitätsmedizin Berlin, 6Berlin Institute of Health (BIH), 7German Center for Lung Research (DZL), Associated Partner Site, Berlin, 8Dept. of Chemical Physiology and Biochemistry, Oregon Health and Science University
Protokollene heri beskrevet gir en guide for å visualisere og kvantifisere aktiviteten til nøytrofile proteaser i menneskelig sputum. Anvendelsen av slik analyse spenner fra evaluering av antiinflammatoriske behandlinger, til biomarkørvalidering, legemiddelscreening og store kliniske kohortstudier.
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved