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DOI :
10.3791/62548-v
April 21st, 2021
Chapters
0:05
Introduction
0:45
Spherical Polymersome Formation Using a Solvent Injection Method
2:24
Dialysis to Remove Organic Solvent
3:05
Dialysis Against Salt Gradients and Shape Modulated Polymersome Characterization
3:50
Results: Modulating Shape of Polyester Based Polymersomes using Osmotic Pressure
5:36
Conclusion
ポリマーソームは、ギブの自由エネルギーを最小限に抑えるために球形で形成される自己組織化されたポリマー小胞である。薬物送達の場合、より細長い構造が有益である。このプロトコルは、塩を使用して浸透圧を誘導し、内部の小胞体積を減少させるために、細長いアスペクト比を持つ、より多くの棒状ポリマーソームを作成する方法を確立します。
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