Name: interview: glycolipid antigen presentation by cd1d and the therapeutic potential of nkt cell activation
Uploaded: 2007-12-31T19:27:00
Description: Watch this Scientific Journal Video about Interview: Glycolipid Antigen Presentation by CD1d and the Therapeutic Potential of NKT cell Activation at JoVE.com

<ol>
	<li>Khurana, A., Kronenberg, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+Method+for+Production+of+Recombinant+CD1d+Protein+in+Insect+Cells.">A Method for Production of Recombinant CD1d Protein in Insect Cells.</a> 12/10/2007) Journal of Visualized Experiments. , .</li></ol>

interview: glycolipid antigen presentation by cd1d and the therapeutic potential of nkt cell activation

自然杀伤T细胞（NKT细胞）的免疫反应的癌症，调节autioimmune疾病，传染性病原体的间隙，artheriosclerotic斑块的发展的关键因素。在这次采访中，米奇Kronenberg讨论他的实验室的努力去了解通过糖脂抗原激活NKT细胞的机制。这些研究的核心是CD1d - 呈现糖脂NKT细胞的抗原提呈分子。 CD1d四聚体技术的问世，由Kronenberg实验室开发出一种技术，具体糖脂反应性T细胞亚群的分类和识别的关键。米奇解释糖脂受体激动剂作为治疗药物激活NKT细胞在癌症患者中，以及如何CD1d四聚体可以用来评估在体内糖脂受体激动剂治疗后NKT细胞人口的状态。正在进行的临床试验，使用这些受体激动剂的现状进行了讨论，以及米奇的预测，在免疫学领域的地区，将出现在不久的将来的重要性。

Watch this Scientific Journal Video about Interview: Glycolipid Antigen Presentation by CD1d and the Therapeutic Potential of NKT cell Activation at JoVE.com

Interview: Glycolipid Antigen Presentation by CD1d and the Therapeutic Potential of NKT cell Activation

自然杀伤T细胞（NKT），癌症autioimmunity监管，清除感染，并发展artheriosclerotic斑块的免疫反应的关键因素。在这次采访中，米奇Kronenberg讨论他的实验室的努力去了解通过糖脂抗原激活NKT细胞的机制。

专访：糖脂抗原提呈CD1d及NKT细胞活化治疗潜力

Natural Killer T cells (NKT) are critical determinants of the immune response to cancer, regulation of autioimmune disease, clearance of infectious ...

Research

JoVE Journal

Biology

Christopher Hughes:  An in vitro model for the Study of Angiogenesis (Interview)

Christopher Hughes:  An in vitro model for the Study of Angiogenesis Interview

克里斯托弗休斯：在体外血管生成的研究模型（面试）

Christopher C.W. Hughes describes the utility of his culture system for studying angiogenesis in vitro.  He explains the importance of fibroblasts that ...

科研

生物学

Investigating the Microbial Community in the Termite Hindgut - Interview

调查白蚁后肠中的微生物的社区 - 面试

Jared Leadbetter explains why the termite-gut microbial community is an excellent system for studying the complex interactions between microbes.     The ...

Microbial Communities in Nature and Laboratory - Interview

微生物群落，在自然和实验室 - 面试

Studies of Bacterial Chemotaxis Using Microfluidics - Interview

使用微流体的细菌的趋化作用的研究 - 访

Biology of Microbial Communities  - Interview

微生物群落的生物 - 面试

Regulatory T cells: Therapeutic Potential for Treating Transplant Rejection and Type I Diabetes

调节性T细胞治疗移植排斥反应和I型糖尿病的治疗潜力

Interview: Protein Folding and Studies of Neurodegenerative Diseases

专访：蛋白质折叠与神经退行性疾病的研究

In this interview, Dr. Lindquist describes relationships between protein folding, prion diseases and neurodegenerative disorders. The problem of the ...

Interview: Bioreactors and Surfaced-Modified 3D-Scaffolds for Stem Cell Research

专访：干细胞研究的生物反应器和三维支架材料表面改性

A Nature Editorial in 2003 asked the question  "Good-bye, flat biology?"  What does this question imply? In the past, many in vitro culture systems,  ...

Interview: HIV-1 Proviral DNA Excision Using an Evolved Recombinase

专访：HIV - 1前病毒DNA切除使用一个演进的重组酶

HIV-1 integrates into the host chromosome of infected cells and persists as a provirus flanked by long terminal repeats. Current treatment strategies ...

Activation of Apoptosis by Cytoplasmic Microinjection of Cytochrome c

Activation of Apoptosis by Cytoplasmic Microinjection of Cytochrome c

激活细胞凋亡的细胞色素的细胞质显微注射 C</em

Apoptosis, or programmed cell death, is a conserved and highly regulated pathway by which cells die1.  Apoptosis can be triggered when cells encounter a ...