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DOI :
10.3791/63744-v
May 12th, 2023
Chapters
0:04
Introduction
0:56
Sample Processing
3:11
Establishment of Zebrafish‐Based Patient‐Derived Xenografts (zPDX)
4:56
Treatment and Imaging
5:40
Results: Establishment of Zebrafish‐Based Patient‐Derived Xenografts (zPDXs) from Primary Human Pancreatic Adenocarcinoma
6:14
Conclusion
前臨床モデルは、がん生物学の知識を進歩させ、治療効果を予測することを目的としています。この論文では、腫瘍組織断片を用いたゼブラフィッシュベースの患者由来異種移植片(zPDX)の生成について説明します。zPDXを化学療法で治療し、その治療効果を移植組織の細胞アポトーシスに関して評価した。
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