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DOI :
10.3791/64159-v
•
7:06 min
July 6th, 2022
Chapters
0:05
Introduction
1:08
Pre-Operative Care
2:21
Destabilization of the Medial Meniscus Procedure Followed by Cartilage Scratch
4:16
Post-Operative Care and Evaluation of Osteoarthritic Disease
5:29
Results: Destabilization of the Medial Meniscus and Cartilage Scratch Model to Study Post-Traumatic Osteoarthritis
6:24
Conclusion
本协议描述了通过切割内侧小肩韧带破坏小鼠膝盖稳定性后关节软骨表面上受控的微刀片划痕。该动物模型呈现了一种加速形式的骨关节炎(OA),适用于研究骨赘形成,骨硬化和早期疼痛。
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