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DOI :
10.3791/64216-v
August 2nd, 2022
Chapters
0:04
Introduction
1:06
Preparation of Cancer Cells for Injection
3:01
Preparation of the Mouse for the Procedure
4:06
Internal Carotid Injection and Post-Injection Recovery
7:44
Results: Generation of Brain Metastasis Murine Model for Screening and Evaluating the Therapeutic Profile of Drugs
9:23
Conclusion
脳転移は、癌患者の重度の罹患率と死亡率の原因です。ほとんどの脳転移マウスモデルは、死亡率および治療介入結果の交絡分析を混乱させる全身性転移によって複雑になります。ここに提示されるのは、最小限の全身腫瘍で一貫した頭蓋内腫瘍を生成する癌細胞の内部頸動脈注射のためのプロトコルです。
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