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间变性甲状腺癌的自发性鼠模型

DOI :

10.3791/64607-v

February 3rd, 2023

February 3rd, 2023

1,206 Views

1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, 2Division of Thyroid Surgery, Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-Related Molecular Network, Department of General Surgery, West China Hospital, Sichuan University, 3Department of Ultrasound, West China Hospital of Sichuan University, Sichuan University, 4Department of Otolaryngology-Head & Neck Surgery and University of Arizona Cancer Center, University of Arizona, 5Center for Translational Medicine, Shenzhen Bay Laboratory, 6Division of Laboratory Medicine/Research Centre of Clinical Laboratory Medicine, West China Hospital, Sichuan University

在这里,我们提出了一种通过自发基因工程小鼠模型获得鼠ATC肿瘤的标准管道。此外,我们呈现有关原发性和转移性病变的肿瘤动力学和病理信息。该模型将帮助研究人员了解肿瘤发生并促进药物发现。

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