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An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice

DOI :

10.3791/64863-v

March 3rd, 2023

March 3rd, 2023

1,382 Views

1Division of Systems Neuroscience, New York State Psychiatric Institute, 2Department of Psychiatry, Columbia University

Here, we present a simplified open-source hardware and software setup for investigating mouse spatial learning using virtual reality (VR). This system displays a virtual linear track to a head-restrained mouse running on a wheel by utilizing a network of microcontrollers and a single-board computer running an easy-to-use Python graphical software package.

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