This study has been approved by the Ethics Committee of the Third Hospital of Hebei Medical University. The patients signed informed consent, consented to be filmed, and allowed the investigators to use their surgical data.
1. Patient selection
<ol>
	<li>Select patients based on the following inclusion criteria.
	<ol>
		<li>Select patients for whom conservative treatment time was longer than 3 months and to which the patients responded poorly.</li>
		<li>Select patients whos...

Since formally introduced by Silvestre in 201223, OLIF has gradually attracted the attention of spine surgeons due to the various advantages over other methods used in treating lumbar spine diseases6,12,13,16,21,22. OLIF significantly improved patients' disc height and lordotic angle, which may be due ...

Lumbar spine disorders are a global economic concern, with affected patients experiencing lower quality of life1. The treatment of lumbar spine diseases can be divided into two categories: conservative and surgical treatment. Conservative treatment includes rest, oral nonsteroidal drugs, massage, and physical therapy. For instance, studies have shown that estrogen can be used to delay degeneration of the intervertebral disc, thus providing a basis for its treatment of lumbar spine disease2,3. For patients who have failed in conservative treatment, surgery is typically required to treat lumbar spine diseases. Among the surgical methods used for this cohort, interbody fusion is generally preferred.
Briefly, the techniques reported consist of anterior lumbar interbody fusion (ALIF), direct lateral interbody fusion (DLIF), extreme lateral interbody fusion (XLIF), oblique lateral interbody fusion (OLIF), posterior lumbar interbody fusion (PLIF), and transforaminal lumbar interbody fusion (TLIF)4,5. Among these surgical approaches, OLIF has its unique advantages. In comparison with DLIF and XLIF, OLIF has been shown to reduce the incidence of postoperative hip flexion weakness and thigh numbness6,7. Moreover, compared with ALIF, surgeries with OLIF have a lower risk of both postoperative retrograde ejaculation and damage of blood vessels anterior to the vertebral body8. Nonetheless, it is worth mentioning that PLIF and TLIF techniques exhibit a good operative field, which could reduce damage to important structures; the placement of pedicle screws used by these methods could reduce the probability of non-fusion of the interbody cage. Nonetheless, compared with OLIF, PLIF and TLIF require intraoperative muscle dissociation and stretching the muscle for an extended period of time, which could result in increased intraoperative blood loss, slow wound healing, and prolonged patient recovery time9,10,11.
By harnessing the OLIF approach, the intervertebral site can be accessed through the space between the anterior border of the psoas muscle and the major abdominal vessels. The surgery is performed by removing the diseased disc and implanting an interbody cage. Because of the reduced damage to muscle, OLIF can minimize intraoperative blood loss and operation time, shortening patients&#39; postoperative recovery. In addition, earlier studies have shown that the placement of interbody cages can boost restoration of the disc height and patients&#39; physiological curvature of the spine6,12,13,14,15,16. In the present study, the surgical procedures of stand-alone OLIF for the treatment of L4-5 lumbar diseases are introduced in detail.

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application of stand-alone oblique lateral interbody fusion in l4-5 lumbar diseases

Lumbar spine diseases often cause lower back pain, lower extremity pain, numbness, and paresthesia. In severe cases, intermittent claudication may occur, affecting the quality of life of patients. Surgery is often required when conservative treatment fails, or when patients' symptoms become unbearable. Surgical treatments include laminectomy and discectomy, as well as interbody fusion. The main purpose of laminectomy and discectomy is to relieve nerve compression; however, recurrence is common due to spinal instability. Interbody fusion improves stability while relieving nerve compression and significantly reduces the risk of recurrence compared to non-fusion surgery. Nonetheless, conventionally posterior intervertebral fusion requires separation of the muscles to expose the operated segment, which causes more trauma to the patient. In contrast, the oblique lateral interbody fusion (OLIF) technique achieves spinal fusion with minimal trauma to the patients and shortens the recovery time. This article introduces procedures of stand-alone OLIF surgery performed in the lumbar spine, providing a reference for other spine surgeons.

Studies from other groups have shown that, compared to other methods, OLIF surgery has the advantages of a shorter operative time and less intraoperative blood loss (Table 1). Importantly, patients who undergo OLIF surgery recover faster than the commonly used TLIF surgery group12,21,22. Our research group has monitored 42 patients with degenerative lumbar spondylolisthesis (DLS) undergoing OLIF surgery for more...

Read this Scientific Article Protocol about Application of Stand-Alone Oblique Lateral Interbody Fusion in L4-5 Lumbar Diseases at JoVE.com

Application of Stand-Alone Oblique Lateral Interbody Fusion in L4-5 Lumbar Diseases

This study describes the application of oblique lateral interbody fusion in lumbar spinal surgeries.

Lumbar spine diseases often cause lower back pain, lower extremity pain, numbness, and paresthesia. In severe cases, intermittent claudication may occur, ...