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Please note that all translations are automatically generated. Click here for the English version.
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01:22 min
February 9th, 2024
DOI :
10.3791/66520-v
Transcript
我们采用了一种新颖的策略,该策略涉及采用脱细胞的脾脏基质作为生物人工肝的替代支架。我们展示了收获大鼠脾脏和制备脱细胞脾基质的详细过程,该基质保留了细胞外基质的宏观结构和成分。我们的方案提供了一个现成的脾脏基质,作为稀缺供体肝脏的替代品。
我们的方案提出了一种制备脱细胞脾脏基质的方法。该方法具有效率、稳定性和微创性,可保持脾脏固有的结构、组成和自然血管网络。它为细胞植入和三维动态培养提供了支架,从而为推进组织工程肝脏的研究奠定了基础。
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