Questo studio è stato finanziato dall'Università Mae Fah Luang. Gli autori ringraziano il Tea and Coffee Institute dell'Università di Mae Fah Luang per aver facilitato il collegamento tra i ricercatori e gli agricoltori locali per quanto riguarda l'acquisizione di campioni di caffè silverskin.

I dettagli dei reagenti e delle attrezzature utilizzate in questo studio sono elencati nella tabella dei materiali.
1. Preparazione sperimentale
<ol><li>Preparazione del campione di piante<ol><li>Raccogliere il caffè fresco silverskin (Coffea arabica) e asciugarlo a 60 °C in un essiccatoio a vaschette per 72 h11.</li>
		<li>Macinare il caffè essiccato silverskin (CS) in una polvere fine utilizzando un macinino e conservarl...

Estrazione assistita da microonde a base di polioli per rese fenoliche e antiossidanti

<ol>
	<li>Wawoczny, A., Gillner, D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+most+potent+natural+pharmaceuticals,+cosmetics,+and+food+ingredients+isolated+from+plants+with+deep+eutectic+solvents.">The most potent natural pharmaceuticals, cosmetics, and food ingredients isolated from plants with deep eutectic solvents.</a> J Agric Food Chem. 71 (29), 10877-10900 (2023).</li><li>Syukur, M., Prahasiwi, M. S., Yuliani, S., Purwaningsih, Y., Indriyanti, E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Profiling+of+active+compounds+of+extract+ethanol,+n-hexane,+ethyl+acetate+and+fraction+ethanol+of+star+anise+(Illicium+verum+hook.+F.)+and+determination+of+total+flavonoids,+total+phenolics+and+their+potential+as+antioxidants.">Profiling of active compounds of extract ethanol, n-hexane, ethyl acetate and fraction ethanol of star anise (Illicium verum hook. F.) and determination of total flavonoids, total phenolics and their potential as antioxidants.</a> Sci Technol Indones. 8 (2), 219-226 (2023).</li><li>Supjaroenporn, C., Khongcharoen, P., Myo, H., Khat-Udomkiri, N. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Studying+the+optimization,+characterization,+and+antioxidant+activities+of+phenolic+extracts+extracted+from+Rhus+chinensis+Mill.+Leaf+using+microwave-assisted+extraction+system+with+glycerol+as+a+green+solvent.">Studying the optimization, characterization, and antioxidant activities of phenolic extracts extracted from Rhus chinensis Mill. Leaf using microwave-assisted extraction system with glycerol as a green solvent.</a> Curr Bioact Compd. 20 (3), 68-82 (2024).</li><li>Gasser, M. S., Abdel Rahman, R. 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A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Solvent+effect+on+the+competition+between+weak+and+strong+interactions+in+phenol+solutions+studied+by+near-infrared+spectroscopy+and+DFT+calculations.">Solvent effect on the competition between weak and strong interactions in phenol solutions studied by near-infrared spectroscopy and DFT calculations.</a> Phys Chem Chem Phys. 23 (35), 19188-19194 (2021).</li><li>Lu, W., Mackie, C. J., Xu, B., Head-Gordon, M., Ahmed, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+computational+and+experimental+view+of+hydrogen+bonding+in+glycerol+water+clusters.">A computational and experimental view of hydrogen bonding in glycerol water clusters.</a> J Phys Chem A. 126 (10), 1701-1710 (2022).</li><li>Fan, C., Liu, Y., Sebbah, T., Cao, X. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+theoretical+study+on+terpene-based+natural+deep+eutectic+solvent:+Relationship+between+viscosity+and+hydrogen-bonding+interactions.">A theoretical study on terpene-based natural deep eutectic solvent: Relationship between viscosity and hydrogen-bonding interactions.</a> Glob Chall. 5 (3), 2000103 (2021).</li><li>Liese, S., Schlaich, A., Netz, R. 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Vari fattori giocano un ruolo cruciale nell'implementazione di successo del MAE, come il contenuto fitochimico dei componenti della pianta, la durata dell'estrazione, la temperatura, la potenza delle microonde, il rapporto solido-liquido e la concentrazione del solvente13. Le piante mostrano tipicamente profili variabili di sostanze fitochimiche; Pertanto, la selezione di piante naturali ricche di antiossidanti e composti fenolici è essenziale23. Inoltre, i diversi costitu...

Al giorno d'oggi, c'è una tendenza globale verso la consapevolezza ambientale nell'industria della bellezza, che porta i produttori a concentrarsi sulla tecnologia verde per l'estrazione di componenti vegetali utilizzando alternative sostenibili1. In genere, i solventi tradizionali come l'etanolo, il metanolo e l'esano vengono utilizzati per estrarre componenti fenolici vegetali e antiossidanti naturali2. Tuttavia, la presenza di residui di solventi all'interno degli estratti vegetali rappresenta un potenziale rischio per la salute umana, inducendo irritazione della pelle e degli occhi3, in particolare per quanto riguarda la loro applicazione prevista nei cosmetici. Di conseguenza, è difficile eliminare tali residui di solvente dagli estratti, un processo che richiede un notevole investimento in tempo, energia e risorse umane4. Recentemente, l'acqua surriscaldata, i liquidi ionici, i solventi eutettici profondi e i solventi bioderivati sono emersi come approcci promettenti per l'estrazione con solventi ecologici5. Tuttavia, il loro utilizzo è ancora limitato dalla separazione dei prodotti nei processi a base acquosa. Per affrontare queste sfide, lo sviluppo di estratti pronti all'uso emerge come una soluzione praticabile6.
I polioli sono spesso utilizzati nelle formulazioni cosmetiche come umettanti a causa della loro buona polarità e capacità di trattenere l'umidità dall'ambiente7. Inoltre, polioli come glicerina, glicole propilenico, glicole butilenico, metilpropandiolo, isopentildiolo, glicole pentilenico, 1,2-esandiolo e glicole esilenico possono essere utilizzati per le estrazioni vegetali. Sono considerati solventi non tossici, biodegradabili, ecologici, non reattivi e sicuri per l'uso nell'estrazione delle piante8. Inoltre, i polioli possono resistere al calore generato durante l'estrazione assistita da microonde (MAE) grazie ai loro punti di ebollizione elevati e alla polarità9. Questi polioli sono generalmente riconosciuti come sostanze chimiche sicure (GRAS) dalla Food and Drug Administration (FDA) degli Stati Uniti. A differenza dei solventi convenzionali come l'etanolo o il metanolo, che possono richiedere una rimozione rigorosa dall'estratto a causa dei loro effetti potenzialmente dannosi, i polioli offrono il vantaggio di ridurre al minimo l'energia, il tempo e i costi associati ai processi di rimozione dei solventi10. Ciò non solo semplifica il processo di estrazione, ma migliora anche l'efficienza e la sostenibilità complessive del metodo di estrazione. Precedenti ricerche hanno impiegato polioli come il glicole propilenico e il glicole butilenico come solventi nell'estrazione di composti bioattivi dai fiori di Camellia sinensis 10 e dalla polpa di caffè11, rivelando un potenziale significativo per il loro ruolo come solventi alternativi sostenibili nel processo di estrazione delle piante. Pertanto, il continuo sviluppo e l'ottimizzazione di un sistema solvente poliolo-acqua ha il potenziale per progressi significativi nella chimica verde e nelle pratiche industriali sostenibili.
Generalmente, i composti bioattivi presenti nelle piante sono sintetizzati come metaboliti secondari. Questi composti possono essere classificati in tre gruppi principali: terpeni e terpenoidi, alcaloidi e composti fenolici12. Vari metodi di estrazione vengono utilizzati in diverse condizioni per isolare specifici composti bioattivi dalle piante. I composti bioattivi da materiali vegetali possono essere estratti utilizzando tecniche convenzionali o non convenzionali. I metodi tradizionali includono la macerazione, l'estrazione a riflusso e l'idrodistillazione, mentre i metodi non convenzionali consistono nell'estrazione assistita da ultrasuoni, nell'estrazione assistita da enzimi, nell'estrazione assistita da microonde (MAE), nell'estrazione pulsata assistita da campo elettrico, nell'estrazione di fluidi supercritici e nell'estrazione di liquidi pressurizzati13. Questi metodi non convenzionali sono progettati per migliorare la sicurezza utilizzando solventi e ausiliari più sicuri, migliorando l'efficienza energetica, prevenendo la degradazione dei componenti bioattivi e riducendo l'inquinamento ambientale14.
Inoltre, il MAE è tra le sofisticate tecnologie verdi per l'estrazione di composti bioattivi dalle piante. Le procedure di estrazione convenzionali richiedono una notevole quantità di tempo, energia e temperature elevate, che nel tempo potrebbero degradare i composti bioattivi sensibili al calore13. A differenza delle estrazioni termiche convenzionali, il MAE facilita l'estrazione di composti bioattivi generando un riscaldamento localizzato all'interno del campione, interrompendo le strutture cellulari e migliorando il trasferimento di massa, aumentando così l'efficienza dell'estrazione dei composti. Il calore viene trasferito dall'interno delle cellule vegetali tramite microonde, che operano sulle molecole d'acqua all'interno dei componenti della pianta13. Inoltre, MAE ha fatto progressi per migliorare l'estrazione e la separazione dei composti attivi, aumentando la resa del prodotto, migliorando l'efficienza dell'estrazione, richiedendo meno sostanze chimiche e risparmiando tempo ed energia prevenendo la distruzione dei composti bioattivi15.
Questa ricerca si concentra sull'estrazione di composti fenolici vegetali e antiossidanti naturali attraverso l'estrazione assistita da microonde (MAE) utilizzando diversi tipi di polioli come solventi. Vengono determinati il contenuto fenolico totale (TPC), il contenuto totale di flavonoidi (TFC) e le attività antiossidanti (DPPH, ABTS e FRAP) degli estratti di MAE a base di polioli. Inoltre, il MAE a base di polioli viene confrontato con il MAE utilizzando solventi convenzionali come acqua ed etanolo. Si prevede che questa ricerca contribuirà allo sviluppo di una tecnologia di estrazione sostenibile dal punto di vista ambientale per i componenti naturali, promuovendo la sostenibilità riducendo la dipendenza da sostanze chimiche pericolose, accorciando i tempi di lavorazione e riducendo al minimo il consumo di energia nella produzione di materie prime per potenziali applicazioni nell'industria cosmetica.

<table border="1" fo:keep-together.within-page="1" fo:keep-with-next.within-page="always">
	<tbody>
		<tr>
			<td>1,2-Hexanediol</td>
			<td>Chanjao Longevity Co., Ltd.</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>2,2 -Azino-bis 3 ethylbenzothiazoline-6-sulfonic acid diammonium salt (ABTS)</td>
			<td>Sigma</td>
			<td>A1888</td>
			<td></td>
		</tr>
		<tr>
			<td>2,2-Diphenyl-1-picrylhydrazyl (DPPH)</td>
			<td>Sigma</td>
			<td>D9132</td>
			<td></td>
		</tr>
		<tr>
			<td>2,4,6-Tri(2-pyridyl)-s-triazine (TPTZ)</td>
			<td>Sigma</td>
			<td>93285</td>
			<td></td>
		</tr>
		<tr>
			<td>2-Digital balance</td>
			<td>Ohaus</td>
			<td></td>
			<td>Pioneer</td>
		</tr>
		<tr>
			<td>4-Digital balance</td>
			<td>Denver</td>
			<td>SI-234</td>
			<td></td>
		</tr>
		<tr>
			<td>6-hydroxy-2,5,7,8 tetramethylchroman -2-carboxylic acid (Trolox)</td>
			<td>Sigma</td>
			<td>238813</td>
			<td></td>
		</tr>
		<tr>
			<td>96-well plate</td>
			<td>SPL Life Science</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Absolute ethanol</td>
			<td>RCI Labscan</td>
			<td>64175</td>
			<td></td>
		</tr>
		<tr>
			<td>Acetic acid</td>
			<td>RCI Labscan</td>
			<td>64197</td>
			<td></td>
		</tr>
		<tr>
			<td>Aluminum chloride</td>
			<td>Loba Chemie</td>
			<td>898</td>
			<td></td>
		</tr>
		<tr>
			<td>Automatic pipette</td>
			<td>Labnet</td>
			<td></td>
			<td>Biopett</td>
		</tr>
		<tr>
			<td>Butylene glycol</td>
			<td>Chanjao Longevity Co., Ltd.</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Ethos X advanced microwave extraction</td>
			<td>Milestone Srl, Sorisole, Italy</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Ferrous sulfate</td>
			<td>Ajex Finechem</td>
			<td>3850</td>
			<td></td>
		</tr>
		<tr>
			<td>Folin-Ciocalteu&#39;s reagent</td>
			<td>Loba Chemie</td>
			<td>3870</td>
			<td></td>
		</tr>
		<tr>
			<td>Freezer SF</td>
			<td>Sanyo</td>
			<td>C697(GYN)</td>
			<td></td>
		</tr>
		<tr>
			<td>Gallic acid</td>
			<td>Sigma</td>
			<td>398225</td>
			<td></td>
		</tr>
		<tr>
			<td>Grinder</td>
			<td>Ou Hardware Products Co.,Ltd</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Hexylene glycol</td>
			<td>Chanjao Longevity Co., Ltd.</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Hydrochloric acid (37%)</td>
			<td>RCI Labscan</td>
			<td>AR1107</td>
			<td></td>
		</tr>
		<tr>
			<td>Iron (III) chloride</td>
			<td>Loba Chemie</td>
			<td>3820</td>
			<td></td>
		</tr>
		<tr>
			<td>Isopentyldiol</td>
			<td>Chanjao Longevity Co., Ltd.</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Methanol</td>
			<td>RCI Labscan</td>
			<td>67561</td>
			<td></td>
		</tr>
		<tr>
			<td>Methylpropanediol&#160;</td>
			<td>Chanjao Longevity Co., Ltd.</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Pentylene glycol</td>
			<td>Chanjao Longevity Co., Ltd.</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Potassium persulfate</td>
			<td>Loba Chemie</td>
			<td>5420</td>
			<td></td>
		</tr>
		<tr>
			<td>Propylene glycol</td>
			<td>Chanjao Longevity Co., Ltd.</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Quercetin</td>
			<td>Sigma</td>
			<td>Q4951</td>
			<td></td>
		</tr>
		<tr>
			<td>Refrigerated centrifuge</td>
			<td>Hettich</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Sodium acetate</td>
			<td>Loba Chemie</td>
			<td>5758</td>
			<td></td>
		</tr>
		<tr>
			<td>Sodium carbonate</td>
			<td>Loba Chemie</td>
			<td>5810</td>
			<td></td>
		</tr>
		<tr>
			<td>Sodium hydroxide</td>
			<td>RCI Labscan</td>
			<td>AR1325</td>
			<td></td>
		</tr>
		<tr>
			<td>Sodium nitrite</td>
			<td>Loba Chemie</td>
			<td>5954</td>
			<td></td>
		</tr>
		<tr>
			<td>SPECTROstar Nano microplate reader</td>
			<td>BMG- LABTECH</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>SPSS software</td>
			<td>IBM SPSS Statistics 20</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Tray dryer</td>
			<td>France Etuves</td>
			<td>XUE343</td>
			<td></td>
		</tr>
	</tbody>
</table>

microwave-assisted extraction of phenolic compounds and antioxidants for cosmetic applications using polyol-based technology

L'utilizzo di polioli come solventi verdi per l'estrazione di composti bioattivi da materiali vegetali ha attirato l'attenzione grazie alla loro sicurezza e al loro comportamento inerte con sostanze chimiche bioattive vegetali. Questo studio esplora l'estrazione sostenibile di composti fenolici e antiossidanti naturali dal silverskin del caffè utilizzando il metodo dell'estrazione assistita da microonde (MAE) con solventi a base di polioli: glicerina, glicole propilenico (PG), glicole butilenico (BG), metilpropandiolo (MPD), isopentildiolo (IPD), glicole pentilenico, 1,2-esandiolo e glicole esilenico (HG). È stata condotta un'analisi comparativa sulle estrazioni convenzionali e non convenzionali con solventi, concentrandosi sul loro impatto sui composti bioattivi del MAE, comprendendo parametri come il contenuto fenolico totale (TPC), il contenuto totale di flavonoidi (TFC) e le attività antiossidanti come il saggio di eliminazione dei radicali 1,1-difenil-2-pirilidrazil (DPPH), il saggio di eliminazione dei radicali 2,2'-azino-bis(-3-etilbenzotiazolina-6-acido solfonico) (ABTS) e il saggio del potere antiossidante riducente ferrico (FRAP). I valori più elevati sono stati osservati per TPC con estrazione acquosa-1,2-esandiolo (campione da 52,0 ± 3,0 mg GAE/g), TFC con estrazione acquosa-1,2-esandiolo (campione da 20,0 ± 1,7 mg QE/g), DPPH con estrazione acquosa da HG (campione da 13,6 ± 0,3 mg TE/g), ABTS con estrazione acquosa di glicole pentilenico (campione da 8,2 ± 0,1 mg TE/g) e FRAP con estrazione acquosa da HG (campione da 21,1 ± 1,3 mg Fe (II) E/g). Questa ricerca mira a far progredire la tecnologia di estrazione ecologica attraverso componenti vegetali naturali, promuovendo la sostenibilità riducendo al minimo l'uso di sostanze chimiche pericolose e riducendo il consumo di tempo ed energia, con potenziali applicazioni nei cosmetici.

Nowadays, there is a global trend towards environmental awareness in the beauty industry, leading manufacturers to focus on green technology for extracting plant components using sustainable alternatives1. Typically, traditional solvents such as ethanol, methanol, and hexane are used to extract plant phenolic components and natural antioxidants2. Nevertheless, the presence of solvent residues within plant extracts poses a potential risk to human health, inducing skin and eye irritation3, particularly concerning their intended application in cosmetics. Consequently, it is challenging to eliminate such solvent residues from the extracts, a process that demands considerable investment in time, energy, and human resources4. Recently, superheated water, ionic liquids, deep eutectic solvents, and bio-derived solvents have emerged as promising approaches for green solvent extraction5. However, their use is still limited by product separation in aqueous-based processes. To address these challenges, the development of ready-to-use extracts emerges as a viable solution6.
Polyols are often used in cosmetic formulations as humectants because of their good polarity and ability to retain moisture from the environment7. In addition, polyols such as glycerin, propylene glycol, butylene glycol, methylpropanediol, isopentyldiol, pentylene glycol, 1,2-hexanediol, and hexylene glycol can be utilized for plant extractions. They are considered non-toxic, biodegradable, environmentally friendly, non-reactive, and safe solvents for use in plant extraction8. Additionally, polyols can withstand the heat generated during microwave-assisted extraction (MAE) due to their elevated boiling points and polarity9. These polyols are generally recognized as safe (GRAS) chemicals by the United States Food and Drug Administration (FDA). Unlike conventional solvents such as ethanol or methanol, which may require rigorous removal from the extract due to their potentially harmful effects, polyols offer the advantage of minimizing the energy, time, and costs associated with solvent removal processes10. This not only streamlines the extraction process but also enhances the overall efficiency and sustainability of the extraction method. Previous investigations have employed polyols such as propylene glycol and butylene glycol as solvents in the extraction of bioactive compounds from Camellia sinensis flowers10 and coffee pulp11, revealing significant potential for their role as sustainable alternative solvents in the plant extraction process. Thus, the continued development and optimization of a polyols-water solvent system holds the potential for significant advancements in green chemistry and sustainable industrial practices.
Generally, bioactive compounds found in plants are synthesized as secondary metabolites. These compounds can be categorized into three primary groups: terpenes and terpenoids, alkaloids, and phenolic compounds12. Various extraction methods are utilized under different conditions to isolate specific bioactive compounds from plants. Bioactive compounds from plant materials can be extracted using either conventional or non-conventional techniques. Traditional methods include maceration, reflux extraction, and hydro-distillation, while non-conventional methods consist of ultrasound-assisted extraction, enzyme-assisted extraction, microwave-assisted extraction (MAE), pulsed electric field-assisted extraction, supercritical fluid extraction, and pressurized liquid extraction13. These non-conventional methods are designed to enhance safety by utilizing safer solvents and auxiliaries, improving energy efficiency, preventing degradation of the bioactive components, and reducing environmental pollution14.
Furthermore, MAE is among the sophisticated green technologies for extracting bioactive compounds from plants. Conventional extraction procedures require significant amounts of time, energy, and high temperatures, which over time might degrade heat-sensitive bioactive compounds13. In contrast to conventional thermal extractions, MAE facilitates the extraction of bioactive compounds by generating localized heating within the sample, disrupting cell structures, and enhancing mass transfer, thereby increasing the efficiency of compound extraction. Heat is transferred from inside the plant cells by microwaves, which operate on the water molecules within the plant components13. Moreover, MAE has advanced to improve the extraction and separation of active compounds, increasing product yield, enhancing extraction efficiency, requiring fewer chemicals, and saving time and energy while preventing the destruction of bioactive compounds15.
This research focuses on the extraction of plant phenolic compounds and natural antioxidants through microwave-assisted extraction (MAE) using different types of polyols as solvents. The total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activities (DPPH, ABTS, and FRAP) of polyol-based MAE extracts are determined. Additionally, polyol-based MAE is compared with MAE using conventional solvents such as water and ethanol. This research is expected to contribute to the development of environmentally sustainable extraction technology for natural components, promoting sustainability by reducing reliance on hazardous chemicals, shortening processing times, and minimizing energy consumption in raw material production for potential applications within the cosmetics industry.

Autore in primo piano: Estrazione ecologica di composti bioattivi utilizzando tecniche assistite da microonde a base di polioli

Estrazione assistita da microonde di composti fenolici e antiossidanti per applicazioni cosmetiche utilizzando la tecnologia a base di polioli

This research talks about finding eco-friendly ways to extract plant bioactive compounds. We are testing how well microwave assisted extraction with the polyol-based solvents work for extracting plants bioactive substances, especially phenol compounds. Additionally, exploring this method could lead to more efficient and effective extraction technique for the cosmetic industries.Today's cosmetic research is also about using green technology and green chemistry. Nonconventional extraction techniques such as microwave-assist extraction, and extraction, have been interestingly employed to extract plants bioactive compounds. However, organic solvents are still commonly utilized for bioactive component extraction.Using polyol-based solvent for microwave assistant extraction turned out to be more effective than using traditional solvent like water and ethanol. The results show that the plant extract obtained with polyol have higher level of phenolic content for the flavanoid content and antioxidant activity. Compared to those extracted with conventional solvent.Our procedure stands out because it is beneficial, environmentally friendly and safe for human health. It is also more energy efficient and cost effective than traditional processes, making it an excellent alternative for sustainable and simple production. Our finding show that polyols combined with unconventional extraction methods can extract phenol compounds.The next challenge is whether this extraction method can be used to extract other plant, secondary metabolized, and if it can be commercialized to extract bioactive compounds for cosmetic purposes.

Effetto dei solventi polioli e dei solventi convenzionali sul contenuto fenolico totale, sul contenuto totale di flavonoidi, sui dosaggi antiossidanti DPPH, FRAP e ABTS La polarità del solvente deve essere compatibile con quella delle molecole attive mirate per migliorare l'efficienza di estrazione delle sostanze bioattive dalle piante22. Gli esperimenti sono stati condotti utilizzando vari solventi (acqua, etanolo, glicerina, glicole propilenico, glicole butilenico, metilprop...

Questo protocollo descrive in dettaglio l'utilizzo di un metodo di estrazione a microonde a base di polioli per l'estrazione di composti fenolici e antiossidanti naturali, che rappresenta un approccio pratico ed ecosostenibile allo sviluppo di estratti pronti all'uso.

The utilization of polyols as green solvents for extracting bioactive compounds from plant materials has gained attention due to their safety and inert ...

microwave-assisted-extraction-phenolic-compounds-antioxidants-for

Research

JoVE Journal

Chemistry

Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology

504 Views.  Mae Fah Laung University. This research talks about finding eco-friendly ways to extract plant bioactive compounds. We are testing how well microwave assisted extraction with the polyol-based solvents work for extracting plants bioactive substances, especially phenol compounds. Additionally, exploring this method could lead to more efficient and effective extraction technique for the cosmetic industries.Today's cosmetic research is also about using green technology and green chemistry. Nonconventional extractio...