Name: targeted expression of gfp in the hair follicle using ex vivo viral transduction
Uploaded: 2008-03-17T19:30:00
Duration: 5 min 28 s
Description: Watch this Scientific Journal Video about Targeted Expression of GFP in the Hair Follicle Using Ex Vivo Viral Transduction at JoVE.com

Für weitere Informationen über gezielte Expression von GFP in den Haarfollikel mit ex vivo viralen transductionplease, besuchen <a href="http://www.springerprotocols.com/">Springer Protocols</a> .

The authors have nothing to disclose.

A correction was made to: <a href="http://www.jove.com/video/708">Targeted expression of GFP in the hair follicle using ex vivo viral transduction</a>. A revised abstract was republished due to a publisher error. The correct abstract is:
There are many cell types in the hair follicle, including hair matrix cells which form the hair shaft and stem cells which can initiate the hair shaft during early anagen, the growth phase of the hair cycle, as well as pluripotent stem cells that play a role in hair follicle growth but have the potential to differentiate to non-follicle cells such as neurons. These properties of the hair follicle are discussed. The various cell types of the hair follicle are potential targets for gene therapy. Gene delivery system for the hair follicle using viral vectors or liposomes for gene targeting to the various cell types in the hair follicle and the results obtained are also discussed. 
This replaced:
The hair follicle is a highly complex appendage of the skin containing a multiplicity of cell types. The follicle undergoes constant cycling through the life of the organism including growth and resorption with growth dependent on specific stem cells. The targeting of the follicle by genes and stem cells to change its properties, in particular, the nature of the hair shaft is, discussed. Hair follicle delivery systems are described, such as liposomes and viral vectors for gene therapy. The nature of the hair follicle stem cells is discussed, in particular, its pluripotency.

A correction was made to: <a href="http://www.jove.com/video/708">Targeted expression of GFP in the hair follicle using ex vivo viral transduction</a>. A revised abstract was republished due to a publisher error.

Erratum: Targeted Expression of GFP in the Hair Follicle Using Ex Vivo Viral Transduction

targeted expression of gfp in the hair follicle using ex vivo viral transduction

Der Haarfollikel ist ein hochkomplexes Anhängsel der Haut mit einer Vielzahl von Zelltypen. Der Follikel wird ständig dem Fahrrad durch das Leben des Organismus einschließlich Wachstum und Resorption mit einem Wachstum abhängig von bestimmten Stammzellen. Die Ausrichtung der Follikel durch Gene und Stammzellen, um seine Eigenschaften zu ändern, insbesondere die Art der Haarschaft ist, diskutiert. Haarfollikel-Delivery-Systeme beschrieben werden, wie Liposomen und virale Vektoren für die Gentherapie. Die Art der Haarfollikel-Stammzellen diskutiert, insbesondere ihre Pluripotenz.

Watch this Scientific Journal Video about Targeted Expression of GFP in the Hair Follicle Using Ex Vivo Viral Transduction at JoVE.com

Targeted Expression of GFP in the Hair Follicle Using Ex Vivo Viral Transduction

Gezielte Expression von GFP in den Haarfollikel mit Ex Vivo viralen Transduktion

There are many cell types in the hair follicle, including hair matrix cells which form the hair shaft and stem cells which can initiate the hair shaft ...

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