Name: morris water maze experiment
Uploaded: 2008-09-24T00:00:00
Description: Watch this Scientific Journal Video about Morris Water Maze Experiment at JoVE.com

JLN MH 68.347 tarafından desteklenmiştir.

Su labirenti ayarlama <ol><li> Su labirenti kurmak ana bileşeni, 6 metre çapında ve 3 metre derin hakkında hakkında, yuvarlak bir havuz olmalıdır. Görev, bir video kamera ile kayıt yapıyorsanız, labirentin tüm tarafların kameranın görüş alanı içinde olduğundan emin olun. </li><li> 26 yakın olmalıdır musluk suyu, ° C ile su labirenti doldurun Bu birkaç saat sürebilir, bu nedenle önceden çok iyi yapılmalıdır. 26 ° C derece içinde bir şekilde periyodik olarak su sıcaklığı kontrol </li...

<ol>
	<li>de Bruin, J. P., Swinkels, W. A., de Brabander, J. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Response+learning+of+rats+in+a+Morris+water+maze:+involvement+of+the+medial+prefrontal+cortex.">Response learning of rats in a Morris water maze: involvement of the medial prefrontal cortex.</a> Behav. Brain Res. 85, 47-55 (1997).</li><li>Redish, A. D., Touretzky, D. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+role+of+the+hippocampus+in+solving+the+Morris+water+maze.">The role of the hippocampus in solving the Morris water maze.</a> Neural. Comput. 1, 73-111 (1998).</li><li>D'Hooge, R., De Deyn, P. P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Applications+of+the+Morris+water+maze+in+the+study+of+learning+and+memory.">Applications of the Morris water maze in the study of learning and memory.</a> Brain Res. Rev. 36, 60-90 (2001).</li><li>Kallai, J., Makany, T., Karadi, K., Jacobs, W. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Spatial+orientation+strategies+in+Morris-type+virtual+water+task+for+humans.">Spatial orientation strategies in Morris-type virtual water task for humans.</a> Behav. Brain Res. 159, 187-196 (2005).</li><li>Morris, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Developments+of+a+water-maze+procedure+for+studying+spatial+learning+in+the+rat.">Developments of a water-maze procedure for studying spatial learning in the rat.</a> J. Neurosci. Methods. 11, 47-60 (1984).</li><li>Brandeis, R., Brandys, Y., Yehuda, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+use+of+the+Morris+Water+Maze+in+the+study+of+learning+and+memory.">The use of the Morris Water Maze in the study of learning and memory.</a> Int. J. Neurosci. 48, 26-69 (1989).</li><li>Kesner, R. P., Exans, R. B., Hunt, M. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Further+evidence+in+support+of+the+neurobiological+bases+of+an+attribute+model+of+memory:+role+of+the+hippocampus.">Further evidence in support of the neurobiological bases of an attribute model of memory: role of the hippocampus.</a> Int. J. Neurosci. 21-22, 21-22 (1987-8).</li><li>Jarrard, L. E., Okaichi, H., Steward, O., Goldschmidt, R. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=On+the+role+of+hippocampal+connections+in+the+performance+of+place+and+cue+tasks:+comparisons+with+damage+to+the+hippocampus.">On the role of hippocampal connections in the performance of place and cue tasks: comparisons with damage to the hippocampus.</a> Behav. Neurosci. 98, 946-954 (1984).</li><li>Hodges, H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Maze+procedures:+the+radial-arm+and+water+maze+compared.">Maze procedures: the radial-arm and water maze compared.</a> Cogn. Brain Res. 3, 167-181 (1996).</li><li>Shumake, J., Gonzalez-Lima, F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Brain+systems+underlying+susceptibility+to+helplessness+and+depression.">Brain systems underlying susceptibility to helplessness and depression.</a> Behav. Cogn. Neurosci. Rev. 2, 198-221 (2003).</li><li>Owen, J. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Physiology+of+the+menstrual+cycle.">Physiology of the menstrual cycle.</a> Am. J. Clin. Nutr. 28, 333-338 (1975).</li><li>Everett, J. W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Neurobiology+of+reproduction+in+the+female+rat.">Neurobiology of reproduction in the female rat.</a> Monogr. Endocrinol. 32, 1-133 (1989).</li><li>Warren, S. G., Humphreys, A. G., Juraska, J. M., Greenough, W. T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=LTP+varies+across+the+estrous+cycle:+enhanced+synaptic+plasticity+in+proestrus+rats.">LTP varies across the estrous cycle: enhanced synaptic plasticity in proestrus rats.</a> Brain Res. 703, 26-30 (1995).</li><li>Warren, S. G., Juraska, J. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Spatial+and+nonspatial+learning+across+the+rat+estrous+cycle.">Spatial and nonspatial learning across the rat estrous cycle.</a> Behav. Neurosci. 111, 259-266 (1997).</li></ol>

Su labirenti görev Morris 5 gelişme olmuştur. Bu görev, çalışma, hafıza, referans bellek ve görev stratejisi 6 araştırmak için çeşitli yolları değişmiş olabilir. Öncesi ve tek bir gün test: Burada açıklanan prosedür su labirenti diğer sürümleri bir sapmayı temsil eden iki kritik değişkenleri içerir. Antrenman öncesi hipokampus 7-8 mekansal / ilişkisel bellek yer almaktadır. Su labirenti, özellikle uzaysal 3 test eder . Ancak, uzaysal içer...

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<td>SMART System</td>
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<td>This system is not a requirement &#x2013; there are many other behavioral systems on the market.</td>
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morris water maze experiment

Morris su labirenti uzamsal bellek ve öğrenme incelemek için yaygın olarak kullanılır. Hayvanlar toz yağsız süt ya da gizli bir kaçış platformu için yüzmek gerekir toksik olmayan sıcaklık boya, opak renkli bir su havuzu yerleştirilir. Opak su olduğundan, hayvanların platform, kaçış yolu bulmak için kokusu üzerine kuramazsınız. Bunun yerine, dış / ekstra labirent ipuçları güvenmek gerekir. Hayvanlar görev daha aşina hale geldikçe, daha hızlı platform bulabilirsiniz. Richard G. Morris tarafından 1984 yılında geliştirilen bu paradigma davranışsal sinirbilim &quot;altın standart&quot; biri haline gelmiştir.

Watch this Scientific Journal Video about Morris Water Maze Experiment at JoVE.com

Morris Water Maze Experiment

Morris su labirenti davranışsal bir görev hipokampus katılımı belgelemek için kullanılan bir iyi kabul edilen bir araçtır.

Morris Su Labirent Deney

The Morris water maze is widely used to study spatial memory and learning. Animals are placed in a pool of water that is colored opaque with powdered ...

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