Carine Fillebeen

Redox control of iron regulatory proteins.

A phosphomimetic mutation at Ser-138 renders iron regulatory protein 1 sensitive to iron-dependent degradation.

IRP1 Ser-711 is a phosphorylation site, critical for regulation of RNA-binding and aconitase activities.

Iron inactivates the RNA polymerase NS5B and suppresses subgenomic replication of hepatitis C Virus.

Sodium nitroprusside promotes IRP2 degradation via an increase in intracellular iron and in the absence of S nitrosylation at C178.

Overexpression of iron regulatory protein 1 suppresses growth of tumor xenografts.

Iron-dependent degradation of apo-IRP1 by the ubiquitin-proteasome pathway.

Expression of the subgenomic hepatitis C virus replicon alters iron homeostasis in Huh7 cells.

HO-1-mediated macroautophagy: a mechanism for unregulated iron deposition in aging and degenerating neural tissues.

Iron absorption and distribution in TNF(DeltaARE/+) mice, a model of chronic inflammation.

Iron inhibits replication of infectious hepatitis C virus in permissive Huh7.5.1 cells.

Unregulated brain iron deposition in transgenic mice over-expressing HMOX1 in the astrocytic compartment.

Hepatitis C virus infection causes iron deficiency in Huh7.5.1 cells.

Iron-dependent regulation of hepcidin in Hjv-/- mice: evidence that hemojuvelin is dispensable for sensing body iron levels.