Zhongxiao Wang

Department of Ophthalmology,
Boston Children's Hospital,
Boston Children’s Hospital,
Department of Ophthalmology, Boston Children's Hospital,
Department of Ophthalmology, Boston Children’s Hospital

Harvard Medical School

BIOGRAPHY

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PUBLICATIONS

Nanoparticle-mediated expression of a Wnt pathway inhibitor ameliorates ocular neovascularization.

Arteriosclerosis, thrombosis, and vascular biology Apr, 2015 | Pubmed ID: 25657312

Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization.

Arteriosclerosis, thrombosis, and vascular biology 09, 2016 | Pubmed ID: 27417579

Neurovascular cross talk in diabetic retinopathy: Pathophysiological roles and therapeutic implications.

American journal of physiology. Heart and circulatory physiology Sep, 2016 | Pubmed ID: 27473938

Pharmacologic Activation of Wnt Signaling by Lithium Normalizes Retinal Vasculature in a Murine Model of Familial Exudative Vitreoretinopathy.

The American journal of pathology 10, 2016 | Pubmed ID: 27524797

Retinal expression of small non-coding RNAs in a murine model of proliferative retinopathy.

Scientific reports Sep, 2016 | Pubmed ID: 27653551

Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis.

EBioMedicine Nov, 2016 | Pubmed ID: 27720395

FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice.

Cell reports 02, 2017 | Pubmed ID: 28199833

Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos.

The Journal of experimental medicine 06, 2017 | Pubmed ID: 28465464

RORα modulates semaphorin 3E transcription and neurovascular interaction in pathological retinal angiogenesis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 10, 2017 | Pubmed ID: 28646017

Animal models of ocular angiogenesis: from development to pathologies.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 11, 2017 | Pubmed ID: 28739642

Adiponectin Mediates Dietary Omega-3 Long-Chain Polyunsaturated Fatty Acid Protection Against Choroidal Neovascularization in Mice.

Investigative ophthalmology & visual science 08, 2017 | Pubmed ID: 28763559

Photoreceptor glucose metabolism determines normal retinal vascular growth.

EMBO molecular medicine 01, 2018 | Pubmed ID: 29180355

Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice.

Diabetes 05, 2018 | Pubmed ID: 29487115

Wnt Signaling in vascular eye diseases.

Progress in retinal and eye research Dec, 2018 | Pubmed ID: 30513356

MicroRNA-145 Regulates Pathological Retinal Angiogenesis by Suppression of TMOD3.

Molecular therapy. Nucleic acids Mar, 2019 | Pubmed ID: 30981984

Long-Acting FGF21 Inhibits Retinal Vascular Leakage in In Vivo and In Vitro Models.

International journal of molecular sciences Feb, 2020 | Pubmed ID: 32054022

Targeting Neurovascular Interaction in Retinal Disorders.

International journal of molecular sciences Feb, 2020 | Pubmed ID: 32098361

Wnt signaling activates MFSD2A to suppress vascular endothelial transcytosis and maintain blood-retinal barrier.

Science advances 08, 2020 | Pubmed ID: 32923627

Editorial: Novel Therapeutic Target and Drug Development in Neurovascular Retinal Diseases.

Frontiers in pharmacology , 2021 | Pubmed ID: 33935774

Wnt Signaling in Inner Blood-Retinal Barrier Maintenance.

International journal of molecular sciences Nov, 2021 | Pubmed ID: 34769308

REV-ERBα regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF2.

Redox biology 05, 2022 | Pubmed ID: 35176707

INSTITUTIONS

Harvard Medical School

JOVE ARTICLES

Assessment and Characterization of Hyaloid Vessels in Mice

Zhongxiao Wang¹,

Chi-Hsiu Liu¹,

Shuo Huang¹,

Jing Chen^1,2

¹Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School,

²The Manton Center for Orphan Disease Research, Boston Children's Hospital, Harvard Medical School

Medicine

Endothelial Cell Transcytosis Assay as an In Vitro Model to Evaluate Inner Blood-Retinal Barrier Permeability

Kiran Bora^*,1,

Zhongxiao Wang^*,1,

Felix Yemanyi¹,

Meenakshi Maurya¹,

Alexandra K. Blomfield¹,

Yohei Tomita¹,

Jing Chen¹

¹Department of Ophthalmology, Boston Children’s Hospital, Harvard Medical School

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Zhongxiao Wang

Department of Ophthalmology,Boston Children's Hospital,Boston Children’s Hospital,Department of Ophthalmology, Boston Children's Hospital,Department of Ophthalmology, Boston Children’s Hospital

Harvard Medical School

Assessment and Characterization of Hyaloid Vessels in Mice

Endothelial Cell Transcytosis Assay as an In Vitro Model to Evaluate Inner Blood-Retinal Barrier Permeability

Department of Ophthalmology,
Boston Children's Hospital,
Boston Children’s Hospital,
Department of Ophthalmology, Boston Children's Hospital,
Department of Ophthalmology, Boston Children’s Hospital