Laurence A. Angel
Department of Chemistry
Texas A&M University-Commerce
Laurence Angel is a Professor in the Chemistry Department of Texas A&M - Commerce. He received his undergraduate with honors degree and a Ph.D. from the Chemistry Department of the University of Sussex, UK, where he applied mass spectrometry techniques for investigating the reactions of atmospheric ions in association with water clusters.
As a post-doctoral fellow, in Kent Ervin’s lab, and as an assistant research professor in the Department of Chemistry at the University of Nevada, he studied gas-phase ion chemistry using guided ion beam tandem mass spectrometry techniques for SN2 and combustion reactions.
Dr. Angel joined the faculty of the Chemistry Department at Texas A&M – Commerce in 2007 as an analytical/instrumental chemist and has developed an expertise in the use of ion mobility - mass spectrometry and molecular modeling to analyze designed metallopeptides which have potential as therapeutics for controlling the progression of cancers and metal homeostatic imbalance diseases.
Ion mobility mass spectrometry of Au25(SCH2CH2Ph)18 nanoclusters.
ACS nano Aug, 2010 | Pubmed ID: 20731448
Effects of transition metal ion identity and π-cation interactions in metal-bis(peptide) complexes containing phenylalanine.
European journal of mass spectrometry (Chichester, England) , 2010 | Pubmed ID: 21173465
Ion mobility-mass spectrometry study of folded ubiquitin conformers induced by treatment with cis-[Pd(en)(H2O2]2+.
Journal of the American Society for Mass Spectrometry Feb, 2011 | Pubmed ID: 21472589
Study of metal ion labeling of the conformational and charge states of lysozyme by ion mobility mass spectrometry.
European journal of mass spectrometry (Chichester, England) , 2011 | Pubmed ID: 21828412
Analysis of methanobactin from Methylosinus trichosporium OB3b via ion mobility mass spectrometry.
European journal of mass spectrometry (Chichester, England) , 2012 | Pubmed ID: 23654196
The pH dependent Cu(II) and Zn(II) binding behavior of an analog methanobactin peptide.
European journal of mass spectrometry (Chichester, England) , 2013 | Pubmed ID: 24378464
Redox activity and multiple copper(I) coordination of 2His-2Cys oligopeptide.
Journal of mass spectrometry : JMS Feb, 2015 | Pubmed ID: 25800013
Probing the stability of insulin oligomers using electrospray ionization ion mobility mass spectrometry.
European journal of mass spectrometry (Chichester, England) , 2015 | Pubmed ID: 26764306
The multiple conformational charge states of zinc(II) coordination by 2His-2Cys oligopeptide investigated by ion mobility-mass spectrometry, density functional theory and theoretical collision cross sections.
Journal of mass spectrometry : JMS Dec, 2016 | Pubmed ID: 27594546
Applying Ion Mobility-Mass Spectrometry Techniques for Explicitly Identifying the Products of Cu(II) Reactions of 2His-2Cys Motif Peptides.
Analytical chemistry 11, 2016 | Pubmed ID: 27740744
Binding Selectivity of Methanobactin from Methylosinus trichosporium OB3b for Copper(I), Silver(I), Zinc(II), Nickel(II), Cobalt(II), Manganese(II), Lead(II), and Iron(II).
Journal of the American Society for Mass Spectrometry 12, 2017 | Pubmed ID: 28856622
Direct Dynamics Simulations of Fragmentation of a Zn(II)-2Cys-2His Oligopeptide. Comparison with Mass Spectrometry Collision-Induced Dissociation.
The journal of physical chemistry. A Aug, 2019 | Pubmed ID: 31327226
Weak Acid-Base Interactions of Histidine and Cysteine Affect the Charge States, Tertiary Structure, and Zn(II)-Binding of Heptapeptides.
Journal of the American Society for Mass Spectrometry Oct, 2019 | Pubmed ID: 31332742
Comparison of the pH-dependent formation of His and Cys heptapeptide complexes of nickel(II), copper(II), and zinc(II) as determined by ion mobility-mass spectrometry.
Journal of mass spectrometry : JMS Mar, 2020 | Pubmed ID: 31881105
Collisional dynamics simulations revealing fragmentation properties of Zn(ii)-bound poly-peptide.
Physical chemistry chemical physics : PCCP Jul, 2020 | Pubmed ID: 32596702
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