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Auckland Bioengineering Institute
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A thermodynamic model of the cardiac sarcoplasmic/endoplasmic Ca(2+) (SERCA) pump.
Biophysical journal Mar, 2009 | Pubmed ID: 19254563
Why has reversal of the actin-myosin cross-bridge cycle not been observed experimentally?
Journal of applied physiology (Bethesda, Md. : 1985) Jun, 2010 | Pubmed ID: 20133436
A metabolite-sensitive, thermodynamically constrained model of cardiac cross-bridge cycling: implications for force development during ischemia.
Biophysical journal Jan, 2010 | Pubmed ID: 20338848
Streptozotocin-induced diabetes prolongs twitch duration without affecting the energetics of isolated ventricular trabeculae.
Cardiovascular diabetology Apr, 2014 | Pubmed ID: 24731754
Reduced mechanical efficiency in left-ventricular trabeculae of the spontaneously hypertensive rat.
Physiological reports Nov, 2014 | Pubmed ID: 25413328
Regulation of cardiac cellular bioenergetics: mechanisms and consequences.
Physiological reports Jul, 2015 | Pubmed ID: 26229005
Semantics-Based Composition of Integrated Cardiomyocyte Models Motivated by Real-World Use Cases.
PloS one , 2015 | Pubmed ID: 26716837
Myocardial energetics is not compromised during compensated hypertrophy in the Dahl salt-sensitive rat model of hypertension.
American journal of physiology. Heart and circulatory physiology Sep, 2016 | Pubmed ID: 27402668
Does the intercept of the heat-stress relation provide an accurate estimate of cardiac activation heat?
The Journal of physiology 07, 2017 | Pubmed ID: 28455843
Experimental and modelling evidence of shortening heat in cardiac muscle.
The Journal of physiology Oct, 2017 | Pubmed ID: 28771742
Left-Ventricular Energetics in Pulmonary Arterial Hypertension-Induced Right-Ventricular Hypertrophic Failure.
Frontiers in physiology , 2017 | Pubmed ID: 29375394
Bond graph modelling of the cardiac action potential: implications for drift and non-unique steady states.
Proceedings. Mathematical, physical, and engineering sciences Jun, 2018 | Pubmed ID: 29977132
A thermodynamic framework for modelling membrane transporters.
Journal of theoretical biology 11, 2019 | Pubmed ID: 30273576
Insights on the impact of mitochondrial organisation on bioenergetics in high-resolution computational models of cardiac cell architecture.
PLoS computational biology 12, 2018 | Pubmed ID: 30517098
The slow force response to stretch: Controversy and contradictions.
Acta physiologica (Oxford, England) 05, 2019 | Pubmed ID: 30614655
Solving a century-old conundrum underlying cardiac force-length relations.
American journal of physiology. Heart and circulatory physiology 04, 2019 | Pubmed ID: 30707611
Energy expenditure for isometric contractions of right and left ventricular trabeculae over a wide range of frequencies at body temperature.
Scientific reports 06, 2019 | Pubmed ID: 31222042
Energetics Equivalent of the Cardiac Force-Length End-Systolic Zone: Implications for Contractility and Economy of Contraction.
Frontiers in physiology , 2019 | Pubmed ID: 32038302
Re-visiting the Frank-Starling nexus.
Progress in biophysics and molecular biology 01, 2021 | Pubmed ID: 32407748
Insights From Computational Modeling Into the Contribution of Mechano-Calcium Feedback on the Cardiac End-Systolic Force-Length Relationship.
Frontiers in physiology , 2020 | Pubmed ID: 32547426
Disruption of transverse-tubular network reduces energy efficiency in cardiac muscle contraction.
Acta physiologica (Oxford, England) 02, 2021 | Pubmed ID: 32757472
Thermodynamic inconsistency disproves the Suga-Sagawa theory of cardiac energetics.
Progress in biophysics and molecular biology Sep, 2021 | Pubmed ID: 33745881
Hierarchical semantic composition of biosimulation models using bond graphs.
PLoS computational biology 05, 2021 | Pubmed ID: 33983945
Mathematical modeling of myosin, muscle contraction, and movement.
Archives of biochemistry and biophysics Oct, 2021 | Pubmed ID: 34174221
Cardiac mechanical efficiency is preserved in primary cardiac hypertrophy despite impaired mechanical function.
The Journal of general physiology Aug, 2021 | Pubmed ID: 34180944
University of Auckland
Jarrah M. Dowrick1,
Alex J. Anderson1,
Ming L. Cheuk1,
Kenneth Tran1,
Poul M. F. Nielsen1,2,
June-Chiew Han1,
Andrew J. Taberner1,2
1Auckland Bioengineering Institute, University of Auckland,
2Department of Engineering Science, University of Auckland
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