Dan M. Close

490 BioTech, Inc.

BIOGRAPHY

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PUBLICATIONS

Autonomous bioluminescent expression of the bacterial luciferase gene cassette (lux) in a mammalian cell line.

PloS one , 2010 | Pubmed ID: 20805991

Comparison of human optimized bacterial luciferase, firefly luciferase, and green fluorescent protein for continuous imaging of cell culture and animal models.

Journal of biomedical optics Apr, 2011 | Pubmed ID: 21529093

Reporter proteins in whole-cell optical bioreporter detection systems, biosensor integrations, and biosensing applications.

Sensors (Basel, Switzerland) , 2009 | Pubmed ID: 22291559

In vivo bioluminescent imaging (BLI): noninvasive visualization and interrogation of biological processes in living animals.

Sensors (Basel, Switzerland) , 2011 | Pubmed ID: 22346573

INSTITUTIONS

490 BioTech, Inc.

JOVE ARTICLES

Autonomously Bioluminescent Mammalian Cells for Continuous and Real-time Monitoring of Cytotoxicity

Tingting Xu¹,

Dan M. Close²,

James D. Webb³,

Steven A. Ripp^2,3,

Gary S. Sayler^1,2,3

¹The Joint Institute for Biological Sciences, Oak Ridge National Laboratory,

², 490 BioTech, Inc.,

³The Center for Environmental Biotechnology, The University of Tennessee, Knoxville

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