Department of Anesthesiology and Critical Care,
Department of Pharmacology,
Department of Neuroscience,
Center for Sleep and Circadian Neurobiology
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Inducible and brain region-specific CREB transgenic mice.
Molecular pharmacology Jun, 2002 | Pubmed ID: 12021407
Inducible, reversible hair loss in transgenic mice.
Transgenic research Jun, 2002 | Pubmed ID: 12113456
Single-cell antisense RNA amplification and microarray analysis as a tool for studying neurological degeneration and restoration.
Science of aging knowledge environment : SAGE KE Jan, 2002 | Pubmed ID: 14602975
An essential role for DeltaFosB in the nucleus accumbens in morphine action.
Nature neuroscience Feb, 2006 | Pubmed ID: 16415864
High throughput modular chambers for rapid evaluation of anesthetic sensitivity.
BMC anesthesiology , 2006 | Pubmed ID: 17096844
Disruption of diacylglycerol kinase delta (DGKD) associated with seizures in humans and mice.
American journal of human genetics Apr, 2007 | Pubmed ID: 17357084
An essential role for orexins in emergence from general anesthesia.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2008 | Pubmed ID: 18195361
Does it add up?
Anesthesia and analgesia Aug, 2008 | Pubmed ID: 18633009
Anesthetic sensitivity: learning to fly.
Anesthesiology Jul, 2009 | Pubmed ID: 19512880
Halothane-induced hypnosis is not accompanied by inactivation of orexinergic output in rodents.
Anesthesiology Nov, 2009 | Pubmed ID: 19809293
Inhaled anesthetic potency in aged Alzheimer mice.
Anesthesia and analgesia Feb, 2010 | Pubmed ID: 19820240
Opiates, sleep, and pain: the adenosinergic link.
Anesthesiology Dec, 2009 | Pubmed ID: 19934853
A conserved behavioral state barrier impedes transitions between anesthetic-induced unconsciousness and wakefulness: evidence for neural inertia.
PloS one , 2010 | Pubmed ID: 20689589
Time in general anesthesia: depriving the homeostat?
Sleep Dec, 2010 | Pubmed ID: 21120119
Rapid eye movement sleep debt accrues in mice exposed to volatile anesthetics.
Anesthesiology Oct, 2011 | Pubmed ID: 21934405
Is hydrogen sulfide-induced suspended animation general anesthesia?
The Journal of pharmacology and experimental therapeutics Jun, 2012 | Pubmed ID: 22414854
From the edge of oblivion: the dance between intrinsic neuronal currents and neuronal connectivity.
Anesthesiology May, 2012 | Pubmed ID: 22450471
Hypnotic Hypersensitivity to Volatile Anesthetics and Dexmedetomidine in Dopamine β-Hydroxylase Knockout Mice.
Anesthesiology Oct, 2012 | Pubmed ID: 23042227
Direct activation of sleep-promoting VLPO neurons by volatile anesthetics contributes to anesthetic hypnosis.
Current biology : CB Nov, 2012 | Pubmed ID: 23103189
In vivo activation of azipropofol prolongs anesthesia and reveals synaptic targets.
The Journal of biological chemistry Jan, 2013 | Pubmed ID: 23184948
Incidence, predictors and outcomes of postoperative coma: an observational study of 858 606 patients.
European journal of anaesthesiology Aug, 2013 | Pubmed ID: 23344122
Sleep and Anesthesia Interactions: A Pharmacological Appraisal.
Current anesthesiology reports Mar, 2013 | Pubmed ID: 23440738
Enhanced tonic inhibition influences the hypnotic and amnestic actions of the intravenous anesthetics etomidate and propofol.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2013 | Pubmed ID: 23616535
Genetic and anatomical basis of the barrier separating wakefulness and anesthetic-induced unresponsiveness.
PLoS genetics Sep, 2013 | Pubmed ID: 24039590
Orexinergic Activity Modulates Altered Vital Signs and Pituitary Hormone Secretion in Experimental Sepsis.
Critical care medicine Oct, 2013 | Pubmed ID: 24105451
1Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania,
2Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania,
3Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania,
4Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania
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