Stefano Pluchino

Uncovering novel actors in astrocyte-neuron crosstalk in Parkinson's disease: the Wnt/β-catenin signaling cascade as the common final pathway for neuroprotection and self-repair.

Cytokine gene delivery into the central nervous system using intrathecally injected nonreplicative viral vectors.

Vaccination with amyloid-beta peptide induces autoimmune encephalomyelitis in C57/BL6 mice.

Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis.

The therapeutic use of gene therapy in inflammatory demyelinating diseases of the central nervous system.

Gene therapy-mediated modulation of immune processes in the central nervous system.

Cell-based remyelinating therapies in multiple sclerosis: evidence from experimental studies.

Gene therapy for autoimmune diseases.

Neural stem cells and their use as therapeutic tool in neurological disorders.

The therapeutic use of stem cells for myelin repair in autoimmune demyelinating disorders.

Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism.

Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.

Motor evoked potentials in a mouse model of chronic multiple sclerosis.

The therapeutic potential of neural stem cells.

Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury.

Magnetic-resonance-based tracking and quantification of intravenously injected neural stem cell accumulation in the brains of mice with experimental multiple sclerosis.

Neural stem/precursor cells for the treatment of ischemic stroke.

The therapeutic plasticity of neural stem/precursor cells in multiple sclerosis.

Neural stem cells: guardians of the brain.

Neural stem cell-mediated immunomodulation: repairing the haemorrhagic brain.

The MPTP mouse model: cues on DA release and neural stem cell restorative role.

Persistent inflammation alters the function of the endogenous brain stem cell compartment.

Regeneration and repair in multiple sclerosis: the role of cell transplantation.

Immune regulatory neural stem/precursor cells protect from central nervous system autoimmunity by restraining dendritic cell function.

Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms.

Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice.

Human neural stem cells ameliorate autoimmune encephalomyelitis in non-human primates.

Glioma-astrocyte interaction modifies the astrocyte phenotype in a co-culture experimental model.

Co-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in mice.

Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodelling and contralesional pyramidal tract plasticity.

Human ESC-derived neural crest model reveals a key role for SOX2 in sensory neurogenesis.

A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection.

Cyclooxygenase (COX)-1 takes control of adult hippocampal neurogenesis.

Brain regeneration in physiology and pathology: the immune signature driving therapeutic plasticity of neural stem cells.

Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actions.

Transplanted neural stem/precursor cells instruct phagocytes and reduce secondary tissue damage in the injured spinal cord.

New perspectives of tissue remodelling with neural stem and progenitor cell-based therapies.

Plasticity of subventricular zone neuroprogenitors in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease involves cross talk between inflammatory and Wnt/β-catenin signaling pathways: functional consequences for neuroprotection and repair.

Extracellular membrane vesicles and immune regulation in the brain.

Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation.

Wnt your brain be inflamed? Yes, it Wnt!

Aging-induced Nrf2-ARE pathway disruption in the subventricular zone drives neurogenic impairment in parkinsonian mice via PI3K-Wnt/β-catenin dysregulation.

Neuro-immune interactions of neural stem cell transplants: From animal disease models to human trials.

How stem cells speak with host immune cells in inflammatory brain diseases.

The stem cell secretome and its role in brain repair.

Rewiring the ischaemic brain with human-induced pluripotent stem cell-derived cortical neurons.

ISEV position paper: extracellular vesicle RNA analysis and bioinformatics.

Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease.

Peripheral nerve morphogenesis induced by scaffold micropatterning.

Wnt/β-catenin signaling is required to rescue midbrain dopaminergic progenitors and promote neurorepair in ageing mouse model of Parkinson's disease.