Robert J. C. Gilbert

The interaction properties of costimulatory molecules revisited.

O-glycan sialylation and the structure of the stalk-like region of the T cell co-receptor CD8.

Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76.

Three-dimensional structures of translating ribosomes by Cryo-EM.

Crystal structure of a soluble CD28-Fab complex.

Structural basis of pore formation by the bacterial toxin pneumolysin.

Classification and three-dimensional reconstruction of unevenly distributed or symmetry mismatched features of icosahedral particles.

Inactivation and activity of cholesterol-dependent cytolysins: what structural studies tell us.

Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion.

Hepatitis B small surface antigen particles are octahedral.

A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting.

The crystal structure of ORF-9b, a lipid binding protein from the SARS coronavirus.

The C-terminal SH3 domain of CRKL as a dynamic dimerization module transiently exposing a nuclear export signal.

Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates?

Reconfiguration of yeast 40S ribosomal subunit domains by the translation initiation multifactor complex.

Structure of the fungal beta-glucan-binding immune receptor dectin-1: implications for function.

Viral RNA pseudoknots: versatile motifs in gene expression and replication.

Molecular determinants of sphingomyelin specificity of a eukaryotic pore-forming toxin.

The mechanics of translocation: a molecular "spring-and-ratchet" system.

Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2.

Oligomerisation of pneumolysin on cholesterol crystals: similarities to the behaviour of polyene antibiotics.

Ribosomal acrobatics in post-transcriptional control.

RNA pseudoknots and the regulation of protein synthesis.

Peptidoglycan recognition protein-SD provides versatility of receptor formation in Drosophila immunity.

Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1.

Crystal structure of the GluR2 amino-terminal domain provides insights into the architecture and assembly of ionotropic glutamate receptors.

The platelet receptor CLEC-2 is active as a dimer.

Direct observation of distinct A/P hybrid-state tRNAs in translocating ribosomes.

Domain metastability: a molecular basis for immunoglobulin deposition?

Cholesterol-dependent cytolysins.

Human perforin employs different avenues to damage membranes.

Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering.

DNA-templated protein arrays for single-molecule imaging.

Use of the α-mannosidase I inhibitor kifunensine allows the crystallization of apo CTLA-4 homodimer produced in long-term cultures of Chinese hamster ovary cells.

Perforin rapidly induces plasma membrane phospholipid flip-flop.

pH dependence of listeriolysin O aggregation and pore-forming ability.

Perforin activity at membranes leads to invaginations and vesicle formation.

Spacer-length dependence of programmed -1 or -2 ribosomal frameshifting on a U6A heptamer supports a role for messenger RNA (mRNA) tension in frameshifting.

Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase.

Structures of lysenin reveal a shared evolutionary origin for pore-forming proteins and its mode of sphingomyelin recognition.

Effects of MACPF/CDC proteins on lipid membranes.

Biophysical analysis of Kindlin-3 reveals an elongated conformation and maps integrin binding to the membrane-distal β-subunit NPXY motif.

Structural and functional characterization of the kindlin-1 pleckstrin homology domain.

The long and short of microRNA.

Structure of the repulsive guidance molecule (RGM)-neogenin signaling hub.

Structural insights into proteoglycan-shaped Hedgehog signaling.

Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin.

Application of In-Fusion™ cloning for the parallel construction of E. coli expression vectors.