Michel Khrestchatisky

Gelatinase B and TIMP-1 are regulated in a cell- and time-dependent manner in association with neuronal death and glial reactivity after global forebrain ischemia.

TWEAK is expressed by glial cells, induces astrocyte proliferation and increases EAE severity.

[Matrix metalloproteinases and their inhibitors, modulators of neuro-immune interactions and of pathophysiological processes in the nervous system].

Neuronal activity-dependent increase of net matrix metalloproteinase activity is associated with MMP-9 neurotoxicity after kainate.

[The MMP/TIMP system in the nervous system].

Resuscitation of hypoxic piglets with 100% O2 increases pulmonary metalloproteinases and IL-8.

Tissue inhibitor of metalloproteinases-1 (TIMP-1) modulates neuronal death, axonal plasticity, and learning and memory.

Astrocyte reactivity to Fas activation is attenuated in TIMP-1 deficient mice, an in vitro study.

Matrix metalloproteinase-2 (MMP-2) regulates astrocyte motility in connection with the actin cytoskeleton and integrins.

Vesicular trafficking and secretion of matrix metalloproteinases-2, -9 and tissue inhibitor of metalloproteinases-1 in neuronal cells.

TWEAK is expressed at the cell surface of monocytes during multiple sclerosis.

Vitamin D2 potentiates axon regeneration.

Differential vesicular distribution and trafficking of MMP-2, MMP-9, and their inhibitors in astrocytes.

Synthetic therapeutic peptides: science and market.

The human nose harbors a niche of olfactory ectomesenchymal stem cells displaying neurogenic and osteogenic properties.

Resuscitation of hypoxic newborn piglets with supplementary oxygen induces dose-dependent increase in matrix metalloproteinase-activity and down-regulates vital genes.

A new role for TIMP-1 in modulating neurite outgrowth and morphology of cortical neurons.

Developmental vitamin D deficiency alters learning in C57Bl/6J mice.

Mapping of domains on HIV envelope protein mediating association with calnexin and protein-disulfide isomerase.

Severity of experimental autoimmune encephalomyelitis is unexpectedly reduced in mice born to vitamin D-deficient mothers.

Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.

Metzincin proteases and their inhibitors: foes or friends in nervous system physiology?

RAGE-TXNIP axis is required for S100B-promoted Schwann cell migration, fibronectin expression and cytokine secretion.

Resuscitation of newborn piglets. short-term influence of FiO2 on matrix metalloproteinases, caspase-3 and BDNF.

Olfactory stem cells, a new cellular model for studying molecular mechanisms underlying familial dysautonomia.

Drebrin A expression is altered after pilocarpine-induced seizures: time course of changes is consistent for a role in the integrity and stability of dendritic spines of hippocampal granule cells.

Trafficking and secretion of matrix metalloproteinase-2 in olfactory ensheathing glial cells: A role in cell migration?

Engraftment of human nasal olfactory stem cells restores neuroplasticity in mice with hippocampal lesions.

The potential role of metalloproteinases in neurogenesis in the gerbil hippocampus following global forebrain ischemia.

Can the benefits of cannabinoid receptor stimulation on neuroinflammation, neurogenesis and memory during normal aging be useful in AD prevention?

Chemical optimization of new ligands of the low-density lipoprotein receptor as potential vectors for central nervous system targeting.

Medicinal chemistry based approaches and nanotechnology-based systems to improve CNS drug targeting and delivery.

LRP-1--CD44, a new cell surface complex regulating tumor cell adhesion.

Peptide-based vectors for blood-brain barrier targeting and delivery of drugs to the central nervous system.

Evidence for early cognitive impairment related to frontal cortex in the 5XFAD mouse model of Alzheimer's disease.

Role of matrix metalloproteinases in migration and neurotrophic properties of nasal olfactory stem and ensheathing cells.

TWEAK/Fn14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier.

Cholecalciferol (vitamin D₃) improves myelination and recovery after nerve injury.

Area-specific alterations of synaptic plasticity in the 5XFAD mouse model of Alzheimer's disease: dissociation between somatosensory cortex and hippocampus.

Is TWEAK a Biomarker for Autoimmune/Chronic Inflammatory Diseases?

Tissue inhibitor of matrix metalloproteinases-1 loaded poly(lactic-co-glycolic acid) nanoparticles for delivery across the blood-brain barrier.

Onset of hippocampus-dependent memory impairments in 5XFAD transgenic mouse model of Alzheimer's disease.

A unique method for the isolation of nasal olfactory stem cells in living rats.

Dynamic expression of the polysialyltransferase in adult rat hippocampus performing an olfactory associative task.