Mellen Center for Multiple Sclerosis Treatment and Research
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Sex differences in cytokine responses to myelin peptides in multiple sclerosis.
Journal of neuroimmunology Sep, 2002 | Pubmed ID: 12225904
Factors that predict health-related quality of life in patients with relapsing-remitting multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) Feb, 2003 | Pubmed ID: 12617260
Flow cytometric analysis of chemokine receptor expression on cerebrospinal fluid leukocytes.
Methods (San Diego, Calif.) Apr, 2003 | Pubmed ID: 12725798
Expression of CCR2, CCR5, and CXCR3 by CD4+ T cells is stable during a 2-year longitudinal study but varies widely between individuals.
Journal of neurovirology Jun, 2003 | Pubmed ID: 12775413
Interferons in relapsing remitting multiple sclerosis.
Lancet May, 2003 | Pubmed ID: 12781561
Interferon gamma responses to myelin peptides in multiple sclerosis correlate with a new clinical measure of disease progression.
Journal of neuroimmunology Aug, 2003 | Pubmed ID: 12965264
Interferon-beta 1a does not reduce expression of CCR5 and CXCR3 on circulating T cells.
Journal of neuroimmunology Aug, 2003 | Pubmed ID: 12965266
Biologic impact of interferon antibodies, and complexities in assessing their clinical significance.
Neurology Nov, 2003 | Pubmed ID: 14610110
Atrophy is detectable within a 3-month period in untreated patients with active relapsing remitting multiple sclerosis.
Archives of neurology Dec, 2003 | Pubmed ID: 14676048
Multiple sclerosis: disease markers accelerate progress.
Lancet neurology Jan, 2004 | Pubmed ID: 14693099
Impact of disease-modifying therapies on brain and spinal cord atrophy in multiple sclerosis.
Journal of neuroimaging : official journal of the American Society of Neuroimaging Jul, 2004 | Pubmed ID: 15228760
Defining interferon beta response status in multiple sclerosis patients.
Annals of neurology Oct, 2004 | Pubmed ID: 15389896
Association of fatigue and brain atrophy in multiple sclerosis.
Journal of the neurological sciences Feb, 2005 | Pubmed ID: 15694198
Brain atrophy and magnetization transfer ratio following methylprednisolone in multiple sclerosis: short-term changes and long-term implications.
Multiple sclerosis (Houndmills, Basingstoke, England) Apr, 2005 | Pubmed ID: 15794385
Natalizumab: alpha 4-integrin antagonist selective adhesion molecule inhibitors for MS.
Expert review of neurotherapeutics Jul, 2004 | Pubmed ID: 15853576
Eight-year immunogenicity and safety of interferon beta-1a-Avonex treatment in patients with multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) Aug, 2005 | Pubmed ID: 16042223
Effects of sex hormones on costimulatory molecule expression in multiple sclerosis.
Journal of neuroimmunology Oct, 2005 | Pubmed ID: 16046001
Primary progressive multiple sclerosis as a phenotype of a PLP1 gene mutation.
Annals of neurology Sep, 2005 | Pubmed ID: 16130097
Prediction of longitudinal brain atrophy in multiple sclerosis by gray matter magnetic resonance imaging T2 hypointensity.
Archives of neurology Sep, 2005 | Pubmed ID: 16157744
Natalizumab plus interferon beta-1a for relapsing multiple sclerosis.
The New England journal of medicine Mar, 2006 | Pubmed ID: 16510745
Significance of T2 lesions in multiple sclerosis: A 13-year longitudinal study.
Annals of neurology Aug, 2006 | Pubmed ID: 16786526
Should patients with relapsing multiple sclerosis be given a higher dose and frequency of interferon-beta1a?
Nature clinical practice. Neurology Nov, 2005 | Pubmed ID: 16932486
Drug Insight: interferon treatment in multiple sclerosis.
Nature clinical practice. Neurology Jan, 2006 | Pubmed ID: 16932519
Chemokine receptors as biomarkers in multiple sclerosis.
Disease markers , 2006 | Pubmed ID: 17124344
Imaging correlates of axonal swelling in chronic multiple sclerosis brains.
Annals of neurology Sep, 2007 | Pubmed ID: 17427920
Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring.
Lancet neurology May, 2007 | Pubmed ID: 17434098
Interferon-beta for multiple sclerosis: Long-term benefits?
Annals of neurology Apr, 2007 | Pubmed ID: 17444503
Developing a mentorship program for clinical researchers.
The Journal of continuing education in the health professions , 2007 | Pubmed ID: 17576629
Health-related quality of life in multiple sclerosis: effects of natalizumab.
Annals of neurology Oct, 2007 | Pubmed ID: 17696126
Novel interferon-beta-induced gene expression in peripheral blood cells.
Journal of leukocyte biology Nov, 2007 | Pubmed ID: 17709400
Interferon-beta treatment for multiple sclerosis.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics Oct, 2007 | Pubmed ID: 17920544
Biomarkers for interferon response in MS: are we there yet?
Neurology Mar, 2008 | Pubmed ID: 18362268
Gray matter atrophy in multiple sclerosis: a longitudinal study.
Annals of neurology Sep, 2008 | Pubmed ID: 18661561
LINGO-1 antagonists as therapy for multiple sclerosis: in vitro and in vivo evidence.
Expert opinion on biological therapy Oct, 2008 | Pubmed ID: 18774923
Health-related quality of life in multiple sclerosis: current evidence, measurement and effects of disease severity and treatment.
CNS drugs , 2008 | Pubmed ID: 18788835
Gray matter atrophy correlates with MS disability progression measured with MSFC but not EDSS.
Journal of the neurological sciences Jul, 2009 | Pubmed ID: 19100997
Brain atrophy as an outcome measure for multiple sclerosis clinical trials: a "no-brainer"?
Neurology Feb, 2009 | Pubmed ID: 19221291
The efficacy of natalizumab in patients with relapsing multiple sclerosis: subgroup analyses of AFFIRM and SENTINEL.
Journal of neurology Mar, 2009 | Pubmed ID: 19308305
Current approaches to the identification and management of breakthrough disease in patients with multiple sclerosis.
Lancet neurology Jun, 2009 | Pubmed ID: 19446274
Disease modification in multiple sclerosis: issues with relevance to clinical trial designs in Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association Jul, 2006 | Pubmed ID: 19595872
Natalizumab for the treatment of relapsing multiple sclerosis.
Biologics : targets & therapy Jun, 2008 | Pubmed ID: 19707353
Gray-matter injury in multiple sclerosis.
The New England journal of medicine Oct, 2009 | Pubmed ID: 19812410
Do interferon beta-1b and glatiramer acetate grow brain?
Lancet neurology Dec, 2009 | Pubmed ID: 19909906
Heterogeneous, longitudinally stable molecular signatures in response to interferon-beta.
Annals of the New York Academy of Sciences Dec, 2009 | Pubmed ID: 20074275
Natalizumab plus interferon beta-1a reduces lesion formation in relapsing multiple sclerosis.
Journal of the neurological sciences May, 2010 | Pubmed ID: 20236661
A radical proposal: integrate clinical investigation into the U.S. health care system.
Science translational medicine Oct, 2009 | Pubmed ID: 20368168
Patient-centered outcomes: translating clinical efficacy into benefits on health-related quality of life.
Neurology Apr, 2010 | Pubmed ID: 20421570
The multiple sclerosis functional composite: a clinically meaningful measure of disability.
Neurology Apr, 2010 | Pubmed ID: 20421572
Validation of a self-report comorbidity questionnaire for multiple sclerosis.
Neuroepidemiology Aug, 2010 | Pubmed ID: 20551692
Measuring disability in relapsing-remitting MS.
Neurology Jul, 2010 | Pubmed ID: 20592252
Disability progression in a clinical trial of relapsing-remitting multiple sclerosis: eight-year follow-up.
Archives of neurology Nov, 2010 | Pubmed ID: 20625068
Assessment of JC virus DNA in blood and urine from natalizumab-treated patients.
Annals of neurology Sep, 2010 | Pubmed ID: 20737514
Multiple sclerosis: is multiple sclerosis caused by venous insufficiency?
Nature reviews. Neurology Sep, 2010 | Pubmed ID: 20811464
Possible clinical outcome measures for clinical trials in patients with multiple sclerosis.
Therapeutic advances in neurological disorders Jul, 2010 | Pubmed ID: 21179614
Web-based self-management for patients with multiple sclerosis: a practical, randomized trial.
Telemedicine journal and e-health : the official journal of the American Telemedicine Association Jan-Feb, 2011 | Pubmed ID: 21214498
Diagnostic criteria in multiple sclerosis: headed in the right direction but still a ways to go.
Annals of neurology Feb, 2011 | Pubmed ID: 21387367
Beta-interferon for multiple sclerosis.
Experimental cell research May, 2011 | Pubmed ID: 21396360
Challenges to clinical trials in multiple sclerosis: outcome measures in the era of disease-modifying drugs.
Current opinion in neurology Jun, 2011 | Pubmed ID: 21455068
Excessive biologic response to IFNβ is associated with poor treatment response in patients with multiple sclerosis.
PloS one , 2011 | Pubmed ID: 21602934
Oral treatment for multiple sclerosis.
Lancet neurology Nov, 2011 | Pubmed ID: 22014437
The role of cell type-specific responses in IFN-β therapy of multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2011 | Pubmed ID: 22106296
Multiple sclerosis, natalizumab, and PML: helping patients decide.
Cleveland Clinic journal of medicine Nov, 2011 | Pubmed ID: 22123928
Risk stratification and patient counseling for natalizumab in multiple sclerosis.
Neurology Feb, 2012 | Pubmed ID: 22282644
MS clinical trials: what can subgroup analyses teach us?
Lancet neurology May, 2012 | Pubmed ID: 22494954
The elusive biomarker for personalized medicine in multiple sclerosis: the search continues.
Neurology Aug, 2012 | Pubmed ID: 22573625
Multiple sclerosis or multiple possibilities: the continuing problem of misdiagnosis.
Neurology Jun, 2012 | Pubmed ID: 22581931
Early tolerability and safety of fingolimod in clinical practice.
Journal of the neurological sciences Dec, 2012 | Pubmed ID: 23040960
Measurement and clinical effect of grey matter pathology in multiple sclerosis.
Lancet neurology Dec, 2012 | Pubmed ID: 23153407
Time to integrate clinical and research informatics.
Science translational medicine Nov, 2012 | Pubmed ID: 23197569
Predictors of long-term outcome in multiple sclerosis patients treated with interferon β.
Annals of neurology Jan, 2013 | Pubmed ID: 23378325
Author response.
Neurology Feb, 2013 | Pubmed ID: 23544194
Author response to comment on "time to integrate clinical and research informatics".
Science translational medicine Apr, 2013 | Pubmed ID: 23552368
Reliability of classifying multiple sclerosis disease activity using magnetic resonance imaging in a multiple sclerosis clinic.
JAMA neurology Mar, 2013 | Pubmed ID: 23599930
MRI lesions: a surrogate for relapses in multiple sclerosis?
Lancet neurology Jul, 2013 | Pubmed ID: 23743083
Preventing brain atrophy should be the gold standard of effective therapy in MS (after the first year of treatment): Yes.
Multiple sclerosis (Houndmills, Basingstoke, England) Jul, 2013 | Pubmed ID: 23818018
Multiple Sclerosis Outcome Assessments Consortium: Genesis and initial project plan.
Multiple sclerosis (Houndmills, Basingstoke, England) Jan, 2014 | Pubmed ID: 24057430
Assessing treatment response to interferon-β: is there a role for MRI?
Neurology Jan, 2014 | Pubmed ID: 24336144
Defining the clinical course of multiple sclerosis: The 2013 revisions.
Neurology May, 2014 | Pubmed ID: 24871874
Long-term safety and effectiveness of natalizumab redosing and treatment in the STRATA MS Study.
Neurology Jun, 2014 | Pubmed ID: 24898925
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