Department of Medicine
Alexander J. Szalai has not added Biography.
If you are Alexander J. Szalai and would like to personalize this page please email our Author Liaison for assistance.
The antimicrobial activity of C-reactive protein.
Microbes and infection / Institut Pasteur Feb, 2002 | Pubmed ID: 11880053
Experimental allergic encephalomyelitis is inhibited in transgenic mice expressing human C-reactive protein.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2002 | Pubmed ID: 12023381
Varied biologic functions of C-reactive protein: lessons learned from transgenic mice.
Immunologic research , 2002 | Pubmed ID: 12403365
Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae.
Infection and immunity Jan, 2003 | Pubmed ID: 12496151
The biological functions of C-reactive protein.
Vascular pharmacology Aug, 2002 | Pubmed ID: 12616974
Delayed lupus onset in (NZB x NZW)F1 mice expressing a human C-reactive protein transgene.
Arthritis and rheumatism Jun, 2003 | Pubmed ID: 12794828
Fc gamma Rs modulate cytotoxicity of anti-Fas antibodies: implications for agonistic antibody-based therapeutics.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2003 | Pubmed ID: 12847219
Increased thrombosis after arterial injury in human C-reactive protein-transgenic mice.
Circulation Aug, 2003 | Pubmed ID: 12874178
Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface.
Infection and immunity Jan, 2004 | Pubmed ID: 14688088
C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.
Circulation Feb, 2004 | Pubmed ID: 14744975
Evidence for anti-inflammatory activity of statins and PPARalpha activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro.
Blood Jun, 2004 | Pubmed ID: 14976045
Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis.
Journal of neuroscience research Mar, 2004 | Pubmed ID: 14991835
Murine complement C4 is not required for experimental autoimmune encephalomyelitis.
Glia Jan, 2005 | Pubmed ID: 15390104
Effect of low dose atorvastatin versus diet-induced cholesterol lowering on atherosclerotic lesion progression and inflammation in apolipoprotein E*3-Leiden transgenic mice.
Arteriosclerosis, thrombosis, and vascular biology Jan, 2005 | Pubmed ID: 15514207
C-reactive protein (CRP) and autoimmune disease: facts and conjectures.
Clinical & developmental immunology Sep-Dec, 2004 | Pubmed ID: 15559367
The virulence function of Streptococcus pneumoniae surface protein A involves inhibition of complement activation and impairment of complement receptor-mediated protection.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2004 | Pubmed ID: 15585877
Estrogen treatment abrogates neointima formation in human C-reactive protein transgenic mice.
Arteriosclerosis, thrombosis, and vascular biology Oct, 2005 | Pubmed ID: 16051879
C3a expressed in the central nervous system protects against LPS-induced shock.
Neuroscience letters Oct, 2005 | Pubmed ID: 16085360
Complement as a biomarker in multiple sclerosis.
Journal of neuropathology and experimental neurology Aug, 2005 | Pubmed ID: 16106223
Genetic deficiency of C3 as well as CNS-targeted expression of the complement inhibitor sCrry ameliorates experimental autoimmune uveoretinitis.
Experimental eye research Mar, 2006 | Pubmed ID: 16143328
Requirement of the Fc receptor common gamma-chain for gamma delta T cell-mediated promotion of murine experimental autoimmune encephalomyelitis.
European journal of immunology Dec, 2005 | Pubmed ID: 16278814
Complement in BuB/BnJ mice revisited: serum C3 levels and complement opsonic activity are not elevated.
Molecular immunology Apr, 2006 | Pubmed ID: 16310250
Complement and demyelinating disease: no MAC needed?
Brain research reviews Aug, 2006 | Pubmed ID: 16443278
Experimental autoimmune uveitis in the C57BL/6 mouse.
Experimental eye research Jul, 2006 | Pubmed ID: 16524572
Induction of leptin resistance through direct interaction of C-reactive protein with leptin.
Nature medicine Apr, 2006 | Pubmed ID: 16582918
Complement in experimental autoimmune encephalomyelitis revisited: C3 is required for development of maximal disease.
Molecular immunology May, 2007 | Pubmed ID: 17353050
C-reactive protein gene polymorphisms, C-reactive protein blood levels, and cardiovascular disease risk.
Journal of the American College of Cardiology Sep, 2007 | Pubmed ID: 17868801
PspA and PspC minimize immune adherence and transfer of pneumococci from erythrocytes to macrophages through their effects on complement activation.
Infection and immunity Dec, 2007 | Pubmed ID: 17923519
Exaggerated neointima formation in human C-reactive protein transgenic mice is IgG Fc receptor type I (Fc gamma RI)-dependent.
The American journal of pathology Jan, 2008 | Pubmed ID: 18063701
Neointimal formation is reduced after arterial injury in human crp transgenic mice.
Atherosclerosis Nov, 2008 | Pubmed ID: 18358478
Impaired endothelial function in C-reactive protein overexpressing mice.
Atherosclerosis Dec, 2008 | Pubmed ID: 18433756
Immune opsonins modulate BLyS/BAFF release in a receptor-specific fashion.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2008 | Pubmed ID: 18606652
Antibody to the type 3 capsule facilitates immune adherence of pneumococci to erythrocytes and augments their transfer to macrophages.
Infection and immunity Jan, 2009 | Pubmed ID: 19001076
The role of C-reactive protein polymorphisms in inflammation and cardiovascular risk.
Current atherosclerosis reports Mar, 2009 | Pubmed ID: 19228486
C-reactive protein promotes cardiac fibrosis and inflammation in angiotensin II-induced hypertensive cardiac disease.
Hypertension Apr, 2010 | Pubmed ID: 20157054
C-reactive protein-mediated vascular injury requires complement.
Arteriosclerosis, thrombosis, and vascular biology Jun, 2010 | Pubmed ID: 20339115
Complement receptor 1 expression on mouse erythrocytes mediates clearance of Streptococcus pneumoniae by immune adherence.
Infection and immunity Jul, 2010 | Pubmed ID: 20439480
Inhibition of Experimental Autoimmune Encephalomyelitis in Human C-Reactive Protein Transgenic Mice Is FcγRIIB Dependent.
Autoimmune diseases , 2011 | Pubmed ID: 21151582
C-reactive protein promotes acute renal inflammation and fibrosis in unilateral ureteral obstructive nephropathy in mice.
Laboratory investigation; a journal of technical methods and pathology Jun, 2011 | Pubmed ID: 21383672
Collagen-induced arthritis is exacerbated in C-reactive protein-deficient mice.
Arthritis and rheumatism Sep, 2011 | Pubmed ID: 21567377
An about-face for C-reactive protein?
Clinical chemistry Oct, 2011 | Pubmed ID: 21821724
Biomarkers of inflammation and hemostasis associated with left ventricular mass: The Multiethnic Study of Atherosclerosis (MESA).
International journal of molecular epidemiology and genetics , 2011 | Pubmed ID: 22200000
Kidney injury accelerates cystogenesis via pathways modulated by heme oxygenase and complement.
Journal of the American Society of Nephrology : JASN Jul, 2012 | Pubmed ID: 22518005
Associations of C-Reactive Protein to Indices of Vascular Health and the Influence of Serum 25(OH)D Status in Healthy Adults.
Journal of nutrition and metabolism , 2012 | Pubmed ID: 23029606
Pneumococcal surface protein A inhibits complement deposition on the pneumococcal surface by competing with the binding of C-reactive protein to cell-surface phosphocholine.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2012 | Pubmed ID: 23105137
C-reactive protein exacerbates renal ischemia-reperfusion injury.
American journal of physiology. Renal physiology Jun, 2013 | Pubmed ID: 23535585
A Selective Inhibitor of Human C-reactive Protein Translation Is Efficacious In Vitro and in C-reactive Protein Transgenic Mice and Humans.
Molecular therapy. Nucleic acids , 2012 | Pubmed ID: 23629027
Multiple lupus-associated ITGAM variants alter Mac-1 functions on neutrophils.
Arthritis and rheumatism Nov, 2013 | Pubmed ID: 23918739
C-reactive protein promotes acute kidney injury by impairing G1/S-dependent tubular epithelium cell regeneration.
Clinical science (London, England : 1979) May, 2014 | Pubmed ID: 24206243
Inhibiting C-reactive protein for the treatment of cardiovascular disease: promising evidence from rodent models.
Mediators of inflammation , 2014 | Pubmed ID: 24803739
Associations between Abnormal Rod-Mediated Dark Adaptation and Health and Functioning in Older Adults with Normal Macular Health.
Investigative ophthalmology & visual science May, 2014 | Pubmed ID: 24854857
Estrogen effects on vascular inflammation are age dependent: role of estrogen receptors.
Arteriosclerosis, thrombosis, and vascular biology Jul, 2014 | Pubmed ID: 24876352
1Genetics and Genomic Sciences Graduate Program, University of Alabama at Birmingham,
2, Birmingham Veterans Affairs Medical Center,
3Department of Pathology, University of Alabama at Birmingham,
4Department of Biomedical Engineering, University of Alabama at Birmingham,
5Department of Medicine, University of Alabama at Birmingham
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved